Twelve new Schiff bases of thiadiazole have been synthesized for the first time. Their physical constants, UV, IR, 1H NMR and elementary analysis were originally characterized, biological activity were originally stud...Twelve new Schiff bases of thiadiazole have been synthesized for the first time. Their physical constants, UV, IR, 1H NMR and elementary analysis were originally characterized, biological activity were originally studied. It is found from the results of biological activity tests that some compounds have a remarkable activity on plant growth hormone. Compounds Ⅲa and Ⅲk have a good activity on cytokinin, compounds Ⅲe and Ⅲj and Ⅲl have an excellent activity on auxin.展开更多
A series of 1 substituted phenoxyacetyl 4 aroyl thiosemicarbazides were synthe sized by reaction of aroylisothiocyanate with (substituted)phenoxyacetic acid hydrazides under solid liquid phase transfer catalysis condi...A series of 1 substituted phenoxyacetyl 4 aroyl thiosemicarbazides were synthe sized by reaction of aroylisothiocyanate with (substituted)phenoxyacetic acid hydrazides under solid liquid phase transfer catalysis condition. The preliminary bioassay results showed that some of the compounds have good antibiotic activity and plant growth regulation activity. The compounds were characterized by elemental analysis, IR and 1H NMR.展开更多
Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structure...Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structures of the title compounds were confirmed by IR, 1H NMR and elemental analysis. The room temperature biological activity tests showed that some target compounds have a good activity as plant growth regulator, the best of them appeared compounds Ⅱ b and Ⅱ c(for auxin).展开更多
Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H...Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H NMR, UV and MS. Some of these compounds showed antitumor activities in vitro.展开更多
In this article, generalized torsion angles of derivatives of 1 [(2 hydroxyethoxy)methyl] 6 (phenylthio)thymine(HEPT) were calculated, which include abundant three dimensional information of molecules. Molecular simil...In this article, generalized torsion angles of derivatives of 1 [(2 hydroxyethoxy)methyl] 6 (phenylthio)thymine(HEPT) were calculated, which include abundant three dimensional information of molecules. Molecular similarity matrix was built based on the calculated generalized torsion angles. These similarities were taken as the new variables, and the new variables were selected by using Leaps and Bounds regression analysis. Multiple regression analysis and neural networks were performed, and the satisfactory results were achieved by using the neural networks.展开更多
Thirty acylthiosemicarbazide derivatives(Ⅰ) were synthesized by addition reaction of 5 aryl 2 furoyl isothiocyanate(Ⅲ) with aroylhydrazines(Ⅱ). Their compositions and structures were confirmed by elemental analysis...Thirty acylthiosemicarbazide derivatives(Ⅰ) were synthesized by addition reaction of 5 aryl 2 furoyl isothiocyanate(Ⅲ) with aroylhydrazines(Ⅱ). Their compositions and structures were confirmed by elemental analysis, IR and 1H NMR spectrometry measurements. The plant growth effects of these compounds on rice and cucumber have been tested preliminarily.展开更多
文摘Twelve new Schiff bases of thiadiazole have been synthesized for the first time. Their physical constants, UV, IR, 1H NMR and elementary analysis were originally characterized, biological activity were originally studied. It is found from the results of biological activity tests that some compounds have a remarkable activity on plant growth hormone. Compounds Ⅲa and Ⅲk have a good activity on cytokinin, compounds Ⅲe and Ⅲj and Ⅲl have an excellent activity on auxin.
文摘A series of 1 substituted phenoxyacetyl 4 aroyl thiosemicarbazides were synthe sized by reaction of aroylisothiocyanate with (substituted)phenoxyacetic acid hydrazides under solid liquid phase transfer catalysis condition. The preliminary bioassay results showed that some of the compounds have good antibiotic activity and plant growth regulation activity. The compounds were characterized by elemental analysis, IR and 1H NMR.
文摘Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structures of the title compounds were confirmed by IR, 1H NMR and elemental analysis. The room temperature biological activity tests showed that some target compounds have a good activity as plant growth regulator, the best of them appeared compounds Ⅱ b and Ⅱ c(for auxin).
文摘Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H NMR, UV and MS. Some of these compounds showed antitumor activities in vitro.
文摘In this article, generalized torsion angles of derivatives of 1 [(2 hydroxyethoxy)methyl] 6 (phenylthio)thymine(HEPT) were calculated, which include abundant three dimensional information of molecules. Molecular similarity matrix was built based on the calculated generalized torsion angles. These similarities were taken as the new variables, and the new variables were selected by using Leaps and Bounds regression analysis. Multiple regression analysis and neural networks were performed, and the satisfactory results were achieved by using the neural networks.
文摘Thirty acylthiosemicarbazide derivatives(Ⅰ) were synthesized by addition reaction of 5 aryl 2 furoyl isothiocyanate(Ⅲ) with aroylhydrazines(Ⅱ). Their compositions and structures were confirmed by elemental analysis, IR and 1H NMR spectrometry measurements. The plant growth effects of these compounds on rice and cucumber have been tested preliminarily.
