The design of collaboration decision of C2 system is one of the puzzles which dicision science studies in complex system. To solve the contravention between the theory of collaboration decision design and development ...The design of collaboration decision of C2 system is one of the puzzles which dicision science studies in complex system. To solve the contravention between the theory of collaboration decision design and development requirement in distributed C2 system,three-stage design approach is proposed to research coherence and optimization by which decision-maker carries out decision regulations. First,getting information and decision process are described; decision indexes and regulation models of collaboration are established. And then,a test circumstance is designed and established for measuring various decision-maker’s capabilities of carrying out decision regulation by simulation and getting their load capability parameters. Finally,the obtained parameters from the experiment are disposed and substituted into the original models for proving the coherence of decision regulations. As a result,it is feasible for three-stage approach to design collaboration decision,and decision regulations can satisfy various decision-maker requirements.展开更多
指挥控制(command and control,C2)系统作为军事体系的“神经中枢”,其形态与效能直接决定战争形态与胜负走向。随着全域作战、智能化作战等新型作战样式的演进,传统基于编制预设的C2体系面临跨域协同不足、动态适应能力薄弱等瓶颈。“...指挥控制(command and control,C2)系统作为军事体系的“神经中枢”,其形态与效能直接决定战争形态与胜负走向。随着全域作战、智能化作战等新型作战样式的演进,传统基于编制预设的C2体系面临跨域协同不足、动态适应能力薄弱等瓶颈。“软件定义C2”通过软件重构硬件逻辑。展开更多
当今空天信息卫星互联技术蓬勃发展,通过卫星遥感、导航、通信、计算机科学、信息工程等技术获取、处理和利用空天信息资源,已经被广泛用于军事、民用、商业领域。空天信息资源可以提高指挥与控制(com⁃mand and control,C2)系统对陆、...当今空天信息卫星互联技术蓬勃发展,通过卫星遥感、导航、通信、计算机科学、信息工程等技术获取、处理和利用空天信息资源,已经被广泛用于军事、民用、商业领域。空天信息资源可以提高指挥与控制(com⁃mand and control,C2)系统对陆、海、空、天、电、网等全域态势的感知和认知水平,提升指挥协同与决策效率;也可以为低空经济、应急指挥调度、数字孪生城市、车路协同网络等提供地理信息、气象信息、环境信息等丰富的数据支持。特别是人工智能、大模型、机器学习等智能技术融入空天信息资源的不断发展应用,也为现代C2带来了新挑战、新机遇。展开更多
目的研究胰高血糖素样肽素-1(glucogon like pep tide-1,GLP-1)对晚期糖基化终产物(advanced glycation end products,AGEs)诱导H9C2心肌细胞凋亡的保护作用机制。方法体外培养H9C2细胞,实验分为4组:正常对照组、100 mg·L^(-1)AGE...目的研究胰高血糖素样肽素-1(glucogon like pep tide-1,GLP-1)对晚期糖基化终产物(advanced glycation end products,AGEs)诱导H9C2心肌细胞凋亡的保护作用机制。方法体外培养H9C2细胞,实验分为4组:正常对照组、100 mg·L^(-1)AGEs试验组、AGEs(100 mg·L^(-1))+GLP-1(10 nmol·L^(-1))组、AGEs(100 mg·L^(-1))+NAC(5 mmol·L^(-1))组,处理24 h。通过CCK-8比色法检测细胞存活率,相差显微镜观察细胞形态,双氯荧光素(DCFH-DA)染色荧光显微镜摄片观察细胞内活性氧(ROS)水平;RT-PCR法测定Bax、Bcl-2 mRNA基因的表达;运用Hoechst 33258检测试剂盒及流式细胞术检测心肌细胞的凋亡率,Western blot检测凋亡相关蛋白Bax、Bcl-2的表达量。结果与正常组相比,100 mg·L^(-1)AGEs组降低H9C2细胞生存率,活性氧(ROS)生成量增加;与AGEs组相比,AGEs+GLP-1组细胞生成率提高,活性氧(ROS)生成量减少。与正常组相比,AGEs组促凋亡蛋白Bax表达增加,抑制凋亡蛋白Bcl-2减少,细胞凋亡率升高;AGEs+GLP-1组较AGEs组下调促凋亡蛋白Bax,上调凋亡抑制蛋白Bcl-2,细胞凋亡率减少。结论 GLP-1对AGEs诱导的心肌细胞凋亡具有保护作用,其保护机制与减少活性氧(ROS)有关。展开更多
基金the National Nature Science Foundation of China (70671105)
文摘The design of collaboration decision of C2 system is one of the puzzles which dicision science studies in complex system. To solve the contravention between the theory of collaboration decision design and development requirement in distributed C2 system,three-stage design approach is proposed to research coherence and optimization by which decision-maker carries out decision regulations. First,getting information and decision process are described; decision indexes and regulation models of collaboration are established. And then,a test circumstance is designed and established for measuring various decision-maker’s capabilities of carrying out decision regulation by simulation and getting their load capability parameters. Finally,the obtained parameters from the experiment are disposed and substituted into the original models for proving the coherence of decision regulations. As a result,it is feasible for three-stage approach to design collaboration decision,and decision regulations can satisfy various decision-maker requirements.
文摘当今空天信息卫星互联技术蓬勃发展,通过卫星遥感、导航、通信、计算机科学、信息工程等技术获取、处理和利用空天信息资源,已经被广泛用于军事、民用、商业领域。空天信息资源可以提高指挥与控制(com⁃mand and control,C2)系统对陆、海、空、天、电、网等全域态势的感知和认知水平,提升指挥协同与决策效率;也可以为低空经济、应急指挥调度、数字孪生城市、车路协同网络等提供地理信息、气象信息、环境信息等丰富的数据支持。特别是人工智能、大模型、机器学习等智能技术融入空天信息资源的不断发展应用,也为现代C2带来了新挑战、新机遇。
