Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to asse...Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to assess this complex toxicity endpoint and will be valuable for screening emerging pollutants as well as for m anaging new chemicals in China.Currently,there are few published DART prediction models in China,but many related research and development projects are in progress.In 2013,WU et al.published an expert rule-based DART decision tree(DT).This DT relies on known chemical structures linked to DART to forecast DART potential of a given chemical.Within this procedure,an accurate DART data interpretation is the foundation of building and expanding the DT.This paper excerpted case studies demonstrating DART data curation and interpretation of four chemicals(including 8-hydroxyquinoline,3,5,6-trichloro-2-pyridinol,thiacloprid,and imidacloprid)to expand the existing DART DT.Chemicals were first selected from the database of Solid Waste and Chemicals Management Center,Ministry of Ecology and Environment(MEESCC)in China.The structures of these 4 chemicals were analyzed and preliminarily grouped by chemists based on core structural features,functional groups,receptor binding property,metabolism,and possible mode of actions.Then,the DART conclusion was derived by collecting chemical information,searching,integrating,and interpreting DART data by the toxicologists.Finally,these chemicals were classified into either an existing category or a new category via integrating their chemical features,DART conclusions,and biological properties.The results showed that 8-hydroxyquinoline impacted estrous cyclicity,s exual organ weights,and embryonal development,and 3,5,6-trichloro-2-pyridinol caused central nervous system(CNS)malformations,which were added to an existing subcategory 8e(aromatic compounds with multi-halogen and nitro groups)of the DT.Thiacloprid caused dystocia and fetal skeletal malformation,and imidacloprid disrupted the endocrine system and male fertility.They both contain 2-chloro-5-methylpyridine substituted imidazolidine c yclic ring,which were expected to create a new category of neonicotinoids.The current work delineates a t ransparent process of curating toxicological data for the purpose of DART data interpretation.In the presence of sufficient related structures and DART data,the DT can be expanded by iteratively adding chemicals within the a pplicable domain of each category or subcategory.This DT can potentially serve as a tool for screening emerging pollutants and assessing new chemicals in China.展开更多
With the aim of reducing the cost of developing internal combustion engines,while at the same time investigating different geometries,layouts and fuels,3D-CFD-CHT simulations represent an indispensable part for the de...With the aim of reducing the cost of developing internal combustion engines,while at the same time investigating different geometries,layouts and fuels,3D-CFD-CHT simulations represent an indispensable part for the development of new technologies.These tools are increasingly used by manufacturers,as a screening process before building the first prototype.This paper presents an innovative methodology for virtual engine development.The 3D-CFD tool QuickSim,developed at FKFS,allows both a significant reduction in computation time and an extension of the simulated domain for complete engine systems.This is possible thanks to a combination of coarse meshes and self-developed internal combustion engine models,which simultaneously ensure high predictability.The present work demonstrates the capabilities of this innovative methodology for the design and optimization of different engines and fuels with the goal of achieving the highest possible combustion efficiencies and pollutant reductions.The analysis focuses on the influence of different fuels such as hydrogen,methanol,synthetic gasolines and methane on different engine geometries,in combination with suitable injection and ignition systems,including passive and active pre-chambers.Lean operations as well as knock reduction are discussed,particularly for methane and hydrogen injection.Finally,it is shown how depending on the chosen fuel,an appropriate ad-hoc engine layout can be designed to increase the indicated efficiency of the respective engines.展开更多
Background SRO(Similar to RCD1)genes family is largely recognized for their importance in the growth,develop-ment,and in responding to environmental stresses.However,genome-wide identification and functional character...Background SRO(Similar to RCD1)genes family is largely recognized for their importance in the growth,develop-ment,and in responding to environmental stresses.However,genome-wide identification and functional characteri-zation of SRO genes from cotton species have not been reported so far.Results A total of 36 SRO genes were identified from four cotton species.Phylogenetic analysis divided these genes into three groups with distinct structure.Syntenic and chromosomal distribution analysis indicated uneven distribu-tion of GaSRO,GrSRO,GhSRO,and GbSRO genes on A2,D5 genomes,Gh-At,Gh-Dt,Gb-At,and Gb-Dt subgenomes,respectively.Gene duplication analysis revealed the presence of six duplicated gene pairs among GhSRO genes.In promoter analysis,several elements responsive to the growth,development and hormones were found in GhSRO genes,implying gene induction during cotton growth and development.Several miRNAs responsive to plant growth and abiotic stress were predicted to target 12 GhSRO genes.Organ-specific expression profiling demonstrated the roles of GhSRO genes in one or more tissues.In addition,specific expression pattern of some GhSRO genes dur-ing ovule development depicted their involvement in these developmental processes.Conclusion The data presented in this report laid a foundation for understanding the classification and functions of SRO genes in cotton.展开更多
Background Aphis gossypii(Hemiptera:Aphididae)is a worldwide polyphagous phloem-feeding agricultural pest,and it can produce offspring by sexual or asexual reproduction.Compared with dozens of generations by parthenog...Background Aphis gossypii(Hemiptera:Aphididae)is a worldwide polyphagous phloem-feeding agricultural pest,and it can produce offspring by sexual or asexual reproduction.Compared with dozens of generations by parthenogenesis,sexual reproduction is performed in only one generation within one year,and little is known about the sexual reproduction of A.gossypii.In this study,sexual females of A.gossypii were successfully obtained through a previously established induction platform,and the morphological characteristics,developmental dynamics,and temporal gene expression were examined.Subsequently,signaling pathways potentially involved in regulating the growth,development,and reproduction of sexual females were investigated.Results The morphological observation showed that from the 1st instar nymph to adult,sexual females exhibited a gradually deepened body color,an enlarged body size,longer antennae with a blackened end,and obviously protruding cauda(in adulthood).The anatomy found that the ovaries of sexual females developed rapidly from the 2^(nd)instar nymph,and the embedded oocytes matured in adulthood.In addition,time-course transcriptome analysis revealed that gene expression profiles across the development of sexual females fell into 9 clusters with distinct patterns,in which gene expression levels in clusters 1,5,and 8 peaked at the 2^(nd)instar nymphal stage with the largest number of up-regulated genes,suggesting that the 2^(nd)instar nymph was an important ovary development period.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis revealed that a large number of genes in the sexual female adult were enriched in the TGF-beta signaling pathway and Forkhead box O(FoxO)signaling pathway,highlighting their important role in sexual female adult development and reproduction.Conclusion The morphological changes of the sexual female at each developmental stage were revealed for the first time.In addition,time-course transcriptomic analyses suggest genes enriched in the TGF-beta signaling pathway and FoxO signaling pathway probably contribute to regulating the development and oocyte maturation of sexual females.Overall,these findings will facilitate the regulating mechanism research in the growth and development of sexual females by providing candidate genes.展开更多
Solid oxide fuel cell(SOFC) technology and its status and problems were briefly described.Several topics for furtherresearch and development were proposed.
At the 19th G20 Summit in Brazil in November 2024,China promoted the development of sustainable solutions to climate change,biodiversity loss,and environmental pollution.This continued the theme of the 2016 G20 Hangzh...At the 19th G20 Summit in Brazil in November 2024,China promoted the development of sustainable solutions to climate change,biodiversity loss,and environmental pollution.This continued the theme of the 2016 G20 Hangzhou Summit,at which China placed development at the center of the G20’s macroeconomic policy coordination for the first time,adopting the G20 Action Plan on the United Nations 2030 Agenda for Sustainable Development and the G20 Initiative on Supporting Industrialization in Africa and Least Developed Countries.In Brazil,China announced actions on advancing modernization in Africa over the next three years with a Chinese commitment of RMB360 billion yuan in financial support.In this article,we examine the potential role of geoscience research and practice in development,particularly in the sustainable use of natural resources,the prevention of climate change impacts,as well as mitigation of geo-hazards and their health implications,indicating the areas where China’s geoscience for Africa is strong and where it requires more effort.We find that although China is the world’s leading publisher of scientific papers,its contribution to geoscience in Africa(the globe’s fastest-growing economic area),as shown by bibliometric research,appears to be rather small and inconsistent with the research priorities of Africa.Amongst the priorities for geoscience research in Africa,which are not addressed substantially by the research conducted so far,are sustainable mineral and hydrocarbon development,hydrology and hydrogeology,climate change and resilience,natural hazards,medical geology,agrominerals,and geoscience education and training.A particular opportunity for African nations is the presence of critical minerals-minerals needed for the energy transition and for batteries for electric cars in particular.Africa is well-endowed with many of these critical materials,such as rare earth elements and platinum group metals.Several research groups stress the need for the agency on the part of African institutions to map out these valuable resources,understand their value and the economics and sustainability of their extraction,encourage local business,attract investment,and scrutinize proposals from potential international investors to get the best deals.A strong point of existing China-led geoscience development includes the Deep-time Digital Earth(DDE)program online computing platform and its artificial intelligence tool GeoGPT,which is being developed in partnership with Zhejiang Laboratory.These are being developed with strong China funding support for free and wide global access,with a particular focus on Africa.These advanced tools will help to place the agency of development squarely in the hands of African scientists and institutions.In summary,the following are recommended:(1)a more coordinated and strategic approach to China-led geoscience research in Africa;(2)an Africa-centered,geoscience funding initiative that concentrates on relevant topics to the continent such as critical minerals exploration and other geological resources,materials and processes and their health implications on the populations and ecosystems in general,as well as climate change and climate change resilience;and(3)continued support for China-led international initiatives that seek to increase the agency and capacity of Africa geoscience researchers,for example the Deep-time Digital Earth platform.展开更多
Currently,research on N^(6)-methyladenine(m^(6)A)is extensive in the field of oncology,while studies involving m^(6)A and skin diseases remain relatively limited.Based on existing reports,we searched PubMed and Web of...Currently,research on N^(6)-methyladenine(m^(6)A)is extensive in the field of oncology,while studies involving m^(6)A and skin diseases remain relatively limited.Based on existing reports,we searched PubMed and Web of Science for literature related to m^(6)A and dermatological conditions.Analysis of citation counts and journal impact factors revealed a significant upward trend in the volume of m^(6)A-related research.Term frequency analysis of titles and abstracts indicated that studies mainly focus on skin tumors and inflammatory or immune-related skin diseases,particularly melanoma,psoriasis,and skin development.Transcriptomic data from the Gene Expression Omnibus(GEO)were analyzed,revealing differential expression of m^(6)A-related genes in 4 types of skin tumors(including squamous cell carcinoma and basal cell carcinoma)as well as in inflammatory skin diseases such as psoriasis and atopic dermatitis,and potential mechanisms of action were also explored.Findings suggest that m^(6)A modifications exhibit heterogeneity between neoplastic and nonneoplastic skin diseases.However,the regulatory mechanisms of m^(6)A dynamic modifications on key genes involved in dermatological disorders remain unclear and warrant further investigation.展开更多
In China,the primary energy bases and the energyrequirement areas are mismatched,which presents theremote and reverse distribution characteristics,and thelarge-scale power flow is from the west to the cast andfrom the...In China,the primary energy bases and the energyrequirement areas are mismatched,which presents theremote and reverse distribution characteristics,and thelarge-scale power flow is from the west to the cast andfrom the north to the south.In this paper,according tothe above characteristics and the power flow pattern,thelarge-scale,high-efficiency and long-distance UHVACand UHVDC combined transmission scheme is investi-gated and proposed,and the development mode ofChina's power grid and the planning scheme of‘NorthChina-Central China-East China'synchronous UHV gridwhich can satisfy the healthy and sustainabledevelopment of China's economy and society is proposedand optimized.展开更多
The current popular methods for decision making and project optimisation in mine ventilation contain a number of deficiencies as they are solely based on either subjective knowledge or objective information.This paper...The current popular methods for decision making and project optimisation in mine ventilation contain a number of deficiencies as they are solely based on either subjective knowledge or objective information.This paper presents a new approach to rank the alternatives by G1-coefficient of variation method.The focus of this approach is the use of the combination weighing,which is able to compensate for the deficiencies in the method of evaluation index single weighing.In the case study,an appropriate evaluation index system was established to determine the evaluation value of each ventilation mode.Then the proposed approach was used to select the best development face ventilation mode.The result shows that the proposed approach is able to rank the alternative development face ventilation mode reasonably,the combination weighing method had the advantages of both subjective and objective weighing methods in that it took into consideration of both the experience and wisdom of experts,and the new changes in objective conditions.This approach provides a more reasonable and reliable procedure to analyse and evaluate different ventilation modes.展开更多
The defence sector is now at an advanced level,catering to the global scenario,and countries also invest heavily in research and development.Countries around the world have spent a lot of money on research and develop...The defence sector is now at an advanced level,catering to the global scenario,and countries also invest heavily in research and development.Countries around the world have spent a lot of money on research and development over the years in order to stay ahead of their competitors.Lightweight materials are critical in defence applications because they allow components to be lighter without sacrificing strength.This review provides an overview of the research related to defence applications.The book provides comprehensive details on current trends in the application of lightweight materials in defence.This review also includes historical and current perspectives on defence technologies.It discusses uses of lightweight materials such as metal matrix composites,polymer composites,ceramic matrix composites,fiber composites in defence sectors Finally,the review paper also emphasizes future military applications of lightweight materials.展开更多
Rehabilitation(amendment and vegetation establishment)on bauxite residue is viewed as a promising strategy to stabilize the surface and initiate soil development.However,such approaches are inhibited by high pH,high e...Rehabilitation(amendment and vegetation establishment)on bauxite residue is viewed as a promising strategy to stabilize the surface and initiate soil development.However,such approaches are inhibited by high pH,high exchangeable sodium(ESP)and poor nutrient status.Amendment with gypsum is effective in improving residue physical and chemical properties and promoting seed establishment and growth.Application of organics(e.g.compost)can address nutrient deficiencies but supplemental fertilizer additions may be required.A series of germination bioassays were performed on residue to determine candidate species and optimum rehabilitation application rates.Subsequent field trials assessed establishment of grassland species Holcus lanatus and Trifolium pratense as well as physical and chemical properties of amended residue.Follow up monitoring over five years assessed elemental content in grassland and species dynamics.With co-application of the amendments several grassland species can grow on the residue.Over time other plant species can invade the restored area and fast growing nutrient demanding grasses are replaced.Scrub species can establish within a 5 Yr period and there is evidence of nutrient cycling.High pH,sodicity and nutrient deficiencies are the major limiting factors to establishing grassland on residue.Following restoration several plant species can grow on amended residue.展开更多
Resource allocation for an equipment development task is a complex process owing to the inherent characteristics,such as large amounts of input resources,numerous sub-tasks,complex network structures,and high degrees ...Resource allocation for an equipment development task is a complex process owing to the inherent characteristics,such as large amounts of input resources,numerous sub-tasks,complex network structures,and high degrees of uncertainty.This paper presents an investigation into the influence of resource allocation on the duration and cost of sub-tasks.Mathematical models are constructed for the relationships of the resource allocation quantity with the duration and cost of the sub-tasks.By considering the uncertainties,such as fluctuations in the sub-task duration and cost,rework iterations,and random overlaps,the tasks are simulated for various resource allocation schemes.The shortest duration and the minimum cost of the development task are first formulated as the objective function.Based on a multi-objective particle swarm optimization(MOPSO)algorithm,a multi-objective evolutionary algorithm is constructed to optimize the resource allocation scheme for the development task.Finally,an uninhabited aerial vehicle(UAV)is considered as an example of a development task to test the algorithm,and the optimization results of this method are compared with those based on non-dominated sorting genetic algorithm-II(NSGA-II),non-dominated sorting differential evolution(NSDE)and strength pareto evolutionary algorithm-II(SPEA-II).The proposed method is verified for its scientific approach and effectiveness.The case study shows that the optimization of the resource allocation can greatly aid in shortening the duration of the development task and reducing its cost effectively.展开更多
The process of urbanization affects the urban warming.The change of urban warming was investigated by several urbanization factors in Changsha,China.The data of surface temperature(minimum,maximum and mean) of Changsh...The process of urbanization affects the urban warming.The change of urban warming was investigated by several urbanization factors in Changsha,China.The data of surface temperature(minimum,maximum and mean) of Changsha were analyzed to understand the possible effects of urbanization on the climate of this region owing to the population growth,built-up area expansion and energy consumption increases.The weights of these three factors were calculated by the analytical hierarchy process(AHP).Then,three weights were simulated with nonlinear method to obtain the urbanization development rate which was utilized to reveal the influence of the urbanization factors on the surface temperature.The result shows that there is a significant upward trend in the urban temperatures of Changsha.The temperature increase seems to be closely related to the rate of urbanization between 1993 and 2008,and there is an evidential increase trend of the influence on urban temperature by urbanization during 16 years.It is a quantifiable approach measuring the relationship between urbanization and urban eco-environment,and can be applied for the urban sustainability.展开更多
Lithography is one of the most important and complicated key equipment for the integr ated circuit man ufacture.The 2一D positioning device is the importan t subsystem of lithography.Compared with conventional 2一D po...Lithography is one of the most important and complicated key equipment for the integr ated circuit man ufacture.The 2一D positioning device is the importan t subsystem of lithography.Compared with conventional 2一D positioning systems with cumbersome stacked arrangement,the 2-D positioning systems with planar motors have received increasing attention recently.Currently,many types of planar motors have been proposed.展开更多
Based on the characteristics of large flow rate , low head , short annual operation time , and high reliability of the city flood-control pumping stations , a new-type shaft tubular pumping system featuring a shaft su...Based on the characteristics of large flow rate , low head , short annual operation time , and high reliability of the city flood-control pumping stations , a new-type shaft tubular pumping system featuring a shaft suction box and a siphon-type discharge passage with a vacuum breaker as the cutoff device was developed , which possesses such advantages as simple structure , reliable cutoff , and high energy performance.Taking some pumping stations as the case studies , in the light of the specified operation conditions , the hydraulic optimal design of the shaft-type tubular pumping system was determined and the optimized shape of the system was recommended.The performance prediction based on the computational fluid dynamics methodology was determined and the model test verification was conducted.The results show that the predicted data agree with the experimental head and efficiency so that both methods can be used to determine the performance of a real pumping station.Finally , the in-situ measurements of a pumping station during the commissioning period further verified that the shaft-type tubular pumping station with a siphon discharge passage is of higher efficiency , more reliable and stable.展开更多
This article introduced the new methods on the research of the wild flowers and plants idioplasmic resources, elaborated the introduction and domestication and exploitation of wild flowers and plants idioplasmatic res...This article introduced the new methods on the research of the wild flowers and plants idioplasmic resources, elaborated the introduction and domestication and exploitation of wild flowers and plants idioplasmatic resources and the sustainable development of flowers and plants industry in China, and put forward some proposals on the existing question and the prospects for the development.展开更多
China is the largest producer and trader of aquatic products in the world, but does not mean that it belongs to the strongest power group of aquatic production and trade. This paper objectively analyzed the main probl...China is the largest producer and trader of aquatic products in the world, but does not mean that it belongs to the strongest power group of aquatic production and trade. This paper objectively analyzed the main problems existing in the highspeed development of China＇s aquatic product industry by empirical analysis. For example, the situation of quality and safety of aquatic products is serious now; the basic conditions of aquaculture lag behind the production development; aquatic industry is still in a low level of development and organization; and the quality and safety of aquatic products is the most main problem. This paper also revealed that fish would be the main source of animal-derived food, and the demand of characteristic aquatic products would continuously go up. Aquatic processing has initially formed a standard system. It drew a conclusion that it would be a good opportunity for China＇s aquatic processing industry in the future展开更多
DCPTA （2-diethylaminoethyl-3, 4-dichlorophenylether） is a new plant regulator which can be used to regulate growth and development for crops. Experiments on maize seedlings were conducted in the growth chamber to st...DCPTA （2-diethylaminoethyl-3, 4-dichlorophenylether） is a new plant regulator which can be used to regulate growth and development for crops. Experiments on maize seedlings were conducted in the growth chamber to study the effects of foliar applied DCPTA. The plant pots were placed in a completely randomized design with three replicates. The maize seedlings were treated with 0 mg·L-1 （control）, 20 mg·L-1 and 40 mg·L-1 DCPTA solution. The effects of DCPTA on the photosynthetic characteristics （photosynthesis, stomata conductance, intercellular CO2, and transpiration rate）, related physiological characteristics （contents of soluble sugar and starch）, chlorophyll fluorescence parameters （Fo, Fro, Fv/Fm, Fv/Fo, qP, and qN） and the weight of dry matter in maize seedling were studied. The results showed that DCPTA enhanced photosynthesis of maize seedling. In general, photosynthetic rate in leaves was significantly promoted through spraying DCPTA solution, and 40 rag＂ L~ DCPTA was found to be the best concentration for maize. The relationship between stomata conductance and transpiration rate in maize leaves could be described as linear. With regard to the chlorophyll fluorescence parameters, our fmdings showed that 40 mg·L-1 DCPTA in maize seedling caused an increase in Fm, Fv/Fm, Fm/Fo, qP and a decrease in Fo and qN at some time points checked. It is suggested that DCPTA increased photosynthetic rate by raising both the content of chlorophyll and activities of PSII and the contents of sugar and starch. Compared with the control, the treated maize seedling caused an increase in plant height, root length, shoot dry mass, root dry mass, or the total （root plus shoot） dry mass.展开更多
文摘Developmental and reproductive toxicity(DART)endpoint entails a toxicological assessment of all developmental stages and reproductive cycles of an organism.In silico tools to predict DART will provide a method to assess this complex toxicity endpoint and will be valuable for screening emerging pollutants as well as for m anaging new chemicals in China.Currently,there are few published DART prediction models in China,but many related research and development projects are in progress.In 2013,WU et al.published an expert rule-based DART decision tree(DT).This DT relies on known chemical structures linked to DART to forecast DART potential of a given chemical.Within this procedure,an accurate DART data interpretation is the foundation of building and expanding the DT.This paper excerpted case studies demonstrating DART data curation and interpretation of four chemicals(including 8-hydroxyquinoline,3,5,6-trichloro-2-pyridinol,thiacloprid,and imidacloprid)to expand the existing DART DT.Chemicals were first selected from the database of Solid Waste and Chemicals Management Center,Ministry of Ecology and Environment(MEESCC)in China.The structures of these 4 chemicals were analyzed and preliminarily grouped by chemists based on core structural features,functional groups,receptor binding property,metabolism,and possible mode of actions.Then,the DART conclusion was derived by collecting chemical information,searching,integrating,and interpreting DART data by the toxicologists.Finally,these chemicals were classified into either an existing category or a new category via integrating their chemical features,DART conclusions,and biological properties.The results showed that 8-hydroxyquinoline impacted estrous cyclicity,s exual organ weights,and embryonal development,and 3,5,6-trichloro-2-pyridinol caused central nervous system(CNS)malformations,which were added to an existing subcategory 8e(aromatic compounds with multi-halogen and nitro groups)of the DT.Thiacloprid caused dystocia and fetal skeletal malformation,and imidacloprid disrupted the endocrine system and male fertility.They both contain 2-chloro-5-methylpyridine substituted imidazolidine c yclic ring,which were expected to create a new category of neonicotinoids.The current work delineates a t ransparent process of curating toxicological data for the purpose of DART data interpretation.In the presence of sufficient related structures and DART data,the DT can be expanded by iteratively adding chemicals within the a pplicable domain of each category or subcategory.This DT can potentially serve as a tool for screening emerging pollutants and assessing new chemicals in China.
文摘With the aim of reducing the cost of developing internal combustion engines,while at the same time investigating different geometries,layouts and fuels,3D-CFD-CHT simulations represent an indispensable part for the development of new technologies.These tools are increasingly used by manufacturers,as a screening process before building the first prototype.This paper presents an innovative methodology for virtual engine development.The 3D-CFD tool QuickSim,developed at FKFS,allows both a significant reduction in computation time and an extension of the simulated domain for complete engine systems.This is possible thanks to a combination of coarse meshes and self-developed internal combustion engine models,which simultaneously ensure high predictability.The present work demonstrates the capabilities of this innovative methodology for the design and optimization of different engines and fuels with the goal of achieving the highest possible combustion efficiencies and pollutant reductions.The analysis focuses on the influence of different fuels such as hydrogen,methanol,synthetic gasolines and methane on different engine geometries,in combination with suitable injection and ignition systems,including passive and active pre-chambers.Lean operations as well as knock reduction are discussed,particularly for methane and hydrogen injection.Finally,it is shown how depending on the chosen fuel,an appropriate ad-hoc engine layout can be designed to increase the indicated efficiency of the respective engines.
文摘Background SRO(Similar to RCD1)genes family is largely recognized for their importance in the growth,develop-ment,and in responding to environmental stresses.However,genome-wide identification and functional characteri-zation of SRO genes from cotton species have not been reported so far.Results A total of 36 SRO genes were identified from four cotton species.Phylogenetic analysis divided these genes into three groups with distinct structure.Syntenic and chromosomal distribution analysis indicated uneven distribu-tion of GaSRO,GrSRO,GhSRO,and GbSRO genes on A2,D5 genomes,Gh-At,Gh-Dt,Gb-At,and Gb-Dt subgenomes,respectively.Gene duplication analysis revealed the presence of six duplicated gene pairs among GhSRO genes.In promoter analysis,several elements responsive to the growth,development and hormones were found in GhSRO genes,implying gene induction during cotton growth and development.Several miRNAs responsive to plant growth and abiotic stress were predicted to target 12 GhSRO genes.Organ-specific expression profiling demonstrated the roles of GhSRO genes in one or more tissues.In addition,specific expression pattern of some GhSRO genes dur-ing ovule development depicted their involvement in these developmental processes.Conclusion The data presented in this report laid a foundation for understanding the classification and functions of SRO genes in cotton.
基金funded by National Natural Science Foundation of China(No.32102214)Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences+1 种基金China Agriculture Research System(CARS-15-21)National Key R&D Program of China(2022YFD1400300)。
文摘Background Aphis gossypii(Hemiptera:Aphididae)is a worldwide polyphagous phloem-feeding agricultural pest,and it can produce offspring by sexual or asexual reproduction.Compared with dozens of generations by parthenogenesis,sexual reproduction is performed in only one generation within one year,and little is known about the sexual reproduction of A.gossypii.In this study,sexual females of A.gossypii were successfully obtained through a previously established induction platform,and the morphological characteristics,developmental dynamics,and temporal gene expression were examined.Subsequently,signaling pathways potentially involved in regulating the growth,development,and reproduction of sexual females were investigated.Results The morphological observation showed that from the 1st instar nymph to adult,sexual females exhibited a gradually deepened body color,an enlarged body size,longer antennae with a blackened end,and obviously protruding cauda(in adulthood).The anatomy found that the ovaries of sexual females developed rapidly from the 2^(nd)instar nymph,and the embedded oocytes matured in adulthood.In addition,time-course transcriptome analysis revealed that gene expression profiles across the development of sexual females fell into 9 clusters with distinct patterns,in which gene expression levels in clusters 1,5,and 8 peaked at the 2^(nd)instar nymphal stage with the largest number of up-regulated genes,suggesting that the 2^(nd)instar nymph was an important ovary development period.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis revealed that a large number of genes in the sexual female adult were enriched in the TGF-beta signaling pathway and Forkhead box O(FoxO)signaling pathway,highlighting their important role in sexual female adult development and reproduction.Conclusion The morphological changes of the sexual female at each developmental stage were revealed for the first time.In addition,time-course transcriptomic analyses suggest genes enriched in the TGF-beta signaling pathway and FoxO signaling pathway probably contribute to regulating the development and oocyte maturation of sexual females.Overall,these findings will facilitate the regulating mechanism research in the growth and development of sexual females by providing candidate genes.
文摘Solid oxide fuel cell(SOFC) technology and its status and problems were briefly described.Several topics for furtherresearch and development were proposed.
文摘At the 19th G20 Summit in Brazil in November 2024,China promoted the development of sustainable solutions to climate change,biodiversity loss,and environmental pollution.This continued the theme of the 2016 G20 Hangzhou Summit,at which China placed development at the center of the G20’s macroeconomic policy coordination for the first time,adopting the G20 Action Plan on the United Nations 2030 Agenda for Sustainable Development and the G20 Initiative on Supporting Industrialization in Africa and Least Developed Countries.In Brazil,China announced actions on advancing modernization in Africa over the next three years with a Chinese commitment of RMB360 billion yuan in financial support.In this article,we examine the potential role of geoscience research and practice in development,particularly in the sustainable use of natural resources,the prevention of climate change impacts,as well as mitigation of geo-hazards and their health implications,indicating the areas where China’s geoscience for Africa is strong and where it requires more effort.We find that although China is the world’s leading publisher of scientific papers,its contribution to geoscience in Africa(the globe’s fastest-growing economic area),as shown by bibliometric research,appears to be rather small and inconsistent with the research priorities of Africa.Amongst the priorities for geoscience research in Africa,which are not addressed substantially by the research conducted so far,are sustainable mineral and hydrocarbon development,hydrology and hydrogeology,climate change and resilience,natural hazards,medical geology,agrominerals,and geoscience education and training.A particular opportunity for African nations is the presence of critical minerals-minerals needed for the energy transition and for batteries for electric cars in particular.Africa is well-endowed with many of these critical materials,such as rare earth elements and platinum group metals.Several research groups stress the need for the agency on the part of African institutions to map out these valuable resources,understand their value and the economics and sustainability of their extraction,encourage local business,attract investment,and scrutinize proposals from potential international investors to get the best deals.A strong point of existing China-led geoscience development includes the Deep-time Digital Earth(DDE)program online computing platform and its artificial intelligence tool GeoGPT,which is being developed in partnership with Zhejiang Laboratory.These are being developed with strong China funding support for free and wide global access,with a particular focus on Africa.These advanced tools will help to place the agency of development squarely in the hands of African scientists and institutions.In summary,the following are recommended:(1)a more coordinated and strategic approach to China-led geoscience research in Africa;(2)an Africa-centered,geoscience funding initiative that concentrates on relevant topics to the continent such as critical minerals exploration and other geological resources,materials and processes and their health implications on the populations and ecosystems in general,as well as climate change and climate change resilience;and(3)continued support for China-led international initiatives that seek to increase the agency and capacity of Africa geoscience researchers,for example the Deep-time Digital Earth platform.
基金supported by the National Natural Science Foundation,China(82103704).
文摘Currently,research on N^(6)-methyladenine(m^(6)A)is extensive in the field of oncology,while studies involving m^(6)A and skin diseases remain relatively limited.Based on existing reports,we searched PubMed and Web of Science for literature related to m^(6)A and dermatological conditions.Analysis of citation counts and journal impact factors revealed a significant upward trend in the volume of m^(6)A-related research.Term frequency analysis of titles and abstracts indicated that studies mainly focus on skin tumors and inflammatory or immune-related skin diseases,particularly melanoma,psoriasis,and skin development.Transcriptomic data from the Gene Expression Omnibus(GEO)were analyzed,revealing differential expression of m^(6)A-related genes in 4 types of skin tumors(including squamous cell carcinoma and basal cell carcinoma)as well as in inflammatory skin diseases such as psoriasis and atopic dermatitis,and potential mechanisms of action were also explored.Findings suggest that m^(6)A modifications exhibit heterogeneity between neoplastic and nonneoplastic skin diseases.However,the regulatory mechanisms of m^(6)A dynamic modifications on key genes involved in dermatological disorders remain unclear and warrant further investigation.
文摘In China,the primary energy bases and the energyrequirement areas are mismatched,which presents theremote and reverse distribution characteristics,and thelarge-scale power flow is from the west to the cast andfrom the north to the south.In this paper,according tothe above characteristics and the power flow pattern,thelarge-scale,high-efficiency and long-distance UHVACand UHVDC combined transmission scheme is investi-gated and proposed,and the development mode ofChina's power grid and the planning scheme of‘NorthChina-Central China-East China'synchronous UHV gridwhich can satisfy the healthy and sustainabledevelopment of China's economy and society is proposedand optimized.
基金Projects(51504286,51374242)supported by the National Natural Science Foundation of ChinaProject(2015M572270)supported by China Postdoctoral Science FoundationProject(2015RS4004)supported by the Science and Technology Plan of Hunan Province,China
文摘The current popular methods for decision making and project optimisation in mine ventilation contain a number of deficiencies as they are solely based on either subjective knowledge or objective information.This paper presents a new approach to rank the alternatives by G1-coefficient of variation method.The focus of this approach is the use of the combination weighing,which is able to compensate for the deficiencies in the method of evaluation index single weighing.In the case study,an appropriate evaluation index system was established to determine the evaluation value of each ventilation mode.Then the proposed approach was used to select the best development face ventilation mode.The result shows that the proposed approach is able to rank the alternative development face ventilation mode reasonably,the combination weighing method had the advantages of both subjective and objective weighing methods in that it took into consideration of both the experience and wisdom of experts,and the new changes in objective conditions.This approach provides a more reasonable and reliable procedure to analyse and evaluate different ventilation modes.
文摘The defence sector is now at an advanced level,catering to the global scenario,and countries also invest heavily in research and development.Countries around the world have spent a lot of money on research and development over the years in order to stay ahead of their competitors.Lightweight materials are critical in defence applications because they allow components to be lighter without sacrificing strength.This review provides an overview of the research related to defence applications.The book provides comprehensive details on current trends in the application of lightweight materials in defence.This review also includes historical and current perspectives on defence technologies.It discusses uses of lightweight materials such as metal matrix composites,polymer composites,ceramic matrix composites,fiber composites in defence sectors Finally,the review paper also emphasizes future military applications of lightweight materials.
基金Projects(41877551,41842020)supported by the National Natural Science Foundation of ChinaProject supported by the Science Foundation Ireland 17/CDA/4778
文摘Rehabilitation(amendment and vegetation establishment)on bauxite residue is viewed as a promising strategy to stabilize the surface and initiate soil development.However,such approaches are inhibited by high pH,high exchangeable sodium(ESP)and poor nutrient status.Amendment with gypsum is effective in improving residue physical and chemical properties and promoting seed establishment and growth.Application of organics(e.g.compost)can address nutrient deficiencies but supplemental fertilizer additions may be required.A series of germination bioassays were performed on residue to determine candidate species and optimum rehabilitation application rates.Subsequent field trials assessed establishment of grassland species Holcus lanatus and Trifolium pratense as well as physical and chemical properties of amended residue.Follow up monitoring over five years assessed elemental content in grassland and species dynamics.With co-application of the amendments several grassland species can grow on the residue.Over time other plant species can invade the restored area and fast growing nutrient demanding grasses are replaced.Scrub species can establish within a 5 Yr period and there is evidence of nutrient cycling.High pH,sodicity and nutrient deficiencies are the major limiting factors to establishing grassland on residue.Following restoration several plant species can grow on amended residue.
基金supported by the National Natural Science Foundation of China(71690233)
文摘Resource allocation for an equipment development task is a complex process owing to the inherent characteristics,such as large amounts of input resources,numerous sub-tasks,complex network structures,and high degrees of uncertainty.This paper presents an investigation into the influence of resource allocation on the duration and cost of sub-tasks.Mathematical models are constructed for the relationships of the resource allocation quantity with the duration and cost of the sub-tasks.By considering the uncertainties,such as fluctuations in the sub-task duration and cost,rework iterations,and random overlaps,the tasks are simulated for various resource allocation schemes.The shortest duration and the minimum cost of the development task are first formulated as the objective function.Based on a multi-objective particle swarm optimization(MOPSO)algorithm,a multi-objective evolutionary algorithm is constructed to optimize the resource allocation scheme for the development task.Finally,an uninhabited aerial vehicle(UAV)is considered as an example of a development task to test the algorithm,and the optimization results of this method are compared with those based on non-dominated sorting genetic algorithm-II(NSGA-II),non-dominated sorting differential evolution(NSDE)and strength pareto evolutionary algorithm-II(SPEA-II).The proposed method is verified for its scientific approach and effectiveness.The case study shows that the optimization of the resource allocation can greatly aid in shortening the duration of the development task and reducing its cost effectively.
基金Projects(2008JT1013,2007JT3018,05SK3002) supported by the Key Program for Science and Technology in Hunan Province,ChinaProject(2007ZK2025) supported by the Key Program for Soft Science in Hunan Province,China
文摘The process of urbanization affects the urban warming.The change of urban warming was investigated by several urbanization factors in Changsha,China.The data of surface temperature(minimum,maximum and mean) of Changsha were analyzed to understand the possible effects of urbanization on the climate of this region owing to the population growth,built-up area expansion and energy consumption increases.The weights of these three factors were calculated by the analytical hierarchy process(AHP).Then,three weights were simulated with nonlinear method to obtain the urbanization development rate which was utilized to reveal the influence of the urbanization factors on the surface temperature.The result shows that there is a significant upward trend in the urban temperatures of Changsha.The temperature increase seems to be closely related to the rate of urbanization between 1993 and 2008,and there is an evidential increase trend of the influence on urban temperature by urbanization during 16 years.It is a quantifiable approach measuring the relationship between urbanization and urban eco-environment,and can be applied for the urban sustainability.
文摘Lithography is one of the most important and complicated key equipment for the integr ated circuit man ufacture.The 2一D positioning device is the importan t subsystem of lithography.Compared with conventional 2一D positioning systems with cumbersome stacked arrangement,the 2-D positioning systems with planar motors have received increasing attention recently.Currently,many types of planar motors have been proposed.
基金support by the 11th Five Year Key Project of China’s National Scientific Supporting Plan(Grant No.2006BAB04A03)the Hydraulic Engineering Project from the Water Resources Department of Jiangsu Province(Grant No.2010023)
文摘Based on the characteristics of large flow rate , low head , short annual operation time , and high reliability of the city flood-control pumping stations , a new-type shaft tubular pumping system featuring a shaft suction box and a siphon-type discharge passage with a vacuum breaker as the cutoff device was developed , which possesses such advantages as simple structure , reliable cutoff , and high energy performance.Taking some pumping stations as the case studies , in the light of the specified operation conditions , the hydraulic optimal design of the shaft-type tubular pumping system was determined and the optimized shape of the system was recommended.The performance prediction based on the computational fluid dynamics methodology was determined and the model test verification was conducted.The results show that the predicted data agree with the experimental head and efficiency so that both methods can be used to determine the performance of a real pumping station.Finally , the in-situ measurements of a pumping station during the commissioning period further verified that the shaft-type tubular pumping station with a siphon discharge passage is of higher efficiency , more reliable and stable.
文摘This article introduced the new methods on the research of the wild flowers and plants idioplasmic resources, elaborated the introduction and domestication and exploitation of wild flowers and plants idioplasmatic resources and the sustainable development of flowers and plants industry in China, and put forward some proposals on the existing question and the prospects for the development.
基金Supported by Ministry of Education in China (10YJC790240)
文摘China is the largest producer and trader of aquatic products in the world, but does not mean that it belongs to the strongest power group of aquatic production and trade. This paper objectively analyzed the main problems existing in the highspeed development of China＇s aquatic product industry by empirical analysis. For example, the situation of quality and safety of aquatic products is serious now; the basic conditions of aquaculture lag behind the production development; aquatic industry is still in a low level of development and organization; and the quality and safety of aquatic products is the most main problem. This paper also revealed that fish would be the main source of animal-derived food, and the demand of characteristic aquatic products would continuously go up. Aquatic processing has initially formed a standard system. It drew a conclusion that it would be a good opportunity for China＇s aquatic processing industry in the future
基金Supported by the National Natural Science Foundation of China(31201164)the Program of Science and Technology of Education Department of Heilongjiang Province(12521036)+2 种基金China Postdoctoral Science Foundation(2012M511434)Heilongjiang Province Postdoctoral Science Foundation(LBH-Z12036)the Doctoral Starting Up Foundation of Northeast Agricultural University(2012RCB01)
文摘DCPTA （2-diethylaminoethyl-3, 4-dichlorophenylether） is a new plant regulator which can be used to regulate growth and development for crops. Experiments on maize seedlings were conducted in the growth chamber to study the effects of foliar applied DCPTA. The plant pots were placed in a completely randomized design with three replicates. The maize seedlings were treated with 0 mg·L-1 （control）, 20 mg·L-1 and 40 mg·L-1 DCPTA solution. The effects of DCPTA on the photosynthetic characteristics （photosynthesis, stomata conductance, intercellular CO2, and transpiration rate）, related physiological characteristics （contents of soluble sugar and starch）, chlorophyll fluorescence parameters （Fo, Fro, Fv/Fm, Fv/Fo, qP, and qN） and the weight of dry matter in maize seedling were studied. The results showed that DCPTA enhanced photosynthesis of maize seedling. In general, photosynthetic rate in leaves was significantly promoted through spraying DCPTA solution, and 40 rag＂ L~ DCPTA was found to be the best concentration for maize. The relationship between stomata conductance and transpiration rate in maize leaves could be described as linear. With regard to the chlorophyll fluorescence parameters, our fmdings showed that 40 mg·L-1 DCPTA in maize seedling caused an increase in Fm, Fv/Fm, Fm/Fo, qP and a decrease in Fo and qN at some time points checked. It is suggested that DCPTA increased photosynthetic rate by raising both the content of chlorophyll and activities of PSII and the contents of sugar and starch. Compared with the control, the treated maize seedling caused an increase in plant height, root length, shoot dry mass, root dry mass, or the total （root plus shoot） dry mass.
