采用液相色谱-串联质谱法(Liquid Chromatography Tandem Mass Spectrometry,LC-MS/MS)对不同品种和产地的大米中香兰素含量进行了测定和分析。本实验通过比较9种大米的香兰素含量,分析品种和产地对香兰素含量的影响,并探究不同储存条...采用液相色谱-串联质谱法(Liquid Chromatography Tandem Mass Spectrometry,LC-MS/MS)对不同品种和产地的大米中香兰素含量进行了测定和分析。本实验通过比较9种大米的香兰素含量,分析品种和产地对香兰素含量的影响,并探究不同储存条件下香兰素含量的变化。结果表明,籼稻品种的香兰素含量普遍高于粳稻品种,不同产地大米的香兰素含量存在明显差异,且储存条件对香兰素含量的保持有一定影响。本研究为大米品质评估和储存管理提供了科学依据。展开更多
A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-MS/MS) method for the simultaneous determination of aspirin (ASA) and its metabolite salicylic acid (SA) in human plasma has been...A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-MS/MS) method for the simultaneous determination of aspirin (ASA) and its metabolite salicylic acid (SA) in human plasma has been developed and validated.The plasma ASA and SA were extracted using a liquid-liquid extraction (LLE) and the sample extract was injected onto the LC-MS/MS system.The limits of quantitation(LLOQ) for ASA and SA are both 25 ng/mL.This method allowed the reproducible and accurate quantification with the concentration rang of 25-10 000 ng/mL.This method could be applied to the quantitation aspirin and salicylic acid in human plasma.展开更多
文摘采用液相色谱-串联质谱法(Liquid Chromatography Tandem Mass Spectrometry,LC-MS/MS)对不同品种和产地的大米中香兰素含量进行了测定和分析。本实验通过比较9种大米的香兰素含量,分析品种和产地对香兰素含量的影响,并探究不同储存条件下香兰素含量的变化。结果表明,籼稻品种的香兰素含量普遍高于粳稻品种,不同产地大米的香兰素含量存在明显差异,且储存条件对香兰素含量的保持有一定影响。本研究为大米品质评估和储存管理提供了科学依据。
文摘A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-MS/MS) method for the simultaneous determination of aspirin (ASA) and its metabolite salicylic acid (SA) in human plasma has been developed and validated.The plasma ASA and SA were extracted using a liquid-liquid extraction (LLE) and the sample extract was injected onto the LC-MS/MS system.The limits of quantitation(LLOQ) for ASA and SA are both 25 ng/mL.This method allowed the reproducible and accurate quantification with the concentration rang of 25-10 000 ng/mL.This method could be applied to the quantitation aspirin and salicylic acid in human plasma.
