Epidemiological studies showed that night workers are at higher risk of developing chronic metabolic diseases.However,no study has investigated the changes in circadian rhythms caused by a combined effect of sleep and...Epidemiological studies showed that night workers are at higher risk of developing chronic metabolic diseases.However,no study has investigated the changes in circadian rhythms caused by a combined effect of sleep and diet in a real-life setting on cardiometabolic health,gut microbiota,and psychological status in healthy people.A 4-week step-wise misaligned-realigned controlled-feeding trial with a 2×2 factorial design(sleep and diet)was conducted on healthy young adults.At first,subjects experienced a one-week circadian rhythm misalignment with a high-fat fast-food diet,extended eating window,and delayed sleep schedules,then gradually transited to a complete circadian rhythm realignment with a high-fiber balanced diet,8-h timerestricted eating,and normal sleep schedules.Circadian rhythm misalignment led to significantly higher levels of fasting glucose and homeostatic model assessment for insulin resistance(HOMA-IR)of subjects compared to baseline and failed to recover to the baseline level in circadian rhythm realignments.Notably,the incremental area under the curve(iAUC)of postprandial glucose decreased with circadian rhythm adjustments as compared to that in circadian rhythm misalignment,suggesting circadian rhythm realignment by sleep or/and diet could partly restore glucose metabolism impaired by a short-term circadian rhythm misalignment.However,circadian rhythm changes did not result in overall perturbations of gut microbiota diversities.展开更多
The multiple-input multiple-output(MIMO)-enabled beamforming technology offers great data rate and channel quality for next-generation communication.In this paper,we propose a beam channel model and enable it with tim...The multiple-input multiple-output(MIMO)-enabled beamforming technology offers great data rate and channel quality for next-generation communication.In this paper,we propose a beam channel model and enable it with time-varying simulation capability by adopting the stochastic geometry theory.First,clusters are generated located within transceivers'beam ranges based on the Mate?rn hardcore Poisson cluster process.The line-of-sight,singlebounce,and double-bounce components are calculated when generating the complex channel impulse response.Furthermore,we elaborate on the expressions of channel links based on the propagation-graph theory.A birth-death process consisting of the effects of beams and cluster velocities is also formulated.Numerical simulation results prove that the proposed model can capture the channel non-stationarity.Besides,the non-reciprocal beam patterns yield severe channel dispersion compared to the reciprocal patterns.展开更多
The formation of spatial patterns is an important issue in reaction–diffusion systems.Previous studies have mainly focused on the spatial patterns in reaction–diffusion models equipped with symmetric diffusion(such ...The formation of spatial patterns is an important issue in reaction–diffusion systems.Previous studies have mainly focused on the spatial patterns in reaction–diffusion models equipped with symmetric diffusion(such as normal or fractional Laplace diffusion),namely,assuming that spatial environments of the systems are homogeneous.However,the complexity and heterogeneity of spatial environments of biochemical reactions in vivo can lead to asymmetric diffusion of reactants.Naturally,there arises an open question of how the asymmetric diffusion affects dynamical behaviors of biochemical reaction systems.To answer this,we build a general asymmetric L´evy diffusion model based on the theory of a continuous time random walk.In addition,we investigate the two-species Brusselator model with asymmetric L´evy diffusion,and obtain a general condition for the formation of Turing and wave patterns.More interestingly,we find that even though the Brusselator model with symmetric diffusion cannot produce steady spatial patterns for some parameters,the asymmetry of L´evy diffusion for this model can produce wave patterns.This is different from the previous result that wave instability requires at least a three-species model.In addition,the asymmetry of L´evy diffusion can significantly affect the amplitude and frequency of the spatial patterns.Our results enrich our knowledge of the mechanisms of pattern formation.展开更多
This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and infants.We recruited 150 lactating women at 1-month postpartum.The esti...This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and infants.We recruited 150 lactating women at 1-month postpartum.The estimated bone mineral density(eBMD)of subjects’calcanei and the information on dietary intake were collected.After 5-month follow-up,the eBMD of mothers and their infants were measured again.Factor analysis was applied to determine maternal DPs.General linear models were used to evaluate the association between maternal DPs and maternal eBMD loss or infants’eBMD.With all potential covariates adjusted,Factor 2(high intake of whole grains,tubers,mixed beans,soybeans and soybean products,seaweeds,and nuts)showed a positive association with the changes of maternal eBMD(β=0.16,95%CI:0.005,0.310).Factor 3(high intake of soft drinks,fried foods,and puffed foods)was inversely correlated with the changes of maternal eBMD(β=-0.22,95%CI:-0.44,0.00).The changes of maternal eBMD were positively associated with 6-month infants’eBMD(β=0.34,95%CI:0.017,0.652).In conclusion,Factor 2 might contribute to the maintenance of eBMD in lactating women,while Factor 3 could exacerbate maternal eBMD loss.Additionally,the changes of maternal eBMD presented a positive correlation with 6-month infants’eBMD.展开更多
Memristors are extensively used to estimate the external electromagnetic stimulation and synapses for neurons.In this paper,two distinct scenarios,i.e.,an ideal memristor serves as external electromagnetic stimulation...Memristors are extensively used to estimate the external electromagnetic stimulation and synapses for neurons.In this paper,two distinct scenarios,i.e.,an ideal memristor serves as external electromagnetic stimulation and a locally active memristor serves as a synapse,are formulated to investigate the impact of a memristor on a two-dimensional Hindmarsh-Rose neuron model.Numerical simulations show that the neuronal models in different scenarios have multiple burst firing patterns.The introduction of the memristor makes the neuronal model exhibit complex dynamical behaviors.Finally,the simulation circuit and DSP hardware implementation results validate the physical mechanism,as well as the reliability of the biological neuron model.展开更多
Positional information encoded in spatial concentration patterns is crucial for the development of multicellular organisms.However,it is still unclear how such information is affected by the physically dissipative dif...Positional information encoded in spatial concentration patterns is crucial for the development of multicellular organisms.However,it is still unclear how such information is affected by the physically dissipative diffusion process.Here we study one-dimensional patterning systems with analytical derivation and numerical simulations.We find that the diffusion constant of the patterning molecules exhibits a nonmonotonic effect on the readout of the positional information from the concentration patterns.Specifically,there exists an optimal diffusion constant that maximizes the positional information.Moreover,we find that the energy dissipation due to the physical diffusion imposes a fundamental upper limit on the positional information.展开更多
Understanding fingering, as a challenge to stable displacement during the immiscible flow, has become a crucial phenomenon for geological carbon sequestration, enhanced oil recovery, and groundwater protection. Typica...Understanding fingering, as a challenge to stable displacement during the immiscible flow, has become a crucial phenomenon for geological carbon sequestration, enhanced oil recovery, and groundwater protection. Typically governed by gravity, viscous and capillary forces, these factors lead invasive fluids to occupy pore space irregularly and incompletely. Previous studies have demonstrated capillary numbers,describing the viscous and capillary forces, to quantificationally induce evolution of invasion patterns.While the evolution mechanisms of invasive patterns have not been deeply elucidated under the constant capillary number and three variable parameters including velocity, viscosity, and interfacial tension.Our research employs two horizontal visualization systems and a two-phase laminar flow simulation to investigate the tendency of invasive pattern transition by various parameters at the pore scale. We showed that increasing invasive viscosity or reducing interfacial tension in a homogeneous pore space significantly enhanced sweep efficiency, under constant capillary number. Additionally, in the fingering crossover pattern, the region near the inlet was prone to capillary fingering with multi-directional invasion, while the viscous fingering with unidirectional invasion was more susceptible occurred in the region near the outlet. Furthermore, increasing invasive viscosity or decreasing invasive velocity and interfacial tension promoted the extension of viscous fingering from the outlet to the inlet, presenting that the subsequent invasive fluid flows toward the outlet. In the case of invasive trunk along a unidirectional path, the invasive flow increased exponentially closer to the outlet, resulting in a significant decrease in the width of the invasive interface. Our work holds promising applications for optimizing invasive patterns in heterogeneous porous media.展开更多
This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4485 elderly individual...This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey(2011−2018).Cognitive function was assessed by the Mini-mental State Examination(MMSE),and cognitive impairment was defined as an MMSE score below 18 points.Diet patterns were assessed using the overall plant-based diet index(PDI),healthful plant-based diet index(hPDI),and unhealthful plant-based diet index(uPDI)derived from a simplified food frequency questionnaire(FFQ).Blood pressure was measured through physical examination.Cox proportional hazard regression and restricted cubic spline were performed.Participants with hypertension had an increased risk of cognitive impairment compared with normal group.The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI,among participants with lower hPDI than those with higher hPDI,and among participants with higher uPDI than those with lower uPDI.A healthful PBD pattern may attenuate hypertension-induced cognitive impairment,while an unhealthful PBD pattern may exacerbate hypertensioninduced cognitive impairment in elderly.Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.展开更多
The rapid identification of planting patterns for major crops in a large irrigated district has vital importance for irrigation management,water fee collection,and crop yield estimation.In this study,the OTSU algorith...The rapid identification of planting patterns for major crops in a large irrigated district has vital importance for irrigation management,water fee collection,and crop yield estimation.In this study,the OTSU algorithm and Mean-Shift algorithm were employed to automatically determine threshold values for mapping two main rotated crop patterns at the pixel scale.A time series analysis was conducted to extract the spatial distribution of rice-wheat and wheat-maize rotations in the Chuanhang irrigation district from 2016 to 2020.The results demonstrate that both threshold segmentation algorithms are reliable in extracting the spatial distribution of the crops,with an overall accuracy exceeding 80%.Additionally,both Kappa coefficients surpass 0.7,indicating better performance by OTSU method.Over the period from 2016 to 2020,the area occupied by rice-wheat rotation cropping ranged from 12500 to 14400 hm 2;whereas wheat-maize rotation cropping exhibited smaller and more variable areas ranging from 19730 to 34070 hm 2.These findings highlight how remote sensing-based approaches can provide reliable support for rapidly and accurately identifying the spatial distribution of main crop rotation patterns within a large irrigation district.展开更多
Thought patterns and language are closely related,they are two aspect of the culture.Translation,a tool of intercultural communication,connects the different thought patterns.In this paper,a specific analysis of the l...Thought patterns and language are closely related,they are two aspect of the culture.Translation,a tool of intercultural communication,connects the different thought patterns.In this paper,a specific analysis of the limitation in translation caused by the difference is illustrated.Thus,translation is influenced deeply by the different thought patterns.The only way to get the reappearance to the culture in translation is to find out the principles of translation from the different thought patterns.展开更多
The wear patterns and wear mechanisms of solid cemented carbide are analyzed in high-speed milling of aluminum alloy. Results show that the dominant wear patterns are coating damage, crater wear, micro-chipping, break...The wear patterns and wear mechanisms of solid cemented carbide are analyzed in high-speed milling of aluminum alloy. Results show that the dominant wear patterns are coating damage, crater wear, micro-chipping, breakage, and so on. The main wear mechanisms are adhesion, diffusion and fatigue. Compared with conventional speed machining, the effect and impact of thermal-dynamical coupling field play an important role in the cutting tool wear in high-speed milling of aluminum alloy.展开更多
Starting from an improved mapping approach and a linear variable separation approach, a new family of exact solutions （including solitary wave solutions, periodic wave solutions and rational function solutions） with...Starting from an improved mapping approach and a linear variable separation approach, a new family of exact solutions （including solitary wave solutions, periodic wave solutions and rational function solutions） with arbitrary functions for a general （2＋1）-dimensional Korteweg de solutions, we obtain some novel dromion-lattice solitons, system Vries system （GKdV） is derived. According to the derived complex wave excitations and chaotic patterns for the GKdV展开更多
Climate change significantly impacts forest ecosystems in arid and semi-arid regions.However,spatiotemporal patterns of climate-sensitive changes in individual tree growth under increased climate warming and precipita...Climate change significantly impacts forest ecosystems in arid and semi-arid regions.However,spatiotemporal patterns of climate-sensitive changes in individual tree growth under increased climate warming and precipitation in north-west China is unclear.The dendrochronological method was used to study climate response sensitivity of radial growth of Picea schrenkiana from 158 trees at six sites during 1990-2020.The results show that climate warming and increased precipitation significantly promoted the growth of trees.The response to temperature first increased,then decreased.However,the response to increased precipitation and the self-calibrating Palmer Drought Severity Index(scPDSI)increased significantly.In most areas of the Tianshan Mountains,the proportion of trees under increased precipitation and scPDSI positive response was relatively high.Over time,small-diameter trees were strongly affected by drought stress.It is predicted that under continuous warming and increased precipitation,trees in most areas of the Tianshan Mountains,especially those with small diameters,will be more affected by precipitation.展开更多
Studies on spatial distribution of congeneric species can supplement our understanding of species ecological processes. We analyzed population structure, spatial distribution, intra-and interspecific associations amon...Studies on spatial distribution of congeneric species can supplement our understanding of species ecological processes. We analyzed population structure, spatial distribution, intra-and interspecific associations among six Symplocos tree species on a large(50 ha) plot in a subtropical, evergreen broad-leaf forest in southern China using spatial point pattern analysis methods. Our results suggested that the six Symplocos tree species were all clustered at small scales. The aggregation intensity of S. wikstroemiifolia with low abundance but relatively numerous large-diameter trees was much higher than that of the other five Symplocos species that occurred at high abundance but included few large-diameter trees. Spatial associations among the six congeners showed that 12 of 30 pairs were associated positively at small scales, and 13 of 30 pairs were unrelated. For species among different size classes, 79 of 120 pairs were not correlated, and 17 of 120 pairs were associated positively. These results showed insufficient evidence for interspecific competition and congeneric Symplocos species commonly coexist within subtropical plant communities. The spatial patterns of Symplocos species and their correlations changed with size(DBH) class and were simultaneously affected by spatial scales; the intensity of their aggregation and association decreased with increasing area of the sample plot.展开更多
The surface wrinkling of biological tissues is ubiquitous in nature.Accumulating evidence suggests that the mechanical force plays a significant role in shaping the biological morphologies.Controlled wrinkling has bee...The surface wrinkling of biological tissues is ubiquitous in nature.Accumulating evidence suggests that the mechanical force plays a significant role in shaping the biological morphologies.Controlled wrinkling has been demonstrated to be able to spontaneously form rich multiscale patterns,on either planar or curved surfaces.The surface wrinkling on planar substrates has been investigated thoroughly during the past decades.However,most wrinkling morphologies in nature are based on the curved biological surfaces and the research of controllable patterning on curved substrates still remains weak.The study of wrinkling on curved substrates is critical for understanding the biological growth,developing threedimensional(3D)or four-dimensional(4D)fabrication techniques,and creating novel topographic patterns.In this review,fundamental wrinkling mechanics and recent advances in both fabrications and applications of the wrinkling patterns on curved substrates are summarized.The mechanics behind the wrinkles is compared between the planar and the curved cases.Beyond the film thickness,modulus ratio,and mismatch strain,the substrate curvature is one more significant parameter controlling the surface wrinkling.Curved substrates can be both solid and hollow with various 3D geometries across multiple length scales.Up to date,the wrinkling morphologies on solid/hollow core-shell spheres and cylinders have been simulated and selectively produced.Emerging applications of the curved topographic patterns have been found in smart wetting surfaces,cell culture interfaces,healthcare materials,and actuators,which may accelerate the development of artificial organs,stimuli-responsive devices,and micro/nano fabrications with higher dimensions.展开更多
We propose a compressed ghost imaging scheme based on differential speckle patterns,named CGI-DSP.In the scheme,a series of bucket detector signals are acquired when a series of random speckle patterns are employed to...We propose a compressed ghost imaging scheme based on differential speckle patterns,named CGI-DSP.In the scheme,a series of bucket detector signals are acquired when a series of random speckle patterns are employed to illuminate an unknown object.Then the differential speckle patterns(differential bucket detector signals)are obtained by taking the difference between present random speckle patterns(present bucket detector signals)and previous random speckle patterns(previous bucket detector signals).Finally,the image of object can be obtained directly by performing the compressed sensing algorithm on the differential speckle patterns and differential bucket detector signals.The experimental and simulated results reveal that CGI-DSP can improve the imaging quality and reduce the number of measurements comparing with the traditional compressed ghost imaging schemes because our scheme can remove the environmental illuminations efficiently.展开更多
The thermal-electrical characteristic of a GaN light-emitting diode （LED） with the hybrid transparent conductive layers （TCLs） of graphene （Gr） and NiOx is investigated by a finite element method. It is indicate...The thermal-electrical characteristic of a GaN light-emitting diode （LED） with the hybrid transparent conductive layers （TCLs） of graphene （Gr） and NiOx is investigated by a finite element method. It is indicated that the LED with the compound TCL of 3-layer Gr and 1 nm NiOx has the best thermal-electrical performance from the view point of the maximum temperature and the current density deviation of multiple quantum wells, and the maximum temperature occurs near the n-electrode rather than p-electrode. Furthermore, to depress the current crowding on the LED, the electrode pattern parameters including p- and n-electrode length, p-electrode buried depth and the distance of n-electrode to active area are optimized. It is found that either increasing p- or n-electrode length and buried depth or decreasing the distance of n-electrode from the active area will decrease the temperature of the LED, while the increase of the n-electrode length has more prominent effect. Typically, when the n-electrode length increases to 0.8 times of the chip size, the temperature of the GaN LED with the inm NiOx/3-1ayer-Gr hybrid TCLs could drop about 7K and the current density uniformity could increase by 23.8%, compared to 0.4 times of the chip size. This new finding will be beneficial for improvement of the thermal- electrical performance of LEDs with various conductive TCLs such as NiOx/Gr or ITO/Gr as current spreading layers.展开更多
In order to determine the planar and volume distribution of sand bodies of the Jurassic Badaowan formation in Block T13 of Junggar basin,we used analysis of field outcrop and 3D seismic data,which play an essential ro...In order to determine the planar and volume distribution of sand bodies of the Jurassic Badaowan formation in Block T13 of Junggar basin,we used analysis of field outcrop and 3D seismic data,which play an essential role in areas of sparse well coverage.We describe sedimentary facies characteristics,sand body planforms,width and connectivity patterns of sand bodies,and vertical associations and successions by acoustic impedance inversion technology and sedimentological theory.Results of our study show braided fluvial strata deposits in the Jurassic Badaowan formation.Each sand body is approximately lenticular in shape.The width of each sand body falls in the range 100～800 m,with most between 200 and 400 m.The sand bodies vary in thickness from 4 to 13 m,with most below 9 m.The width/thickness ratios lie in the range 20～55.The connectivity of braided fluvial channel sand bodies is controlled by changes of accommodation space.One fining-upward sedimentary cycle of base-level rise is recognized in Badaowan formation,representing an upward rise of base level.The connectivity of sand bodies was found to be greatest in the early stage of base-level rise,becoming progressively worse with increasing base-level rise.展开更多
The Chang 73 sub-member of Triassic Yanchang Formation in the Ordos Basin was taken as an example and the lamina types and combinations,reservoir space features and shale oil enrichment patterns in organic-rich shale ...The Chang 73 sub-member of Triassic Yanchang Formation in the Ordos Basin was taken as an example and the lamina types and combinations,reservoir space features and shale oil enrichment patterns in organic-rich shale strata were investigated using core observation,thin section analysis,XRF element measurement,XRD analysis,SEM,high solution laser Raman spectroscopy analysis,and micro-FTIR spectroscopy analysis,etc.According to the mineral composition and thickness of the laminae,the Chang 73 organic-rich shales have four major types of laminae,tuff-rich lamina,organic-rich lamina,silt-grade feldspar-quartz lamina and clay lamina.They have two kinds of shale oil-bearing layers,"organic-rich lamina+silt-grade feldspar-quartz lamina"and"organic-rich lamina+tuff-rich lamina"layers.In the"organic-rich+silt-grade feldspar-quartz"laminae combination shale strata,oil was characterized by relative high maturation,and always filled in K-feldspar dissolution pores in the silt-grade feldspar-quartz laminae,forming oil generation,migration and accumulation process between laminae inside the organic shales.In the"organic-rich+tuff-rich lamina"binary laminae combination shale strata,however,the reservoir properties were poor in organic-rich shales,the oil maturation was relatively lower,and mainly accumulated in the intergranular pores of interbedded thin-layered sandstones.The oil generation,migration and accumulation mainly occurred between organic-rich shales and interbedded thin-layered sandstones.展开更多
Objective To describe the long-term antithrombotic management patterns(AMPs)and clinical outcomes of Chinese patients with acute coronary syndrome(ACS).Methods This was an observational,multicenter,longitudinal cohort...Objective To describe the long-term antithrombotic management patterns(AMPs)and clinical outcomes of Chinese patients with acute coronary syndrome(ACS).Methods This was an observational,multicenter,longitudinal cohort extension study of Chinese patients who had completed the EPICOR Asia 2-year follow-up study post-hospitalization for an ACS event.Changes in AMP and clinical outcomes for up to 5 years post-ACS event were evaluated.Results Overall,2334 patients with ACS were enrolled at 49 sites.The mean age was 61.6 years and 76.3%were men.By study end,2093 patients completed the 3-year follow-up.At baseline(2 years post-ACS event),72.4%of patents received one antiplatelet(AP)medication,with aspirin being the preferred one.A small proportion of patients(21.5%)was treated with two or more APs(2+AP),and even fewer patients(6.1%)did not receive any AP medication at baseline.Upon study completion,the proportion of patients without AP therapy increased to 13.6%,while the percentage of patients on one AP and 2+AP decreased to 69.3%and 17.1%,respectively.Numerically,a higher incidence of clinical events(composite of all-cause mortality,myocardial infarction,stroke)was observed for the 2+AP(13.2%)subgroup than for the no AP(10.5%)and one AP(8.6%)subgroups.Furthermore,the 2+AP subgroup exhibited the greatest number of bleeding events,outpatient visits,and hospitalization rates.Unlike myocardial infarction or stroke,bleeding events prompted an adjustment in AMP.Conclusion Most patients in China received at least one AP medication up to 5 years after an ACS event.展开更多
文摘Epidemiological studies showed that night workers are at higher risk of developing chronic metabolic diseases.However,no study has investigated the changes in circadian rhythms caused by a combined effect of sleep and diet in a real-life setting on cardiometabolic health,gut microbiota,and psychological status in healthy people.A 4-week step-wise misaligned-realigned controlled-feeding trial with a 2×2 factorial design(sleep and diet)was conducted on healthy young adults.At first,subjects experienced a one-week circadian rhythm misalignment with a high-fat fast-food diet,extended eating window,and delayed sleep schedules,then gradually transited to a complete circadian rhythm realignment with a high-fiber balanced diet,8-h timerestricted eating,and normal sleep schedules.Circadian rhythm misalignment led to significantly higher levels of fasting glucose and homeostatic model assessment for insulin resistance(HOMA-IR)of subjects compared to baseline and failed to recover to the baseline level in circadian rhythm realignments.Notably,the incremental area under the curve(iAUC)of postprandial glucose decreased with circadian rhythm adjustments as compared to that in circadian rhythm misalignment,suggesting circadian rhythm realignment by sleep or/and diet could partly restore glucose metabolism impaired by a short-term circadian rhythm misalignment.However,circadian rhythm changes did not result in overall perturbations of gut microbiota diversities.
基金supported by the National Key R&D Program of China under grant 2020YFB1804901the National Natural Science Foundation of China under grant 62341102。
文摘The multiple-input multiple-output(MIMO)-enabled beamforming technology offers great data rate and channel quality for next-generation communication.In this paper,we propose a beam channel model and enable it with time-varying simulation capability by adopting the stochastic geometry theory.First,clusters are generated located within transceivers'beam ranges based on the Mate?rn hardcore Poisson cluster process.The line-of-sight,singlebounce,and double-bounce components are calculated when generating the complex channel impulse response.Furthermore,we elaborate on the expressions of channel links based on the propagation-graph theory.A birth-death process consisting of the effects of beams and cluster velocities is also formulated.Numerical simulation results prove that the proposed model can capture the channel non-stationarity.Besides,the non-reciprocal beam patterns yield severe channel dispersion compared to the reciprocal patterns.
基金supported by the National Natural Science Foundation of China(Grant Nos.62066026,62363027,and 12071408)PhD program of Entrepreneurship and Innovation of Jiangsu Province,Jiangsu University’Blue Project’,the Natural Science Foundation of Jiangxi Province(Grant No.20224BAB202026)the Science and Technology Research Project of Jiangxi Provincial Department of Education(Grant No.GJJ2203316).
文摘The formation of spatial patterns is an important issue in reaction–diffusion systems.Previous studies have mainly focused on the spatial patterns in reaction–diffusion models equipped with symmetric diffusion(such as normal or fractional Laplace diffusion),namely,assuming that spatial environments of the systems are homogeneous.However,the complexity and heterogeneity of spatial environments of biochemical reactions in vivo can lead to asymmetric diffusion of reactants.Naturally,there arises an open question of how the asymmetric diffusion affects dynamical behaviors of biochemical reaction systems.To answer this,we build a general asymmetric L´evy diffusion model based on the theory of a continuous time random walk.In addition,we investigate the two-species Brusselator model with asymmetric L´evy diffusion,and obtain a general condition for the formation of Turing and wave patterns.More interestingly,we find that even though the Brusselator model with symmetric diffusion cannot produce steady spatial patterns for some parameters,the asymmetry of L´evy diffusion for this model can produce wave patterns.This is different from the previous result that wave instability requires at least a three-species model.In addition,the asymmetry of L´evy diffusion can significantly affect the amplitude and frequency of the spatial patterns.Our results enrich our knowledge of the mechanisms of pattern formation.
基金NSFC and CNS for funding the projectfunded by the National Natural Science Foundation of China(NSFC,82173500)“CNS-ZD Tizhi and Health Fund”(CNS-ZD2020-163).
文摘This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and infants.We recruited 150 lactating women at 1-month postpartum.The estimated bone mineral density(eBMD)of subjects’calcanei and the information on dietary intake were collected.After 5-month follow-up,the eBMD of mothers and their infants were measured again.Factor analysis was applied to determine maternal DPs.General linear models were used to evaluate the association between maternal DPs and maternal eBMD loss or infants’eBMD.With all potential covariates adjusted,Factor 2(high intake of whole grains,tubers,mixed beans,soybeans and soybean products,seaweeds,and nuts)showed a positive association with the changes of maternal eBMD(β=0.16,95%CI:0.005,0.310).Factor 3(high intake of soft drinks,fried foods,and puffed foods)was inversely correlated with the changes of maternal eBMD(β=-0.22,95%CI:-0.44,0.00).The changes of maternal eBMD were positively associated with 6-month infants’eBMD(β=0.34,95%CI:0.017,0.652).In conclusion,Factor 2 might contribute to the maintenance of eBMD in lactating women,while Factor 3 could exacerbate maternal eBMD loss.Additionally,the changes of maternal eBMD presented a positive correlation with 6-month infants’eBMD.
基金supported by the National Natural Science Foundation of China(Grant No.62061014)Technological Innovation Projects in the Field of Artificial Intelligence in Liaoning province(Grant No.2023JH26/10300011)Basic Scientific Research Projects in Department of Education of Liaoning Province(Grant No.JYTZD2023021).
文摘Memristors are extensively used to estimate the external electromagnetic stimulation and synapses for neurons.In this paper,two distinct scenarios,i.e.,an ideal memristor serves as external electromagnetic stimulation and a locally active memristor serves as a synapse,are formulated to investigate the impact of a memristor on a two-dimensional Hindmarsh-Rose neuron model.Numerical simulations show that the neuronal models in different scenarios have multiple burst firing patterns.The introduction of the memristor makes the neuronal model exhibit complex dynamical behaviors.Finally,the simulation circuit and DSP hardware implementation results validate the physical mechanism,as well as the reliability of the biological neuron model.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.32271293 and 11875076)。
文摘Positional information encoded in spatial concentration patterns is crucial for the development of multicellular organisms.However,it is still unclear how such information is affected by the physically dissipative diffusion process.Here we study one-dimensional patterning systems with analytical derivation and numerical simulations.We find that the diffusion constant of the patterning molecules exhibits a nonmonotonic effect on the readout of the positional information from the concentration patterns.Specifically,there exists an optimal diffusion constant that maximizes the positional information.Moreover,we find that the energy dissipation due to the physical diffusion imposes a fundamental upper limit on the positional information.
基金supported by the National Natural Science Foundation of China Joint Fund Project (Grant/Award Number: U20B6003)National Natural Science Foundation of China (Grant/Award Number: 52304054)。
文摘Understanding fingering, as a challenge to stable displacement during the immiscible flow, has become a crucial phenomenon for geological carbon sequestration, enhanced oil recovery, and groundwater protection. Typically governed by gravity, viscous and capillary forces, these factors lead invasive fluids to occupy pore space irregularly and incompletely. Previous studies have demonstrated capillary numbers,describing the viscous and capillary forces, to quantificationally induce evolution of invasion patterns.While the evolution mechanisms of invasive patterns have not been deeply elucidated under the constant capillary number and three variable parameters including velocity, viscosity, and interfacial tension.Our research employs two horizontal visualization systems and a two-phase laminar flow simulation to investigate the tendency of invasive pattern transition by various parameters at the pore scale. We showed that increasing invasive viscosity or reducing interfacial tension in a homogeneous pore space significantly enhanced sweep efficiency, under constant capillary number. Additionally, in the fingering crossover pattern, the region near the inlet was prone to capillary fingering with multi-directional invasion, while the viscous fingering with unidirectional invasion was more susceptible occurred in the region near the outlet. Furthermore, increasing invasive viscosity or decreasing invasive velocity and interfacial tension promoted the extension of viscous fingering from the outlet to the inlet, presenting that the subsequent invasive fluid flows toward the outlet. In the case of invasive trunk along a unidirectional path, the invasive flow increased exponentially closer to the outlet, resulting in a significant decrease in the width of the invasive interface. Our work holds promising applications for optimizing invasive patterns in heterogeneous porous media.
基金supported by the National Key R&D Program of China(2018YFC2000400)the National Natural Sciences Foundation of China(72061137004)+1 种基金the National Institute on Aging of National Institutes of Health(P01AG031719)Duke/DukeNUS(grant RECA(Pilot)/2019/0051 to Y.Z.).
文摘This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey(2011−2018).Cognitive function was assessed by the Mini-mental State Examination(MMSE),and cognitive impairment was defined as an MMSE score below 18 points.Diet patterns were assessed using the overall plant-based diet index(PDI),healthful plant-based diet index(hPDI),and unhealthful plant-based diet index(uPDI)derived from a simplified food frequency questionnaire(FFQ).Blood pressure was measured through physical examination.Cox proportional hazard regression and restricted cubic spline were performed.Participants with hypertension had an increased risk of cognitive impairment compared with normal group.The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI,among participants with lower hPDI than those with higher hPDI,and among participants with higher uPDI than those with lower uPDI.A healthful PBD pattern may attenuate hypertension-induced cognitive impairment,while an unhealthful PBD pattern may exacerbate hypertensioninduced cognitive impairment in elderly.Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.
基金Jiangsu Water Science and Technology Project(2021081)。
文摘The rapid identification of planting patterns for major crops in a large irrigated district has vital importance for irrigation management,water fee collection,and crop yield estimation.In this study,the OTSU algorithm and Mean-Shift algorithm were employed to automatically determine threshold values for mapping two main rotated crop patterns at the pixel scale.A time series analysis was conducted to extract the spatial distribution of rice-wheat and wheat-maize rotations in the Chuanhang irrigation district from 2016 to 2020.The results demonstrate that both threshold segmentation algorithms are reliable in extracting the spatial distribution of the crops,with an overall accuracy exceeding 80%.Additionally,both Kappa coefficients surpass 0.7,indicating better performance by OTSU method.Over the period from 2016 to 2020,the area occupied by rice-wheat rotation cropping ranged from 12500 to 14400 hm 2;whereas wheat-maize rotation cropping exhibited smaller and more variable areas ranging from 19730 to 34070 hm 2.These findings highlight how remote sensing-based approaches can provide reliable support for rapidly and accurately identifying the spatial distribution of main crop rotation patterns within a large irrigation district.
文摘Thought patterns and language are closely related,they are two aspect of the culture.Translation,a tool of intercultural communication,connects the different thought patterns.In this paper,a specific analysis of the limitation in translation caused by the difference is illustrated.Thus,translation is influenced deeply by the different thought patterns.The only way to get the reappearance to the culture in translation is to find out the principles of translation from the different thought patterns.
文摘The wear patterns and wear mechanisms of solid cemented carbide are analyzed in high-speed milling of aluminum alloy. Results show that the dominant wear patterns are coating damage, crater wear, micro-chipping, breakage, and so on. The main wear mechanisms are adhesion, diffusion and fatigue. Compared with conventional speed machining, the effect and impact of thermal-dynamical coupling field play an important role in the cutting tool wear in high-speed milling of aluminum alloy.
基金Project supported by the National Natural Science Foundation of China （Grant No 10172056）, the Natural Science Foundation of Zhejiang Province, China （Grant No Y604106）, the Foundation of New Century 151 Talent Engineering of Zhejiang Province, the Scientific Research Foundation of Zhejiang Provincial Education Department of China （Grant No 20070568） and the Natural Science Foundation of Zhejiang Lishui University （Grant No KZ04008）.
文摘Starting from an improved mapping approach and a linear variable separation approach, a new family of exact solutions （including solitary wave solutions, periodic wave solutions and rational function solutions） with arbitrary functions for a general （2＋1）-dimensional Korteweg de solutions, we obtain some novel dromion-lattice solitons, system Vries system （GKdV） is derived. According to the derived complex wave excitations and chaotic patterns for the GKdV
基金funded by the National Natural Science Foundation of China(No.31971460 and 32271646)the National Key Research and Development Program of China(2021YFD2200401)。
文摘Climate change significantly impacts forest ecosystems in arid and semi-arid regions.However,spatiotemporal patterns of climate-sensitive changes in individual tree growth under increased climate warming and precipitation in north-west China is unclear.The dendrochronological method was used to study climate response sensitivity of radial growth of Picea schrenkiana from 158 trees at six sites during 1990-2020.The results show that climate warming and increased precipitation significantly promoted the growth of trees.The response to temperature first increased,then decreased.However,the response to increased precipitation and the self-calibrating Palmer Drought Severity Index(scPDSI)increased significantly.In most areas of the Tianshan Mountains,the proportion of trees under increased precipitation and scPDSI positive response was relatively high.Over time,small-diameter trees were strongly affected by drought stress.It is predicted that under continuous warming and increased precipitation,trees in most areas of the Tianshan Mountains,especially those with small diameters,will be more affected by precipitation.
基金supported by National Natural Science Foundation of China(31470631 and 31670630)China Postdoctoral Science Foundation Grant(2013M530892)Natural Science Foundation of Shanxi Province,China(2013011030-3)
文摘Studies on spatial distribution of congeneric species can supplement our understanding of species ecological processes. We analyzed population structure, spatial distribution, intra-and interspecific associations among six Symplocos tree species on a large(50 ha) plot in a subtropical, evergreen broad-leaf forest in southern China using spatial point pattern analysis methods. Our results suggested that the six Symplocos tree species were all clustered at small scales. The aggregation intensity of S. wikstroemiifolia with low abundance but relatively numerous large-diameter trees was much higher than that of the other five Symplocos species that occurred at high abundance but included few large-diameter trees. Spatial associations among the six congeners showed that 12 of 30 pairs were associated positively at small scales, and 13 of 30 pairs were unrelated. For species among different size classes, 79 of 120 pairs were not correlated, and 17 of 120 pairs were associated positively. These results showed insufficient evidence for interspecific competition and congeneric Symplocos species commonly coexist within subtropical plant communities. The spatial patterns of Symplocos species and their correlations changed with size(DBH) class and were simultaneously affected by spatial scales; the intensity of their aggregation and association decreased with increasing area of the sample plot.
基金financially supported by National Natural Science Foundation of China(Nos.61574172 and 31971291)Hunan Provincial Natural Science Foundation for Distinguished Young Scholars(No.14JJ1001).
文摘The surface wrinkling of biological tissues is ubiquitous in nature.Accumulating evidence suggests that the mechanical force plays a significant role in shaping the biological morphologies.Controlled wrinkling has been demonstrated to be able to spontaneously form rich multiscale patterns,on either planar or curved surfaces.The surface wrinkling on planar substrates has been investigated thoroughly during the past decades.However,most wrinkling morphologies in nature are based on the curved biological surfaces and the research of controllable patterning on curved substrates still remains weak.The study of wrinkling on curved substrates is critical for understanding the biological growth,developing threedimensional(3D)or four-dimensional(4D)fabrication techniques,and creating novel topographic patterns.In this review,fundamental wrinkling mechanics and recent advances in both fabrications and applications of the wrinkling patterns on curved substrates are summarized.The mechanics behind the wrinkles is compared between the planar and the curved cases.Beyond the film thickness,modulus ratio,and mismatch strain,the substrate curvature is one more significant parameter controlling the surface wrinkling.Curved substrates can be both solid and hollow with various 3D geometries across multiple length scales.Up to date,the wrinkling morphologies on solid/hollow core-shell spheres and cylinders have been simulated and selectively produced.Emerging applications of the curved topographic patterns have been found in smart wetting surfaces,cell culture interfaces,healthcare materials,and actuators,which may accelerate the development of artificial organs,stimuli-responsive devices,and micro/nano fabrications with higher dimensions.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11847062 and 61871234)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20180755)the Science Fund from NUPT(Grant No.NY218098).
文摘We propose a compressed ghost imaging scheme based on differential speckle patterns,named CGI-DSP.In the scheme,a series of bucket detector signals are acquired when a series of random speckle patterns are employed to illuminate an unknown object.Then the differential speckle patterns(differential bucket detector signals)are obtained by taking the difference between present random speckle patterns(present bucket detector signals)and previous random speckle patterns(previous bucket detector signals).Finally,the image of object can be obtained directly by performing the compressed sensing algorithm on the differential speckle patterns and differential bucket detector signals.The experimental and simulated results reveal that CGI-DSP can improve the imaging quality and reduce the number of measurements comparing with the traditional compressed ghost imaging schemes because our scheme can remove the environmental illuminations efficiently.
基金Supported by the Foundation of the State Key Laboratory of Mechanical Transmission of Chongqing University under Grant Nos SKLMT-KFKT-201419 and SKLM-ZZKT-2015Z16the National High-Technology Research and Development Program of China under Grant No 2015AA034801+4 种基金the National Natural Science Foundation of China under Grant Nos 11374359,11304405,11544010 and 11547305the Chongqing Education Commission Scientific Project under Grant No KJ132209the Natural Science Foundation of Chongqing under Grant Nos cstc2013jcyjA50031,cstc2015jcyjA50035 and cstc2015jcyjA1660the Fundamental Research Funds for the Central Universities under Grant Nos CDJZR14135502,CDJZR14300050,106112016CDJZR288805 and 106112015CDJXY300002the Sharing Fund of Large-scale Equipment of Chongqing University under Grant Nos 201512150017,201512150029 and 201512150030
文摘The thermal-electrical characteristic of a GaN light-emitting diode （LED） with the hybrid transparent conductive layers （TCLs） of graphene （Gr） and NiOx is investigated by a finite element method. It is indicated that the LED with the compound TCL of 3-layer Gr and 1 nm NiOx has the best thermal-electrical performance from the view point of the maximum temperature and the current density deviation of multiple quantum wells, and the maximum temperature occurs near the n-electrode rather than p-electrode. Furthermore, to depress the current crowding on the LED, the electrode pattern parameters including p- and n-electrode length, p-electrode buried depth and the distance of n-electrode to active area are optimized. It is found that either increasing p- or n-electrode length and buried depth or decreasing the distance of n-electrode from the active area will decrease the temperature of the LED, while the increase of the n-electrode length has more prominent effect. Typically, when the n-electrode length increases to 0.8 times of the chip size, the temperature of the GaN LED with the inm NiOx/3-1ayer-Gr hybrid TCLs could drop about 7K and the current density uniformity could increase by 23.8%, compared to 0.4 times of the chip size. This new finding will be beneficial for improvement of the thermal- electrical performance of LEDs with various conductive TCLs such as NiOx/Gr or ITO/Gr as current spreading layers.
基金Financial support for this work,provided by the National Basic Research Program of China(No.2006 CB202300),
文摘In order to determine the planar and volume distribution of sand bodies of the Jurassic Badaowan formation in Block T13 of Junggar basin,we used analysis of field outcrop and 3D seismic data,which play an essential role in areas of sparse well coverage.We describe sedimentary facies characteristics,sand body planforms,width and connectivity patterns of sand bodies,and vertical associations and successions by acoustic impedance inversion technology and sedimentological theory.Results of our study show braided fluvial strata deposits in the Jurassic Badaowan formation.Each sand body is approximately lenticular in shape.The width of each sand body falls in the range 100～800 m,with most between 200 and 400 m.The sand bodies vary in thickness from 4 to 13 m,with most below 9 m.The width/thickness ratios lie in the range 20～55.The connectivity of braided fluvial channel sand bodies is controlled by changes of accommodation space.One fining-upward sedimentary cycle of base-level rise is recognized in Badaowan formation,representing an upward rise of base level.The connectivity of sand bodies was found to be greatest in the early stage of base-level rise,becoming progressively worse with increasing base-level rise.
基金Supported by the National Natural Fund Petrochemical Joint Fund Key Project(U1762217)Fundamental Scientific Research Operations Project of China Central Universities(19CX02009A)
文摘The Chang 73 sub-member of Triassic Yanchang Formation in the Ordos Basin was taken as an example and the lamina types and combinations,reservoir space features and shale oil enrichment patterns in organic-rich shale strata were investigated using core observation,thin section analysis,XRF element measurement,XRD analysis,SEM,high solution laser Raman spectroscopy analysis,and micro-FTIR spectroscopy analysis,etc.According to the mineral composition and thickness of the laminae,the Chang 73 organic-rich shales have four major types of laminae,tuff-rich lamina,organic-rich lamina,silt-grade feldspar-quartz lamina and clay lamina.They have two kinds of shale oil-bearing layers,"organic-rich lamina+silt-grade feldspar-quartz lamina"and"organic-rich lamina+tuff-rich lamina"layers.In the"organic-rich+silt-grade feldspar-quartz"laminae combination shale strata,oil was characterized by relative high maturation,and always filled in K-feldspar dissolution pores in the silt-grade feldspar-quartz laminae,forming oil generation,migration and accumulation process between laminae inside the organic shales.In the"organic-rich+tuff-rich lamina"binary laminae combination shale strata,however,the reservoir properties were poor in organic-rich shales,the oil maturation was relatively lower,and mainly accumulated in the intergranular pores of interbedded thin-layered sandstones.The oil generation,migration and accumulation mainly occurred between organic-rich shales and interbedded thin-layered sandstones.
基金provided by Isuru Wijesoma from MediTech Media(Singapore),which was funded by AstraZeneca in accordance with Good Publication Practice(GPP3)guidelines。
文摘Objective To describe the long-term antithrombotic management patterns(AMPs)and clinical outcomes of Chinese patients with acute coronary syndrome(ACS).Methods This was an observational,multicenter,longitudinal cohort extension study of Chinese patients who had completed the EPICOR Asia 2-year follow-up study post-hospitalization for an ACS event.Changes in AMP and clinical outcomes for up to 5 years post-ACS event were evaluated.Results Overall,2334 patients with ACS were enrolled at 49 sites.The mean age was 61.6 years and 76.3%were men.By study end,2093 patients completed the 3-year follow-up.At baseline(2 years post-ACS event),72.4%of patents received one antiplatelet(AP)medication,with aspirin being the preferred one.A small proportion of patients(21.5%)was treated with two or more APs(2+AP),and even fewer patients(6.1%)did not receive any AP medication at baseline.Upon study completion,the proportion of patients without AP therapy increased to 13.6%,while the percentage of patients on one AP and 2+AP decreased to 69.3%and 17.1%,respectively.Numerically,a higher incidence of clinical events(composite of all-cause mortality,myocardial infarction,stroke)was observed for the 2+AP(13.2%)subgroup than for the no AP(10.5%)and one AP(8.6%)subgroups.Furthermore,the 2+AP subgroup exhibited the greatest number of bleeding events,outpatient visits,and hospitalization rates.Unlike myocardial infarction or stroke,bleeding events prompted an adjustment in AMP.Conclusion Most patients in China received at least one AP medication up to 5 years after an ACS event.
