This paper reports that in the presence of cetyltrimethyl ammonium bromide as phase transfer catalyst,D-glucosamine hydrochloride reacts with 2,4-dinitrophenol to synthesize 1-O-(2’,4’-dinitrophenyl)-2-acetamido-β-...This paper reports that in the presence of cetyltrimethyl ammonium bromide as phase transfer catalyst,D-glucosamine hydrochloride reacts with 2,4-dinitrophenol to synthesize 1-O-(2’,4’-dinitrophenyl)-2-acetamido-β-D-glucoside.Chemical structure of the new compound was confirmed by elemental analysis,IR and UV.展开更多
A series of protected and deprotected 2 - deoxy -2 - aromatic acyl -β- D - glucopyranoses are prepared. Six of them are confirmed by IR,1H NMR,13C NMR and elementary analyses. The preliminary antibacterial activities...A series of protected and deprotected 2 - deoxy -2 - aromatic acyl -β- D - glucopyranoses are prepared. Six of them are confirmed by IR,1H NMR,13C NMR and elementary analyses. The preliminary antibacterial activities against staphylococcus albus and escherichia coli are studied. The result show that all the deprotected products has a good antibacterial ability to the two bacterias,while the products protected by acetyl show no activity.展开更多
Starting from \%D\%\|galactose, per\|\%O\|\%acetylated (\%S\%)\|TBMB carboxylic acid derivant of methyl\|4\|amino\|4\|deoxy\|\%D\%\|glucopyranoside was prepared. The mechanism of the possible side reactions of the cat...Starting from \%D\%\|galactose, per\|\%O\|\%acetylated (\%S\%)\|TBMB carboxylic acid derivant of methyl\|4\|amino\|4\|deoxy\|\%D\%\|glucopyranoside was prepared. The mechanism of the possible side reactions of the catalytic reduction from different types of azide sugar to the corresponding amino sugar was discussed. 1\|\%O\%\|Me\|protection was selected for preventing the intramolecular dehydration of the 4\|amino sugar, which was a key intermediate product in this synthetic process. The product was characterized by HRMS and \{\{\}\+1H NMR\} spectroscopy and will be used as a molecular model to develop a new identification method of the \%D, L\|\%configurations of amino sugar.展开更多
文摘This paper reports that in the presence of cetyltrimethyl ammonium bromide as phase transfer catalyst,D-glucosamine hydrochloride reacts with 2,4-dinitrophenol to synthesize 1-O-(2’,4’-dinitrophenyl)-2-acetamido-β-D-glucoside.Chemical structure of the new compound was confirmed by elemental analysis,IR and UV.
文摘A series of protected and deprotected 2 - deoxy -2 - aromatic acyl -β- D - glucopyranoses are prepared. Six of them are confirmed by IR,1H NMR,13C NMR and elementary analyses. The preliminary antibacterial activities against staphylococcus albus and escherichia coli are studied. The result show that all the deprotected products has a good antibacterial ability to the two bacterias,while the products protected by acetyl show no activity.
文摘Starting from \%D\%\|galactose, per\|\%O\|\%acetylated (\%S\%)\|TBMB carboxylic acid derivant of methyl\|4\|amino\|4\|deoxy\|\%D\%\|glucopyranoside was prepared. The mechanism of the possible side reactions of the catalytic reduction from different types of azide sugar to the corresponding amino sugar was discussed. 1\|\%O\%\|Me\|protection was selected for preventing the intramolecular dehydration of the 4\|amino sugar, which was a key intermediate product in this synthetic process. The product was characterized by HRMS and \{\{\}\+1H NMR\} spectroscopy and will be used as a molecular model to develop a new identification method of the \%D, L\|\%configurations of amino sugar.
