The order-of-addition experiments are widely used in many fields,including food and industrial production,but the relative research under prior constraints is limited.The purpose of this paper is to select an optimal ...The order-of-addition experiments are widely used in many fields,including food and industrial production,but the relative research under prior constraints is limited.The purpose of this paper is to select an optimal sequence under the restriction that component i is added before component j,while it is unachievable to compare all sequences when the number of components m is large.To achieve this,a constrained PWO model is first provided,and then the D-optimal designs for order-of addition experiments with minimal-points via the modified threshold accepting algorithm is established.The effectiveness of the proposed method is demonstrated through a job scheduling problem with a prior constraint for teaching cases.展开更多
To improve antagonistic metabolites production of Bacillus subtilis strain BS501a, physical parameters of fermentation and metal inorganic salts in medium, namely initial pH value, culture temperature, fermentation ti...To improve antagonistic metabolites production of Bacillus subtilis strain BS501a, physical parameters of fermentation and metal inorganic salts in medium, namely initial pH value, culture temperature, fermentation time, concentrations of CaC12, FeSO4, ZnSO4, MnSO4 and MgSO4, were optimized using one-factor-at-a-time and orthogonal tests. The results show that the optimal physical parameters of fermentation are an initial pH of 7.0, a culture temperature of 30 ~C, and a fermentation time of 48 h. The optimal concentrations of metal inorganic salts in basal medium are 10.2 mmol/L CaCl2, 0.4 mmol/L FeSO4, 3.5 mmol/L ZnSO4, 0.6 mmol/L MnSO4 and 2.0 mmol/L MgSO4. Among the metal inorganic salts, MgSO4 and MnSO4 play important roles in the improvement of the antagonistic metabolites production of B. subtilis strain BS501a; especially, MgSO4 contributes a highly significant effect. The average diameter of inhibition zone of the BS501a filtered fermentation supernatant (FFS) cultured in the optimal fermentation conditions against Magnaporthe grisea DWBJ329 reaches 71.4 mm, and there is 2.4-fold increase in antifungal activity as compared with 21.2 mm under the pre-optimized conditions.展开更多
Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combin...Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combinations of controllable parameters(microhardness and clad thickness).The microhardness and clad thickness are recorded at all the experimental runs and studied using Taguchi S/N ratio and the optimum controllable parametric combination is obtained.However,an artificial neural network(ANN)identifies different sets of optimal combinations from Taguchi method but they both got almost the same clad thickness and hardness values.The micro-hardness of cladded layer is found to be6.22 times(HV_(0.5)752)the SS304 hardness(HV_(0.5)121).The presence of nitride ceramics results in a higher micro hardness.The cladded surface is free from cracks and pores.The average clad thickness is found to be around 0.6 mm.展开更多
基金supported by National Natural Science Foundation of China(Grant Nos.11971204,12271270)Natural Science Foundation of Jiangsu Province of China(Grant No.BK20200108)the Zhongwu Youth Innovative Talent Program of Jiangsu University of Technology and the Third Level Training Object of the Sixth“333 Project”in Jiangsu Province。
文摘The order-of-addition experiments are widely used in many fields,including food and industrial production,but the relative research under prior constraints is limited.The purpose of this paper is to select an optimal sequence under the restriction that component i is added before component j,while it is unachievable to compare all sequences when the number of components m is large.To achieve this,a constrained PWO model is first provided,and then the D-optimal designs for order-of addition experiments with minimal-points via the modified threshold accepting algorithm is established.The effectiveness of the proposed method is demonstrated through a job scheduling problem with a prior constraint for teaching cases.
基金Project(2010A210003) supported by Henan Province Natural Sciences Research PlanProject(0910SGYS34370-2) supported by Zhengzhou City Science and Technology Research PlanProject supported by the Youth Backbone Teacher of Universities in Henan Province Grants Plan
文摘To improve antagonistic metabolites production of Bacillus subtilis strain BS501a, physical parameters of fermentation and metal inorganic salts in medium, namely initial pH value, culture temperature, fermentation time, concentrations of CaC12, FeSO4, ZnSO4, MnSO4 and MgSO4, were optimized using one-factor-at-a-time and orthogonal tests. The results show that the optimal physical parameters of fermentation are an initial pH of 7.0, a culture temperature of 30 ~C, and a fermentation time of 48 h. The optimal concentrations of metal inorganic salts in basal medium are 10.2 mmol/L CaCl2, 0.4 mmol/L FeSO4, 3.5 mmol/L ZnSO4, 0.6 mmol/L MnSO4 and 2.0 mmol/L MgSO4. Among the metal inorganic salts, MgSO4 and MnSO4 play important roles in the improvement of the antagonistic metabolites production of B. subtilis strain BS501a; especially, MgSO4 contributes a highly significant effect. The average diameter of inhibition zone of the BS501a filtered fermentation supernatant (FFS) cultured in the optimal fermentation conditions against Magnaporthe grisea DWBJ329 reaches 71.4 mm, and there is 2.4-fold increase in antifungal activity as compared with 21.2 mm under the pre-optimized conditions.
文摘Laser cladding of powder mixture of TiN and SS304 is carried out on an SS304 substrate with the help of fibre laser.The experiments are performed on SS304,as per the Taguchi orthogonal array(L^(16))by different combinations of controllable parameters(microhardness and clad thickness).The microhardness and clad thickness are recorded at all the experimental runs and studied using Taguchi S/N ratio and the optimum controllable parametric combination is obtained.However,an artificial neural network(ANN)identifies different sets of optimal combinations from Taguchi method but they both got almost the same clad thickness and hardness values.The micro-hardness of cladded layer is found to be6.22 times(HV_(0.5)752)the SS304 hardness(HV_(0.5)121).The presence of nitride ceramics results in a higher micro hardness.The cladded surface is free from cracks and pores.The average clad thickness is found to be around 0.6 mm.