目的探讨血清涎液化糖链抗原-6(Krebs von den Lungen-6,KL-6)、血管性血友病因子(von Willebrand factor,vWF)和白介素8(interleukin-8,IL-8)在儿童急性呼吸窘迫综合征(pediatric acute respiratory distress syndrome,pARDS)早期识别...目的探讨血清涎液化糖链抗原-6(Krebs von den Lungen-6,KL-6)、血管性血友病因子(von Willebrand factor,vWF)和白介素8(interleukin-8,IL-8)在儿童急性呼吸窘迫综合征(pediatric acute respiratory distress syndrome,pARDS)早期识别中的临床预测价值。方法纳入2023年11月-2024年11月于郑州大学第三附属医院儿童重症医学科接受机械通气治疗的患儿92例,依据患儿在明确病因损害后的7 d内是否发展为pARDS,将患儿分为pARDS组(n=35)和非pARDS组(n=57)。pARDS组分别于机械通气开始(T_(1))时、确诊pARDS(T_(2))时和确诊后第3天(T_(3)),非pARDS组于T_(1)时,采用酶联免疫吸附法检测血清标志物水平,收集并分析相关临床数据。结果T_(1)时pARDS组KL-6、vWF和IL-8水平高于非pARDS组(P<0.05)。pARDS组KL-6、vWF和IL-8水平在不同时间点的变化差异有统计学意义(P<0.05);KL-6水平在T_(2)时高于T_(1),且在T_(3)时达到研究期间峰值(P<0.01);IL-8和vWF水平在T_(2)达到峰值后于T_(3)有所下降(P<0.05)。受试者工作特征曲线分析显示,KL-6、IL-8和vWF的曲线下面积分别为0.749、0.662和0.631,三者联合检测的曲线下面积为0.776(P<0.05),对应的敏感度分别为74.3%、62.9%、62.9%和85.7%,特异度分别为82.5%、61.4%、68.4%和63.2%。结论血清KL-6、IL-8及vWF水平升高可作为pARDS早期识别的有效生物标志物,三者联合检测可提高诊断效率。展开更多
In this article, we give the sufficient and necessary conditions for which several important mapping spaces are weak＊ dense in the corresponding completely bound mapping spaces.
The selection of dens of Vulpes corsac% was investigated at Xinbaerhu Youqi in Inner Mongolia Autonomous Region, China. The result showed that the main factors notably influence on den habitats of %V. corsac% were hum...The selection of dens of Vulpes corsac% was investigated at Xinbaerhu Youqi in Inner Mongolia Autonomous Region, China. The result showed that the main factors notably influence on den habitats of %V. corsac% were human disturbance and water resource. The table of frequency and dentrogram indicated that the suitable habitat of %V. corsac’s% dens was: the flat grassland, hillside, and small hills with the distance from the water ≤1 000 m, from the human disturbance ≥1 000 m. the main resource of %V. corsac% is the scrap dens of %Marmola bobak.%展开更多
基金Project partially supported by the National Natural Science Foundation of China (10871174,10801119)
文摘In this article, we give the sufficient and necessary conditions for which several important mapping spaces are weak＊ dense in the corresponding completely bound mapping spaces.
文摘The selection of dens of Vulpes corsac% was investigated at Xinbaerhu Youqi in Inner Mongolia Autonomous Region, China. The result showed that the main factors notably influence on den habitats of %V. corsac% were human disturbance and water resource. The table of frequency and dentrogram indicated that the suitable habitat of %V. corsac’s% dens was: the flat grassland, hillside, and small hills with the distance from the water ≤1 000 m, from the human disturbance ≥1 000 m. the main resource of %V. corsac% is the scrap dens of %Marmola bobak.%
