In this work,we employ the cache-enabled UAV to provide context information delivery to end devices that make timely and intelligent decisions.Different from the traditional network traffic,context information varies ...In this work,we employ the cache-enabled UAV to provide context information delivery to end devices that make timely and intelligent decisions.Different from the traditional network traffic,context information varies with time and brings in the ageconstrained requirement.The cached content items should be refreshed timely based on the age status to guarantee the freshness of user-received contents,which however consumes additional transmission resources.The traditional cache methods separate the caching and the transmitting,which are not suitable for the dynamic context information.We jointly design the cache replacing and content delivery based on both the user requests and the content dynamics to maximize the offloaded traffic from the ground network.The problem is formulated based on the Markov Decision Process(MDP).A sufficient condition of cache replacing is found in closed form,whereby a dynamic cache replacing and content delivery scheme is proposed based on the Deep Q-Network(DQN).Extensive simulations have been conducted.Compared with the conventional popularity-based and the modified Least Frequently Used(i.e.,LFU-dynamic)schemes,the UAV can offload around 30%traffic from the ground network by utilizing the proposed scheme in the urban scenario,according to the simulation results.展开更多
With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an...With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an important measurement in new trade protectionism. This article analyzes the replacement of TBT on tariff barrier for exporting countries, as well as the trading pattern of TBT in its maturing period through the discussion of macro strategies of surpassing TBT; meanwhile it also probes into the examination and supervision policies of governmental functional departments.展开更多
In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“...In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“TotalEnergies”inserted),this section should say:The authors would like to thank Moura Batteries for the financial support.展开更多
Since hydrate resources play a part of the stratigraphic framework structure in sediments,establishing a safe and economic method for hydrates exploitation remains the primary challenge to this day.Among the proposed ...Since hydrate resources play a part of the stratigraphic framework structure in sediments,establishing a safe and economic method for hydrates exploitation remains the primary challenge to this day.Among the proposed methods,the spontaneous displacement of CH_(4) from hydrate cages by CO_(2) seems to be a perfect mechanism to address gas production and CO_(2) storage,especially in today's strong demand for carbon reduction and replacing clean energy.After extensive lab researches,in the past decade,injecting a mixture of CO_(2) and small molecule gas has become a key means to enhance displacement efficiency and has great potential for application.However,there is a lack of in-depth research on gas flow in the reservoir,while the injected gas always passes through low-saturated hydrate areas with high permeability and then occurs gas channel in a short term,finally resulting in the decreases in gas production efficiency and produced gas quality.Therefore,we explored a new injection-production mode of alternate injection of N2 and CO_(2) in order to fully coordinate the advantages of N_(2) in enhanced hydrate decomposition and CO_(2) in solid storage and heat compensation.These alternate"taking"and"storing"processes perfectly repair the problem of the gas channel,achieving self-regulation effect of CH_(4) recovery and CO_(2) storage.The 3-D experimental results show that compared to the mixed gas injection,CH_(4) recovery is increased by>50%and CO_(2) storage is increased by>70%.Additionally,this alternate injection mode presented a better performance in CH_(4) concentration of produced gas and showed outstanding N_(2) utilization efficiency.Further,we analyzed its self-adaptive gas flow mechanism and proposed an application model of"one injection and multiple production".We look forward to this study accelerating the application of CO_(2)-CH_(4) replacement technology.展开更多
A notable portion of cachelines in real-world workloads exhibits inner non-uniform access behaviors.However,modern cache management rarely considers this fine-grained feature,which impacts the effective cache capacity...A notable portion of cachelines in real-world workloads exhibits inner non-uniform access behaviors.However,modern cache management rarely considers this fine-grained feature,which impacts the effective cache capacity of contemporary high-performance spacecraft processors.To harness these non-uniform access behaviors,an efficient cache replacement framework featuring an auxiliary cache specifically designed to retain evicted hot data was proposed.This framework reconstructs the cache replacement policy,facilitating data migration between the main cache and the auxiliary cache.Unlike traditional cacheline-granularity policies,the approach excels at identifying and evicting infrequently used data,thereby optimizing cache utilization.The evaluation shows impressive performance improvement,especially on workloads with irregular access patterns.Benefiting from fine granularity,the proposal achieves superior storage efficiency compared with commonly used cache management schemes,providing a potential optimization opportunity for modern resource-constrained processors,such as spacecraft processors.Furthermore,the framework complements existing modern cache replacement policies and can be seamlessly integrated with minimal modifications,enhancing their overall efficacy.展开更多
To the editor:Psychiatric theory,policy and practice are currently grappling with the risks and opportunities presented by artificial intelligence(AI)applications in mental healthcare.Synthesising data to generate dia...To the editor:Psychiatric theory,policy and practice are currently grappling with the risks and opportunities presented by artificial intelligence(AI)applications in mental healthcare.Synthesising data to generate diagnosis is an aspect of mental healthcare where AI is anticipated to have the greatest and soonest impact.1-4 While such technologies remain some distance from clinical application,preliminary evidence suggests AI-derived classifications may predict certain treatment outcomes and clinical trajectories,and could soon become available to supplement or replace traditional manual-based diagnostic assessment.展开更多
Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to...Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to medical complexity,ethical conflicts,and decision dilemmas in intensive care unit(ICU)settings.This study aimed to develop a decision aid(DA)for the family surrogate of critically ill patients to support their engagement in shared decision-making process with clinicians.Methods Development of DA employed a systematic process with user-centered design(UCD)principle,which included:(i)competitive analysis:searched,screened,and assessed the existing DAs to gather insights for design strategies,developmental techniques,and functionalities;(ii)user needs assessment:interviewed family surrogates in our hospital to explore target user group's decision-making experience and identify their unmet needs;(iii)evidence syntheses:integrate latest clinical evidence and pertinent information to inform the content development of DA.Results The competitive analysis included 16 relevant DAs,from which we derived valuable insights using existing resources.User decision needs were explored among a cohort of 15 family surrogates,revealing four thematic issues in decision-making,including stuck into dilemmas,sense of uncertainty,limited capacity,and delayed decision confirmation.A total of 27 articles were included for evidence syntheses.Relevant decision making knowledge on disease and treatment,as delineated in the literature sourced from decision support system or clinical guidelines,were formatted as the foundational knowledge base.Twenty-one items of evidence were extracted and integrated into the content panels of benefits and risks of RRT,possible outcomes,and reasons to choose.The DA was drafted into a web-based phototype using the elements of UCD.This platform could guide users in their preparation of decision-making through a sequential four-step process:identifying treatment options,weighing the benefits and risks,clarifying personal preferences and values,and formulating a schedule for formal shared decision-making with clinicians.Conclusions We developed a rapid prototype of DA tailored for family surrogate decision makers of critically ill patients in need of RRT in ICU setting.Future studies are needed to evaluate its usability,feasibility,and clinical effects of this intervention.展开更多
Background Epicardial adipose tissue(EAT)radiomics derived from cardiac computed tomography(CT)images may pr-ovide insights into EAT characteristics,which can further predict regression of left ventricular mass index(...Background Epicardial adipose tissue(EAT)radiomics derived from cardiac computed tomography(CT)images may pr-ovide insights into EAT characteristics,which can further predict regression of left ventricular mass index(LVMI)after transcath-eter aortic valve replacement(TAVR).This study aimed to develop and validate a radiomics nomogram based on pre-procedural EAT CT to predict inadequate LVMI regression following TAVR.Methods Inadequate LVMI regression was defined asΔLVMI%<15%at one-year post TAVR.Radiomics features from pre-procedural CT images were selected mainly by least absolute shrinkage and selection operator algorithm.The patients were ran-domly divided into the training and validation cohorts to establish and evaluate three feature classifier models based on the selec-ted features,using which the Radiomics scores(Radscores)were then calculated.A radiomics nomogram was constructed using independent risk factors and further assessed using area under the curve,calibration curve,and decision curve analysis.Results A total of 144 consecutive TAVR patients(42 patients with inadequate and 102 patients with adequate LVMI regres-sion)were randomly assigned to the training and validation cohorts(116 patients and 28 patients,respectively).A total of 1130 radiomics features from each patient yielded 6 features for the Radscore construction after selection,with logistic regression and support vector machine models favored.Subsequently,a nomogram based solely on the Radscore was constructed,with an area under the curve of 0.743 in the validation cohort,along with favorable decision curve analysis and calibration curves.Conclusions The developed radiomics nomogram,serving as a non-invasive tool,achieved satisfactory preoperative predic-tion of inadequate LVMI regression in TAVR patients,thereby facilitating clinical management.展开更多
多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)是重症监护病房(ICU)内患者最常见的死亡原因,而脓毒症或脓毒性休克是引起多器官功能衰竭的主要原因。过去几十年内体外血液净化技术取得了显著的进展,使得ICU内重症患...多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)是重症监护病房(ICU)内患者最常见的死亡原因,而脓毒症或脓毒性休克是引起多器官功能衰竭的主要原因。过去几十年内体外血液净化技术取得了显著的进展,使得ICU内重症患者的治疗有了许多新的仪器和技术方法。其中持续性肾脏替代治疗(continuous renal replacement therapy,CRRT)由于其对血流动力学更好的耐受性,展开更多
项目时间Project Period:2003-Now项目采用了置换与填充的规划思路,逐步添加改造,或延伸、或包裹、或渗入现有肌理,创造了一层新的相贯通的公共空间和设施。都市实践总体控制与使用者个性发挥的互动十分符合创意产业和厂房改造的特点。T...项目时间Project Period:2003-Now项目采用了置换与填充的规划思路,逐步添加改造,或延伸、或包裹、或渗入现有肌理,创造了一层新的相贯通的公共空间和设施。都市实践总体控制与使用者个性发挥的互动十分符合创意产业和厂房改造的特点。The main strategies of this project are replacing展开更多
With the prevalence of MOOCs,a heated discussion is raised about whether it can replace the traditional courses.This paper addresses the advantages of MOOCs and disadvantages of it in the English courses and answers t...With the prevalence of MOOCs,a heated discussion is raised about whether it can replace the traditional courses.This paper addresses the advantages of MOOCs and disadvantages of it in the English courses and answers the heated issue.展开更多
Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation ...Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT.Regional citrate anticoagulation(RCA)has been shown to potentially be safer and more effective,and is now recommended as the preferred anticoagulant method for CRRT.However,there is still a lack of unified standards for RCA management in the world,and there are many problems in using this method in clinical practice.The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association(CMDA)organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues,including the advantages and disadvantages of RCA in CRRT anticoagulation,the principle of RCA,parameter settings for RCA,monitoring of RCA(mainly metabolic acid-base disorders),and special issues during RCA.Based on the latest available research evidence as well as the paneled experts'clinical experience,considering the generalizability,suitability,and potential resource utilization,while also balancing clinical advantages and disadvantages,a total of 16 guideline recommendations were formed from the experts'consensus.展开更多
Galvanic deposition method was used to prepare the Pd/Ni-Al2O3-GD catalyst for the combustion of methane under lean conditions. The new catalyst and compared catalysts （Pd/Al2O3-IW, Pd-Ni/Al2O3-IW, Pd/Ni-Al2O3-IW） p...Galvanic deposition method was used to prepare the Pd/Ni-Al2O3-GD catalyst for the combustion of methane under lean conditions. The new catalyst and compared catalysts （Pd/Al2O3-IW, Pd-Ni/Al2O3-IW, Pd/Ni-Al2O3-IW） prepared by incipient wetness impregnation were characterized by N2-physisorption, XRD and TEM to clarify particle size and size distribution of palladium species. Combined O2-TPD and XPS results with the catalytic data, it shows that the surface palladium species with low valence exhibits better combustion performance due to their stronger interaction with support. The results indicate that the galvanic deposition method is an effective route to prepare efficient catalyst for methane combustion, and it also provides useful information for improving the present commercial catalyst.展开更多
基金supported in part by the National Key R&D Program of China under Grant 2019YFB1802803in part by Beijing Municipal Natural Science Foundation under Grant L192028in part by the Nature Science Foundation of China under Grant 61801011
文摘In this work,we employ the cache-enabled UAV to provide context information delivery to end devices that make timely and intelligent decisions.Different from the traditional network traffic,context information varies with time and brings in the ageconstrained requirement.The cached content items should be refreshed timely based on the age status to guarantee the freshness of user-received contents,which however consumes additional transmission resources.The traditional cache methods separate the caching and the transmitting,which are not suitable for the dynamic context information.We jointly design the cache replacing and content delivery based on both the user requests and the content dynamics to maximize the offloaded traffic from the ground network.The problem is formulated based on the Markov Decision Process(MDP).A sufficient condition of cache replacing is found in closed form,whereby a dynamic cache replacing and content delivery scheme is proposed based on the Deep Q-Network(DQN).Extensive simulations have been conducted.Compared with the conventional popularity-based and the modified Least Frequently Used(i.e.,LFU-dynamic)schemes,the UAV can offload around 30%traffic from the ground network by utilizing the proposed scheme in the urban scenario,according to the simulation results.
文摘With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an important measurement in new trade protectionism. This article analyzes the replacement of TBT on tariff barrier for exporting countries, as well as the trading pattern of TBT in its maturing period through the discussion of macro strategies of surpassing TBT; meanwhile it also probes into the examination and supervision policies of governmental functional departments.
文摘In the Acknowledgments Section,please replace“Shell oil”for“TotalEnergies”.The authors would like to apologise for any inconvenience caused.For the sake of clarity(“Shell oil”should be removed and in boldblack“TotalEnergies”inserted),this section should say:The authors would like to thank Moura Batteries for the financial support.
基金financially supported by the National Natural Science Foundation of ChinaChina(Nos.22378424,22127812,U20B6005,52004136)+1 种基金the Science Foundation of China University of Petroleum,Beijing(No.2462023BJRC017)Hunan Provincial Department of Education Scientific Research Project(No.22B0310)。
文摘Since hydrate resources play a part of the stratigraphic framework structure in sediments,establishing a safe and economic method for hydrates exploitation remains the primary challenge to this day.Among the proposed methods,the spontaneous displacement of CH_(4) from hydrate cages by CO_(2) seems to be a perfect mechanism to address gas production and CO_(2) storage,especially in today's strong demand for carbon reduction and replacing clean energy.After extensive lab researches,in the past decade,injecting a mixture of CO_(2) and small molecule gas has become a key means to enhance displacement efficiency and has great potential for application.However,there is a lack of in-depth research on gas flow in the reservoir,while the injected gas always passes through low-saturated hydrate areas with high permeability and then occurs gas channel in a short term,finally resulting in the decreases in gas production efficiency and produced gas quality.Therefore,we explored a new injection-production mode of alternate injection of N2 and CO_(2) in order to fully coordinate the advantages of N_(2) in enhanced hydrate decomposition and CO_(2) in solid storage and heat compensation.These alternate"taking"and"storing"processes perfectly repair the problem of the gas channel,achieving self-regulation effect of CH_(4) recovery and CO_(2) storage.The 3-D experimental results show that compared to the mixed gas injection,CH_(4) recovery is increased by>50%and CO_(2) storage is increased by>70%.Additionally,this alternate injection mode presented a better performance in CH_(4) concentration of produced gas and showed outstanding N_(2) utilization efficiency.Further,we analyzed its self-adaptive gas flow mechanism and proposed an application model of"one injection and multiple production".We look forward to this study accelerating the application of CO_(2)-CH_(4) replacement technology.
文摘A notable portion of cachelines in real-world workloads exhibits inner non-uniform access behaviors.However,modern cache management rarely considers this fine-grained feature,which impacts the effective cache capacity of contemporary high-performance spacecraft processors.To harness these non-uniform access behaviors,an efficient cache replacement framework featuring an auxiliary cache specifically designed to retain evicted hot data was proposed.This framework reconstructs the cache replacement policy,facilitating data migration between the main cache and the auxiliary cache.Unlike traditional cacheline-granularity policies,the approach excels at identifying and evicting infrequently used data,thereby optimizing cache utilization.The evaluation shows impressive performance improvement,especially on workloads with irregular access patterns.Benefiting from fine granularity,the proposal achieves superior storage efficiency compared with commonly used cache management schemes,providing a potential optimization opportunity for modern resource-constrained processors,such as spacecraft processors.Furthermore,the framework complements existing modern cache replacement policies and can be seamlessly integrated with minimal modifications,enhancing their overall efficacy.
基金funded by a University College Dublin Career Development Award(ref.SF1881).
文摘To the editor:Psychiatric theory,policy and practice are currently grappling with the risks and opportunities presented by artificial intelligence(AI)applications in mental healthcare.Synthesising data to generate diagnosis is an aspect of mental healthcare where AI is anticipated to have the greatest and soonest impact.1-4 While such technologies remain some distance from clinical application,preliminary evidence suggests AI-derived classifications may predict certain treatment outcomes and clinical trajectories,and could soon become available to supplement or replace traditional manual-based diagnostic assessment.
文摘Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to medical complexity,ethical conflicts,and decision dilemmas in intensive care unit(ICU)settings.This study aimed to develop a decision aid(DA)for the family surrogate of critically ill patients to support their engagement in shared decision-making process with clinicians.Methods Development of DA employed a systematic process with user-centered design(UCD)principle,which included:(i)competitive analysis:searched,screened,and assessed the existing DAs to gather insights for design strategies,developmental techniques,and functionalities;(ii)user needs assessment:interviewed family surrogates in our hospital to explore target user group's decision-making experience and identify their unmet needs;(iii)evidence syntheses:integrate latest clinical evidence and pertinent information to inform the content development of DA.Results The competitive analysis included 16 relevant DAs,from which we derived valuable insights using existing resources.User decision needs were explored among a cohort of 15 family surrogates,revealing four thematic issues in decision-making,including stuck into dilemmas,sense of uncertainty,limited capacity,and delayed decision confirmation.A total of 27 articles were included for evidence syntheses.Relevant decision making knowledge on disease and treatment,as delineated in the literature sourced from decision support system or clinical guidelines,were formatted as the foundational knowledge base.Twenty-one items of evidence were extracted and integrated into the content panels of benefits and risks of RRT,possible outcomes,and reasons to choose.The DA was drafted into a web-based phototype using the elements of UCD.This platform could guide users in their preparation of decision-making through a sequential four-step process:identifying treatment options,weighing the benefits and risks,clarifying personal preferences and values,and formulating a schedule for formal shared decision-making with clinicians.Conclusions We developed a rapid prototype of DA tailored for family surrogate decision makers of critically ill patients in need of RRT in ICU setting.Future studies are needed to evaluate its usability,feasibility,and clinical effects of this intervention.
基金supported by the National Natural Science Foundation of China (No.82170375 & No.8210 2129 & U23A20395)the 1·3·5 Project for Disciplines of Excellence from West China Hospital of Sichuan University (ZYGD23021)the Sichuan Science and Technology Program (No.2024NSFSC1714 & No.2024 NSFSC1716).
文摘Background Epicardial adipose tissue(EAT)radiomics derived from cardiac computed tomography(CT)images may pr-ovide insights into EAT characteristics,which can further predict regression of left ventricular mass index(LVMI)after transcath-eter aortic valve replacement(TAVR).This study aimed to develop and validate a radiomics nomogram based on pre-procedural EAT CT to predict inadequate LVMI regression following TAVR.Methods Inadequate LVMI regression was defined asΔLVMI%<15%at one-year post TAVR.Radiomics features from pre-procedural CT images were selected mainly by least absolute shrinkage and selection operator algorithm.The patients were ran-domly divided into the training and validation cohorts to establish and evaluate three feature classifier models based on the selec-ted features,using which the Radiomics scores(Radscores)were then calculated.A radiomics nomogram was constructed using independent risk factors and further assessed using area under the curve,calibration curve,and decision curve analysis.Results A total of 144 consecutive TAVR patients(42 patients with inadequate and 102 patients with adequate LVMI regres-sion)were randomly assigned to the training and validation cohorts(116 patients and 28 patients,respectively).A total of 1130 radiomics features from each patient yielded 6 features for the Radscore construction after selection,with logistic regression and support vector machine models favored.Subsequently,a nomogram based solely on the Radscore was constructed,with an area under the curve of 0.743 in the validation cohort,along with favorable decision curve analysis and calibration curves.Conclusions The developed radiomics nomogram,serving as a non-invasive tool,achieved satisfactory preoperative predic-tion of inadequate LVMI regression in TAVR patients,thereby facilitating clinical management.
文摘项目时间Project Period:2003-Now项目采用了置换与填充的规划思路,逐步添加改造,或延伸、或包裹、或渗入现有肌理,创造了一层新的相贯通的公共空间和设施。都市实践总体控制与使用者个性发挥的互动十分符合创意产业和厂房改造的特点。The main strategies of this project are replacing
文摘With the prevalence of MOOCs,a heated discussion is raised about whether it can replace the traditional courses.This paper addresses the advantages of MOOCs and disadvantages of it in the English courses and answers the heated issue.
文摘Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT.Regional citrate anticoagulation(RCA)has been shown to potentially be safer and more effective,and is now recommended as the preferred anticoagulant method for CRRT.However,there is still a lack of unified standards for RCA management in the world,and there are many problems in using this method in clinical practice.The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association(CMDA)organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues,including the advantages and disadvantages of RCA in CRRT anticoagulation,the principle of RCA,parameter settings for RCA,monitoring of RCA(mainly metabolic acid-base disorders),and special issues during RCA.Based on the latest available research evidence as well as the paneled experts'clinical experience,considering the generalizability,suitability,and potential resource utilization,while also balancing clinical advantages and disadvantages,a total of 16 guideline recommendations were formed from the experts'consensus.
基金supported by the National Natural Science Foundation of China (21273221)the National High Technology Research and Development Program of China (863 Program, 2011AA03A406)
文摘Galvanic deposition method was used to prepare the Pd/Ni-Al2O3-GD catalyst for the combustion of methane under lean conditions. The new catalyst and compared catalysts （Pd/Al2O3-IW, Pd-Ni/Al2O3-IW, Pd/Ni-Al2O3-IW） prepared by incipient wetness impregnation were characterized by N2-physisorption, XRD and TEM to clarify particle size and size distribution of palladium species. Combined O2-TPD and XPS results with the catalytic data, it shows that the surface palladium species with low valence exhibits better combustion performance due to their stronger interaction with support. The results indicate that the galvanic deposition method is an effective route to prepare efficient catalyst for methane combustion, and it also provides useful information for improving the present commercial catalyst.
