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Research on Euclidean Algorithm and Reection on Its Teaching
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作者 ZHANG Shaohua 《应用数学》 北大核心 2025年第1期308-310,共3页
In this paper,we prove that Euclid's algorithm,Bezout's equation and Divi-sion algorithm are equivalent to each other.Our result shows that Euclid has preliminarily established the theory of divisibility and t... In this paper,we prove that Euclid's algorithm,Bezout's equation and Divi-sion algorithm are equivalent to each other.Our result shows that Euclid has preliminarily established the theory of divisibility and the greatest common divisor.We further provided several suggestions for teaching. 展开更多
关键词 Euclid's algorithm division algorithm Bezout's equation
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An Algorithm for Cloud-based Web Service Combination Optimization Through Plant Growth Simulation
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作者 Li Qiang Qin Huawei +1 位作者 Qiao Bingqin Wu Ruifang 《系统仿真学报》 北大核心 2025年第2期462-473,共12页
In order to improve the efficiency of cloud-based web services,an improved plant growth simulation algorithm scheduling model.This model first used mathematical methods to describe the relationships between cloud-base... In order to improve the efficiency of cloud-based web services,an improved plant growth simulation algorithm scheduling model.This model first used mathematical methods to describe the relationships between cloud-based web services and the constraints of system resources.Then,a light-induced plant growth simulation algorithm was established.The performance of the algorithm was compared through several plant types,and the best plant model was selected as the setting for the system.Experimental results show that when the number of test cloud-based web services reaches 2048,the model being 2.14 times faster than PSO,2.8 times faster than the ant colony algorithm,2.9 times faster than the bee colony algorithm,and a remarkable 8.38 times faster than the genetic algorithm. 展开更多
关键词 cloud-based service scheduling algorithm resource constraint load optimization cloud computing plant growth simulation algorithm
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Multi-QoS routing algorithm based on reinforcement learning for LEO satellite networks 被引量:1
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作者 ZHANG Yifan DONG Tao +1 位作者 LIU Zhihui JIN Shichao 《Journal of Systems Engineering and Electronics》 2025年第1期37-47,共11页
Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To sa... Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To satisfy quality of service(QoS)requirements of various users,it is critical to research efficient routing strategies to fully utilize satellite resources.This paper proposes a multi-QoS information optimized routing algorithm based on reinforcement learning for LEO satellite networks,which guarantees high level assurance demand services to be prioritized under limited satellite resources while considering the load balancing performance of the satellite networks for low level assurance demand services to ensure the full and effective utilization of satellite resources.An auxiliary path search algorithm is proposed to accelerate the convergence of satellite routing algorithm.Simulation results show that the generated routing strategy can timely process and fully meet the QoS demands of high assurance services while effectively improving the load balancing performance of the link. 展开更多
关键词 low Earth orbit(LEO)satellite network reinforcement learning multi-quality of service(QoS) routing algorithm
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Temperature control for liquid-cooled fuel cells based on fuzzy logic and variable-gain generalized supertwisting algorithm
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作者 CHEN Lin JIA Zhi-huan +1 位作者 DING Tian-wei GAO Jin-wu 《控制理论与应用》 北大核心 2025年第8期1596-1605,共10页
The liquid cooling system(LCS)of fuel cells is challenged by significant time delays,model uncertainties,pump and fan coupling,and frequent disturbances,leading to overshoot and control oscillations that degrade tempe... The liquid cooling system(LCS)of fuel cells is challenged by significant time delays,model uncertainties,pump and fan coupling,and frequent disturbances,leading to overshoot and control oscillations that degrade temperature regulation performance.To address these challenges,we propose a composite control scheme combining fuzzy logic and a variable-gain generalized supertwisting algorithm(VG-GSTA).Firstly,a one-dimensional(1D)fuzzy logic controler(FLC)for the pump ensures stable coolant flow,while a two-dimensional(2D)FLC for the fan regulates the stack temperature near the reference value.The VG-GSTA is then introduced to eliminate steady-state errors,offering resistance to disturbances and minimizing control oscillations.The equilibrium optimizer is used to fine-tune VG-GSTA parameters.Co-simulation verifies the effectiveness of our method,demonstrating its advantages in terms of disturbance immunity,overshoot suppression,tracking accuracy and response speed. 展开更多
关键词 liquid-cooled fuel cell temperature control generalized supertwisting algorithm fuzzy control equilibrium optimizer
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Research on three-dimensional attack area based on improved backtracking and ALPS-GP algorithms of air-to-air missile
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作者 ZHANG Haodi WANG Yuhui HE Jiale 《Journal of Systems Engineering and Electronics》 2025年第1期292-310,共19页
In the field of calculating the attack area of air-to-air missiles in modern air combat scenarios,the limitations of existing research,including real-time calculation,accuracy efficiency trade-off,and the absence of t... In the field of calculating the attack area of air-to-air missiles in modern air combat scenarios,the limitations of existing research,including real-time calculation,accuracy efficiency trade-off,and the absence of the three-dimensional attack area model,restrict their practical applications.To address these issues,an improved backtracking algorithm is proposed to improve calculation efficiency.A significant reduction in solution time and maintenance of accuracy in the three-dimensional attack area are achieved by using the proposed algorithm.Furthermore,the age-layered population structure genetic programming(ALPS-GP)algorithm is introduced to determine an analytical polynomial model of the three-dimensional attack area,considering real-time requirements.The accuracy of the polynomial model is enhanced through the coefficient correction using an improved gradient descent algorithm.The study reveals a remarkable combination of high accuracy and efficient real-time computation,with a mean error of 91.89 m using the analytical polynomial model of the three-dimensional attack area solved in just 10^(-4)s,thus meeting the requirements of real-time combat scenarios. 展开更多
关键词 air combat three-dimensional attack area improved backtracking algorithm age-layered population structure genetic programming(ALPS-GP) gradient descent algorithm
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Synthesis of thinned linear antenna array using genetic algorithm to lower peak sidelobe level and maintain half-power beamwidth
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作者 STEPANOV Maksim KARASEV Alexey 《Journal of Systems Engineering and Electronics》 2025年第5期1113-1121,共9页
Thinning of antenna arrays has been a popular topic for the last several decades.With increasing computational power,this optimization task acquired a new hue.This paper suggests a genetic algorithm as an instrument f... Thinning of antenna arrays has been a popular topic for the last several decades.With increasing computational power,this optimization task acquired a new hue.This paper suggests a genetic algorithm as an instrument for antenna array thinning.The algorithm with a deliberately chosen fitness function allows synthesizing thinned linear antenna arrays with low peak sidelobe level(SLL)while maintaining the half-power beamwidth(HPBW)of a full linear antenna array.Based on results from existing papers in the field and known approaches to antenna array thinning,a classification of thinning types is introduced.The optimal thinning type for a linear thinned antenna array is determined on the basis of a maximum attainable SLL.The effect of thinning coefficient on main directional pattern characteristics,such as peak SLL and HPBW,is discussed for a number of amplitude distributions. 展开更多
关键词 thinned antenna array genetic algorithm side lobe
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A hybrid genetic algorithm to the program optimization model based on a heterogeneous network
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作者 CHEN Hang DOU Yajie +3 位作者 CHEN Ziyi JIA Qingyang ZHU Chen CHEN Haoxuan 《Journal of Systems Engineering and Electronics》 2025年第4期994-1005,共12页
Project construction and development are an impor-tant part of future army designs.In today’s world,intelligent war-fare and joint operations have become the dominant develop-ments in warfare,so the construction and ... Project construction and development are an impor-tant part of future army designs.In today’s world,intelligent war-fare and joint operations have become the dominant develop-ments in warfare,so the construction and development of the army need top-down,top-level design,and comprehensive plan-ning.The traditional project development model is no longer suf-ficient to meet the army’s complex capability requirements.Projects in various fields need to be developed and coordinated to form a joint force and improve the army’s combat effective-ness.At the same time,when a program consists of large-scale project data,the effectiveness of the traditional,precise mathe-matical planning method is greatly reduced because it is time-consuming,costly,and impractical.To solve above problems,this paper proposes a multi-stage program optimization model based on a heterogeneous network and hybrid genetic algo-rithm and verifies the effectiveness and feasibility of the model and algorithm through an example.The results show that the hybrid algorithm proposed in this paper is better than the exist-ing meta-heuristic algorithm. 展开更多
关键词 program optimization heterogeneous network genetic algorithm portfolio selection.
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Topological optimization of metamaterial absorber based on improved estimation of distribution algorithm
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作者 TAO Shifei LIU Beichen +2 位作者 LIU Sixing WU Fan WANG Hao 《Journal of Systems Engineering and Electronics》 2025年第3期634-641,共8页
An improved estimation of distribution algorithm(IEDA)is proposed in this paper for efficient design of metamaterial absorbers.This algorithm establishes a probability model through the selected dominant groups and sa... An improved estimation of distribution algorithm(IEDA)is proposed in this paper for efficient design of metamaterial absorbers.This algorithm establishes a probability model through the selected dominant groups and samples from the model to obtain the next generation,avoiding the problem of building-blocks destruction caused by crossover and mutation.Neighboring search from artificial bee colony algorithm(ABCA)is introduced to enhance the local optimization ability and improved to raise the speed of convergence.The probability model is modified by boundary correction and loss correction to enhance the robustness of the algorithm.The proposed IEDA is compared with other intelligent algorithms in relevant references.The results show that the proposed IEDA has faster convergence speed and stronger optimization ability,proving the feasibility and effectiveness of the algorithm. 展开更多
关键词 METAMATERIAL topological optimization estimation of distribution algorithm
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Optimization model for performance-based warranty decision of degraded systems based on improved sparrow search algorithm
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作者 DONG Enzhi CHENG Zhonghua +3 位作者 LIU Zichang ZHU Xi WANG Rongcai BAI Yongsheng 《Journal of Systems Engineering and Electronics》 2025年第5期1259-1280,共22页
Performance-based warranties(PBWs)are widely used in industry and manufacturing.Given that PBW can impose financial burdens on manufacturers,rational maintenance decisions are essential for expanding profit margins.Th... Performance-based warranties(PBWs)are widely used in industry and manufacturing.Given that PBW can impose financial burdens on manufacturers,rational maintenance decisions are essential for expanding profit margins.This paper proposes an optimization model for PBW decisions for systems affected by Gamma degradation processes,incorporating periodic inspection.A system performance degradation model is established.Preventive maintenance probability and corrective renewal probability models are developed to calculate expected warranty costs and system availability.A benefits function,which includes incentives,is constructed to optimize the initial and subsequent inspection intervals and preventive maintenance thresholds,thereby maximizing warranty profit.An improved sparrow search algorithm is developed to optimize the model,with a case study on large steam turbine rotor shafts.The results suggest the optimal PBW strategy involves an initial inspection interval of approximately 20 months,with subsequent intervals of about four months,and a preventive maintenance threshold of approximately 37.39 mm wear.When compared to common cost-minimization-based condition maintenance strategies and PBW strategies that do not differentiate between initial and subsequent inspection intervals,the proposed PBW strategy increases the manufacturer’s profit by 1%and 18%,respectively.Sensitivity analyses provide managerial recommendations for PBW implementation.The PBW strategy proposed in this study significantly increases manufacturers’profits by optimizing inspection intervals and preventive maintenance thresholds,and manufacturers should focus on technological improvement in preventive maintenance and cost control to further enhance earnings. 展开更多
关键词 performance-based warranty gamma process periodic inspection intelligent optimization algorithm
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Bayesian-based ant colony optimization algorithm for edge detection
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作者 YU Yongbin ZHONG Yuanjingyang +6 位作者 FENG Xiao WANG Xiangxiang FAVOUR Ekong ZHOU Chen CHENG Man WANG Hao WANG Jingya 《Journal of Systems Engineering and Electronics》 2025年第4期892-902,共11页
Ant colony optimization(ACO)is a random search algorithm based on probability calculation.However,the uninformed search strategy has a slow convergence speed.The Bayesian algorithm uses the historical information of t... Ant colony optimization(ACO)is a random search algorithm based on probability calculation.However,the uninformed search strategy has a slow convergence speed.The Bayesian algorithm uses the historical information of the searched point to determine the next search point during the search process,reducing the uncertainty in the random search process.Due to the ability of the Bayesian algorithm to reduce uncertainty,a Bayesian ACO algorithm is proposed in this paper to increase the convergence speed of the conventional ACO algorithm for image edge detection.In addition,this paper has the following two innovations on the basis of the classical algorithm,one of which is to add random perturbations after completing the pheromone update.The second is the use of adaptive pheromone heuristics.Experimental results illustrate that the proposed Bayesian ACO algorithm has faster convergence and higher precision and recall than the traditional ant colony algorithm,due to the improvement of the pheromone utilization rate.Moreover,Bayesian ACO algorithm outperforms the other comparative methods in edge detection task. 展开更多
关键词 ant colony optimization(ACO) Bayesian algorithm edge detection transfer function.
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An improved genetic algorithm for causal discovery
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作者 MAO Tengjiao BU Xianjin +2 位作者 CAI Chunxiao LU Yue DU Jing 《Journal of Systems Engineering and Electronics》 2025年第3期768-777,共10页
The learning algorithms of causal discovery mainly include score-based methods and genetic algorithms(GA).The score-based algorithms are prone to searching space explosion.Classical GA is slow to converge,and prone to... The learning algorithms of causal discovery mainly include score-based methods and genetic algorithms(GA).The score-based algorithms are prone to searching space explosion.Classical GA is slow to converge,and prone to falling into local optima.To address these issues,an improved GA with domain knowledge(IGADK)is proposed.Firstly,domain knowledge is incorporated into the learning process of causality to construct a new fitness function.Secondly,a dynamical mutation operator is introduced in the algorithm to accelerate the convergence rate.Finally,an experiment is conducted on simulation data,which compares the classical GA with IGADK with domain knowledge of varying accuracy.The IGADK can greatly reduce the number of iterations,populations,and samples required for learning,which illustrates the efficiency and effectiveness of the proposed algorithm. 展开更多
关键词 genetic algorithm(GA) causal discovery convergence rate fitness function mutation operator
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Functional cartography of heterogeneous combat networks using operational chain-based label propagation algorithm
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作者 CHEN Kebin JIANG Xuping +2 位作者 ZENG Guangjun YANG Wenjing ZHENG Xue 《Journal of Systems Engineering and Electronics》 2025年第5期1202-1215,共14页
To extract and display the significant information of combat systems,this paper introduces the methodology of functional cartography into combat networks and proposes an integrated framework named“functional cartogra... To extract and display the significant information of combat systems,this paper introduces the methodology of functional cartography into combat networks and proposes an integrated framework named“functional cartography of heterogeneous combat networks based on the operational chain”(FCBOC).In this framework,a functional module detection algorithm named operational chain-based label propagation algorithm(OCLPA),which considers the cooperation and interactions among combat entities and can thus naturally tackle network heterogeneity,is proposed to identify the functional modules of the network.Then,the nodes and their modules are classified into different roles according to their properties.A case study shows that FCBOC can provide a simplified description of disorderly information of combat networks and enable us to identify their functional and structural network characteristics.The results provide useful information to help commanders make precise and accurate decisions regarding the protection,disintegration or optimization of combat networks.Three algorithms are also compared with OCLPA to show that FCBOC can most effectively find functional modules with practical meaning. 展开更多
关键词 functional cartography heterogeneous combat network functional module label propagation algorithm operational chain
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A tracking algorithm based on adaptive Kalman filter with carrier-to-noise ratio estimation under solar radio bursts interference
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作者 ZHU Xuefen LI Ang +2 位作者 LUO Yimei LIN Mengying TU Gangyi 《Journal of Systems Engineering and Electronics》 2025年第4期880-891,共12页
Solar radio burst(SRB)is one of the main natural interference sources of Global Positioning System(GPS)signals and can reduce the signal-to-noise ratio(SNR),directly affecting the tracking performance of GPS receivers... Solar radio burst(SRB)is one of the main natural interference sources of Global Positioning System(GPS)signals and can reduce the signal-to-noise ratio(SNR),directly affecting the tracking performance of GPS receivers.In this paper,a tracking algorithm based on the adaptive Kalman filter(AKF)with carrier-to-noise ratio estimation is proposed and compared with the conventional second-order phase-locked loop tracking algo-rithms and the improved Sage-Husa adaptive Kalman filter(SHAKF)algorithm.It is discovered that when the SRBs occur,the improved SHAKF and the AKF with carrier-to-noise ratio estimation enable stable tracking to loop signals.The conven-tional second-order phase-locked loop tracking algorithms fail to track the receiver signal.The standard deviation of the carrier phase error of the AKF with carrier-to-noise ratio estimation out-performs 50.51%of the improved SHAKF algorithm,showing less fluctuation and better stability.The proposed algorithm is proven to show more excellent adaptability in the severe envi-ronment caused by the SRB occurrence and has better tracking performance. 展开更多
关键词 solar radio burst(SRB) global positioning system(GPS) adaptive Kalman filter(AKF) tracking algorithm.
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维生素D水平与反复呼吸道感染患儿免疫障碍的相关性 被引量:2
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作者 朱瑛 南楠 +2 位作者 李婷婷 魏丽琼 黄蕾 《中国免疫学杂志》 北大核心 2025年第3期668-674,679,共8页
目的:调查甘肃省儿童维生素D水平特征,分析维生素D水平与反复呼吸道感染(RRTIs)患儿免疫障碍的相关性。方法:回顾性选取2020年1月至2021年12月期间于甘肃省6个市州妇幼保健院及三级综合医院以上儿科行维生素D检测的9790例0~6岁儿童,分... 目的:调查甘肃省儿童维生素D水平特征,分析维生素D水平与反复呼吸道感染(RRTIs)患儿免疫障碍的相关性。方法:回顾性选取2020年1月至2021年12月期间于甘肃省6个市州妇幼保健院及三级综合医院以上儿科行维生素D检测的9790例0~6岁儿童,分析其中5000例儿童维生素D特征,以5000例中出现RRTIs的90例患儿作为研究组,以80例健康儿童作为对照组。对比两组维生素D水平与免疫功能指标(IgA、IgG、IgM、补体C3、补体C4)的相关性,分析维生素D对儿童RRTIs的诊断价值。结果:分析甘肃省5000例儿童维生素D资料发现,维生素D缺乏率、不足率、充足率分别为11.58%、41.38%、47.04%,未发现维生素D过量和中毒者。儿童维生素D水平受年龄和季节的影响,3~4岁儿童维生素D缺乏较严重,冬季儿童维生素D水平最低,且维生素D水平与儿童生长发育、罹患疾病有关。研究组25(OH)D水平、免疫功能指标均低于对照组(P<0.05)。25(OH)D水平与RRTIs患儿年龄、过敏史、被动烟草暴露、易感季节有关(P<0.05)。维生素D充足患儿免疫功能指标高于维生素D不足、缺乏患儿(P<0.05)。RRTIs患儿维生素D水平与免疫功能呈正相关(P<0.05)。低出生体重、早产、偏食、每日果蔬量、户外活动时间、钙、铁、锌、25(OH)D、IgA、IgG、IgM、补体C3、补体C4均是儿童RRTIs的独立危险因素(P<0.05),维生素D对儿童RRTIs的诊断价值较高(P<0.05)。结论:甘肃省儿童维生素D水平与年龄、季节相关,在儿童RRTIs中,维生素D水平降低与患儿机体免疫障碍有关,可用于RRTIs的诊断。 展开更多
关键词 维生素d 25-羟基维生素d 儿童反复呼吸道感染 免疫球蛋白 补体
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维生素D治疗全面性发育迟缓患儿的临床疗效研究 被引量:3
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作者 牛国辉 谢加阳 +6 位作者 朱登纳 崔博 赵会玲 王明梅 冯欢欢 张萌萌 李停停 《中国全科医学》 CAS 北大核心 2025年第3期346-351,共6页
背景 除了某些有明确病因的代谢性疾病导致的全面性发育迟缓(GDD),康复治疗是GDD的主要治疗方式;维生素D通过影响神经营养因子在调节神经细胞的发育和分化方面发挥着重要的神经保护作用;但目前关于补充维生素D对GDD患儿临床疗效的研究... 背景 除了某些有明确病因的代谢性疾病导致的全面性发育迟缓(GDD),康复治疗是GDD的主要治疗方式;维生素D通过影响神经营养因子在调节神经细胞的发育和分化方面发挥着重要的神经保护作用;但目前关于补充维生素D对GDD患儿临床疗效的研究开展较少。目的 探讨补充不同剂量的维生素D对GDD患儿康复治疗的临床效果。方法 于2020年9月—2022年6月选取在郑州大学第三附属医院康复医学科首次住院就诊的120例GDD患儿为研究对象,采用随机区组化的方法将其分为常规组(38例)、400 U组(37例)和1 200 U组(35例)。常规组仅进行常规康复治疗;400 U组在常规康复治疗的基础上给予口服400 U/d维生素D;1 200 U组在常规康复训练的基础上给予口服1 200 U/d维生素D。收集3组患儿的性别、就诊年龄等基本资料;于入院时(治疗前)及第3个疗程末(治疗后)行血清25羟维生素D[25(OH)D]水平检测和Gesell发育量表评估[评估适应能力、大运动能力、精细运动能力、语言能力和社交能力5个能区的发育商(DQ)];记录发生在患儿住院期间不良事件的次数,并对上述资料进行分析比较。结果 3组患儿性别、居住地、出生季节、分娩方式、就诊年龄、出生体质量、出生胎龄、主要就诊原因比较,差异均无统计学意义(P>0.05)。治疗前,3组患儿25(OH)D水平、Gesell量表各能区DQ值比较,差异均无统计学意义(P>0.05);治疗后,1 200 U组患儿血25(OH)D水平、Gesell量表大运动能力、精细运动能力、语言能力DQ值高于常规组(P<0.05)。第1、2疗程期间,3组患儿不良事件发生率比较,差异无统计学意义(P>0.05);第3疗程期间,1 200 U组患儿不良事件发生率低于常规组及400 U组(P<0.05)。结论 补充1 200 U维生素D对GDD患儿的康复疗效有益,且能减少康复期间不良事件的发生率。 展开更多
关键词 儿童发育障碍 广泛性 全面性发育迟缓 维生素d Gesell量表 不良事件 康复治疗 神经保护
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融合改进D^(*)与RRT算法的单AGV路径规划算法
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作者 赵学健 叶昊 +2 位作者 江宇航 袁凯 孙知信 《小型微型计算机系统》 北大核心 2025年第8期1847-1860,共14页
本研究针对单自动导引车(AGV)的路径规划问题,深入剖析了现有多阶段路径规划方法的局限性,并提出了一种融合改进D^(*)与快速探索随机树(RRT)算法的路径规划算法.该算法结合了改进D^(*)算法的高效性与RRT算法的灵活性,通过动态避障策略... 本研究针对单自动导引车(AGV)的路径规划问题,深入剖析了现有多阶段路径规划方法的局限性,并提出了一种融合改进D^(*)与快速探索随机树(RRT)算法的路径规划算法.该算法结合了改进D^(*)算法的高效性与RRT算法的灵活性,通过动态避障策略和目标约束优化,显著提升了路径规划性能.引入自适应视野、步长、威胁因子及目标点采样率等参数,以适应多变环境需求.利用Rich_Moore元胞自动机方法扩展可行区域并确定最短路径,并通过高阶贝塞尔曲线平滑路径,减少转向,提高路径平滑度.实验结果证明,该算法在精度和效率上均优于传统方法,对提升AGV作业实时性和准确性,推动自动化物流系统发展具有显著意义. 展开更多
关键词 AGV 随机树算法 d^(*)算法 路径规划 智能物流
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1株羊源D型产气荚膜梭菌的分离鉴定及耐药性分析 被引量:3
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作者 李娜 刘重阳 +4 位作者 张靖靖 玛丽雅其其格 珠娜 陆斌 海鹰 《中国畜牧兽医》 北大核心 2025年第3期1352-1359,共8页
【目的】D型产气荚膜梭菌是一种革兰阳性厌氧菌,可引起山羊、绵羊和牛等动物发生肠毒血症,对反刍动物的健康造成巨大的影响。本研究旨在了解内蒙古乌审旗地区D型产气荚膜梭菌耐药情况,为该地区由D型产气荚膜梭菌引起的疾病的治疗提供科... 【目的】D型产气荚膜梭菌是一种革兰阳性厌氧菌,可引起山羊、绵羊和牛等动物发生肠毒血症,对反刍动物的健康造成巨大的影响。本研究旨在了解内蒙古乌审旗地区D型产气荚膜梭菌耐药情况,为该地区由D型产气荚膜梭菌引起的疾病的治疗提供科学依据。【方法】通过培养特性及革兰染色镜检对分离菌进行初步鉴定,通过16S rRNA基因序列比对和毒素基因PCR扩增对可疑菌株进一步鉴定,并采用K-B纸片法进行药敏试验,PCR检测分离菌耐药基因。【结果】分离菌在TSC培养基中长出黑色的圆形菌落,革兰染色镜检可见菌体粗短,成单个或双个排列的革兰阳性直杆菌,形态学及镜检结果符合产气荚膜梭菌特点。16S rRNA基因序列比对结果显示,分离菌与NCBI数据库中已公布的产气荚膜梭菌16S rRNA基因序列相似性均>99%,鉴定该菌株为产气荚膜梭菌。毒素基因PCR检测扩增出cpa和etx基因,表明该菌株为D型产气荚膜梭菌。药敏试验结果显示,分离菌对头孢曲松、头孢呋新、庆大霉素等16种抗菌药耐药。耐药基因检测结果显示,分离菌检出bla CTX-M、bla SHV、qnrA和aac(6′)-Ⅰb-cr 4种耐药基因,未检出bla TEM和qnrS 2种耐药基因。【结论】本试验成功从绵羊体内分离出1株D型产气荚膜梭菌,该菌株存在多重耐药,该研究结果为D型产气荚膜梭菌感染绵羊的诊断、流行病学调查和治疗提供了参考依据。 展开更多
关键词 绵羊 d型产气荚膜梭菌 分离鉴定 耐药性
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超高强度A柱加强板热冲压质量自适应MOEA/D优化
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作者 裴宝浩 肖振 +1 位作者 周娟 于蓬 《机械设计与制造》 北大核心 2025年第9期255-259,265,共6页
为了提高超高强度A柱加强板热冲压成形质量,提出了基于自适应MOEA/D算法的冲压参数多目标优化方法。使用数值模拟法分析了超高强度A柱加强板热冲压质量问题,并针对最大减薄率和最大增厚率建立了多目标优化模型。在仿真数据基础上,使用Kr... 为了提高超高强度A柱加强板热冲压成形质量,提出了基于自适应MOEA/D算法的冲压参数多目标优化方法。使用数值模拟法分析了超高强度A柱加强板热冲压质量问题,并针对最大减薄率和最大增厚率建立了多目标优化模型。在仿真数据基础上,使用Kriging模型拟合了质量参数与工艺参数间模型。将优化变量编码为基因,从而将冲压优化问题转化为算法寻优问题。为了提高MOEA/D算法的优化能力,在算法中引入了自适应差异性惩罚方案,进而提出了基于自适应MOEA/D算法的优化方法。经生产优化,优化后产品的金相组织实现了预期变化,最大减薄率均值由17.1%减小为14.5%,最大增厚率均值由18.1%减小为15.7%,实验结果证明了自适应MOEA/D优化算法的优越性。 展开更多
关键词 超高强度 A柱加强板 冲压优化 MOEA/d算法 自适应差异性惩罚方案
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计算机模拟手术结合3D打印技术在复杂骨折手术中的应用进展 被引量:5
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作者 杨立宇 郭文娟 +2 位作者 叶飞 张一奇 巴根 《中国医科大学学报》 北大核心 2025年第2期167-170,177,共5页
以计算机辅助设计为基础的3D打印技术能够快速制作三维立体模型,清晰显示骨折部位的解剖结构、类型和破裂程度,为了解骨折情况提供全方位的视觉化手段。该技术还能帮助医生设计个性化的植入物,选择定制的手术导向板和固定螺丝。手术医... 以计算机辅助设计为基础的3D打印技术能够快速制作三维立体模型,清晰显示骨折部位的解剖结构、类型和破裂程度,为了解骨折情况提供全方位的视觉化手段。该技术还能帮助医生设计个性化的植入物,选择定制的手术导向板和固定螺丝。手术医生通过术前模拟操作,对手术方案进行优化,提高手术的准确性和效果。本文总结了计算机模拟手术结合3D打印技术在多种骨科手术中的应用情况,并广泛阐述了3D打印技术在临床骨科领域的巨大应用潜力。 展开更多
关键词 计算机辅助设计 3d打印 复杂骨折
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对美国内分泌学会2024年版维生素D指南重大修订的思考 被引量:1
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作者 谢忠建 《中华骨质疏松和骨矿盐疾病杂志》 北大核心 2025年第2期135-140,共6页
自从美国内分泌学会2011年发布首版维生素D指南以来,随着多项大型随机对照研究(randomized clinical trial,RCT)的结果发表,美国内分泌学会于2024年对维生素D指南进行了修订,本文介绍了新版指南的修订背景和具体修订内容,并探讨该指南... 自从美国内分泌学会2011年发布首版维生素D指南以来,随着多项大型随机对照研究(randomized clinical trial,RCT)的结果发表,美国内分泌学会于2024年对维生素D指南进行了修订,本文介绍了新版指南的修订背景和具体修订内容,并探讨该指南的推荐是否适合中国人群。本次修订幅度较大,首先废除了根据25-羟维生素D[25 hydroxyvitamin D,25(OH)D]水平所定义的维生素D“缺乏”和“不足”的分类,原因是临床研究尚未明确与特定临床结果关联的25(OH)D水平的阈值。并且,对于一般健康人群,不建议常规检测血清25(OH)D水平。对于18~74岁的健康成年人,摄入维生素D的膳食参考摄入量(600~800 IU/d)即可满足需要。而其他健康人群,如儿童、青少年、老年人、孕妇和糖尿病前期人群,则建议更高的“经验性补充”剂量。需明确的是,新版指南针对的是健康人群,而非患病人群。对于1~18岁的儿童和青少年,“经验性补充维生素D”有助于预防营养性佝偻病,并可能降低呼吸道感染风险;对于75岁及以上的老年人群,“经验性补充维生素D”有可能降低死亡风险;对于妊娠女性,“经验性补充维生素D”可能降低先兆子痫、早产和小于胎龄儿的风险及宫内死亡率;对于糖尿病前期人群,“经验性补充维生素D”可能减低从糖尿病前期进展为糖尿病的风险。鉴于各临床研究中的维生素D补充剂量差异较大,目前尚不明确最佳补充剂量,指南仅列出了临床研究中使用的剂量范围,供“经验性补充”参考。此外,指南建议50岁以上、跌倒风险较高的人群小剂量补充,而不建议过大剂量补充。 展开更多
关键词 维生素d 美国内分泌学会 指南
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