Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures. To understand the functions of RNAs, some st...Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures. To understand the functions of RNAs, some structure prediction models have been developed in recent years. In this review, the progress in computational models for RNA structure prediction is introduced and the distinguishing features of many outstanding algorithms are discussed, emphasizing three- dimensional （3D） structure prediction. A promising coarse-grained model for predicting RNA 3D structure, stability and salt effect is also introduced briefly. Finally, we discuss the major challenges in the RNA 3D structure modeling.展开更多
The dynamic phase transition properties for ferroelectric nanotube under a spin-1/2 transverse Ising model are studied under the effective field theory(EFT)with correlations.The temperature effects on the pseudo-spin ...The dynamic phase transition properties for ferroelectric nanotube under a spin-1/2 transverse Ising model are studied under the effective field theory(EFT)with correlations.The temperature effects on the pseudo-spin systems are unveiled in three-dimensional(3-D)and two-dimensional(2-D)phase diagrams.Moreover,the dynamic behaviors of exchange interactions on the 3-D and 2-D phase transitions under high temperature are exhibited.The results present that it is hard to obtain pure ferroelectric phase under high temperature;that is,the vibration of orderly pseudo-spins cannot be eliminated completely.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.11074191,11175132,and 11374234)the National Basic Research Programof China(Grant No.2011CB933600)the Program for New Century Excellent Talents of China(Grant No.NCET 08-0408)
文摘Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures. To understand the functions of RNAs, some structure prediction models have been developed in recent years. In this review, the progress in computational models for RNA structure prediction is introduced and the distinguishing features of many outstanding algorithms are discussed, emphasizing three- dimensional （3D） structure prediction. A promising coarse-grained model for predicting RNA 3D structure, stability and salt effect is also introduced briefly. Finally, we discuss the major challenges in the RNA 3D structure modeling.
基金Project supported by the National Key R&D Program of China(Grant No.2017YFE0120500)the National Natural Science Foundation of China(Grant No.51972129)+3 种基金the South Xinjiang Innovation and Development Program of Key Industries of Xinjiang Production and Construction Corps(Grant No.2020DB002)the Fundamental Research Funds for the Central Universities,China(Grant Nos.HUST 2018KFYYXJJ051 and 2019KFYXMBZ076)Shenzhen Fundamental Research Fund(Grant No.JCYJ20190813172609404)the Hubei“Chu-Tian Young Scholar”Program。
文摘The dynamic phase transition properties for ferroelectric nanotube under a spin-1/2 transverse Ising model are studied under the effective field theory(EFT)with correlations.The temperature effects on the pseudo-spin systems are unveiled in three-dimensional(3-D)and two-dimensional(2-D)phase diagrams.Moreover,the dynamic behaviors of exchange interactions on the 3-D and 2-D phase transitions under high temperature are exhibited.The results present that it is hard to obtain pure ferroelectric phase under high temperature;that is,the vibration of orderly pseudo-spins cannot be eliminated completely.
