目的:通过文献荟萃分析评价利妥昔单抗治疗中重度甲状腺相关眼病的疗效。方法:检索中国知网(CNKI)、万方、维普、中国生物医学、PubMed、Web of Science、OVID、Corhone Library、ClinicalTrial.gov等数据库从建库至2019-12-31发表的关...目的:通过文献荟萃分析评价利妥昔单抗治疗中重度甲状腺相关眼病的疗效。方法:检索中国知网(CNKI)、万方、维普、中国生物医学、PubMed、Web of Science、OVID、Corhone Library、ClinicalTrial.gov等数据库从建库至2019-12-31发表的关于利妥昔单抗治疗中重度甲状腺相关眼病的临床研究。以治疗前后甲状腺相关眼病的临床活动评分为疗效的主要判定指标。将检索到的文献应用RevMan 5.3统计学软件进行分析。结果:纳入了6项研究61例患者,其中2项为随机对照试验,4项为队列研究。Meta分析显示,应用利妥昔单抗治疗中重度甲状腺相关眼病,可使患者的临床活动评分显著降低[SMD=-5.04,95%CI(-7.08^-3.01),P<0.00001]。结论:利妥昔单抗可使中重度甲状腺相关眼病患者的临床活动评分显著下降,对疾病的控制有良好效果。展开更多
Internet of Things (IoT) has attracted extensive interest from both academia and industries, and is recognized as an ultimate infrastructure to connect everything at anytime and anywhere. The implementation of IoT gen...Internet of Things (IoT) has attracted extensive interest from both academia and industries, and is recognized as an ultimate infrastructure to connect everything at anytime and anywhere. The implementation of IoT generally faces the challenges from energy constraint and implementation cost. In this paper, we will introduce a new green communication paradigm, the ambient backscatter (AmBC), that could utilize the environmental wireless signals for both powering a tiny-cost device and backscattering the information symbols. Specifically, we will present the basic principles of AmBC, analyze its features and advantages, suggest its open problems, and predict its potential applications for our future IoT.展开更多
In recent years,graphics processing units(GPUs)have been applied to accelerate Monte Carlo(MC)simulations for proton dose calculation in radiotherapy.Nonetheless,current GPU platforms,such as Compute Unified Device Ar...In recent years,graphics processing units(GPUs)have been applied to accelerate Monte Carlo(MC)simulations for proton dose calculation in radiotherapy.Nonetheless,current GPU platforms,such as Compute Unified Device Architecture(CUDA)and Open Computing Language(OpenCL),suffer from cross-platform limitation or relatively high programming barrier.However,the Taichi toolkit,which was developed to overcome these difficulties,has been successfully applied to high-performance numerical computations.Based on the class II condensed history simulation scheme with various proton-nucleus interactions,we developed a GPU-accelerated MC engine for proton transport using the Taichi toolkit.Dose distributions in homogeneous and heterogeneous geometries were calculated for 110,160,and 200 MeV protons and were compared with those obtained by full MC simulations using TOPAS.The gamma passing rates were greater than 0.99 and 0.95 with criteria of 2 mm,2%and 1 mm,1%,respectively,in all the benchmark tests.Moreover,the calculation speed was at least 5800 times faster than that of TOPAS,and the number of lines of code was approximately 10 times less than those of CUDA or OpenCL.Our study provides a highly accurate,efficient,and easy-to-use proton dose calculation engine for fast prototyping,beamlet calculation,and education purposes.展开更多
Pests detecting is an important research subject in grain storage field.In the past decades,many edge detection methods have been applied to the edge detection of stored grain pests.Although some of them can realize t...Pests detecting is an important research subject in grain storage field.In the past decades,many edge detection methods have been applied to the edge detection of stored grain pests.Although some of them can realize the stored grain pests detecting,precision and robustness are not good enough.Spectral residual(SR)saliency edge detection defines the logarithmic spectrumof image as novelty part of the image information.The remaining spectrumis converted to the airspace to obtain edge detection results.SR algorithm is completely based on frequency domain processing.It not only can effectively simplify the target detection algorithm,but also can improve the effectiveness of target recognition.The experimental results show that the edge results of stored grain pests detected by SR method are effective and stable.展开更多
文摘目的:通过文献荟萃分析评价利妥昔单抗治疗中重度甲状腺相关眼病的疗效。方法:检索中国知网(CNKI)、万方、维普、中国生物医学、PubMed、Web of Science、OVID、Corhone Library、ClinicalTrial.gov等数据库从建库至2019-12-31发表的关于利妥昔单抗治疗中重度甲状腺相关眼病的临床研究。以治疗前后甲状腺相关眼病的临床活动评分为疗效的主要判定指标。将检索到的文献应用RevMan 5.3统计学软件进行分析。结果:纳入了6项研究61例患者,其中2项为随机对照试验,4项为队列研究。Meta分析显示,应用利妥昔单抗治疗中重度甲状腺相关眼病,可使患者的临床活动评分显著降低[SMD=-5.04,95%CI(-7.08^-3.01),P<0.00001]。结论:利妥昔单抗可使中重度甲状腺相关眼病患者的临床活动评分显著下降,对疾病的控制有良好效果。
基金supported in part by National Key R&D Program of China under Grant 2016YFE0200900part by Scientific Research Program of Beijing Municipal Commission of Education under Grant KM201910853003part by Major projects of Beijing Municipal Science and Technology Commission under Grant Z181100003218010
文摘Internet of Things (IoT) has attracted extensive interest from both academia and industries, and is recognized as an ultimate infrastructure to connect everything at anytime and anywhere. The implementation of IoT generally faces the challenges from energy constraint and implementation cost. In this paper, we will introduce a new green communication paradigm, the ambient backscatter (AmBC), that could utilize the environmental wireless signals for both powering a tiny-cost device and backscattering the information symbols. Specifically, we will present the basic principles of AmBC, analyze its features and advantages, suggest its open problems, and predict its potential applications for our future IoT.
基金supported by the National Natural Science Foundation of China (Nos.11735003,11975041,and 11961141004)。
文摘In recent years,graphics processing units(GPUs)have been applied to accelerate Monte Carlo(MC)simulations for proton dose calculation in radiotherapy.Nonetheless,current GPU platforms,such as Compute Unified Device Architecture(CUDA)and Open Computing Language(OpenCL),suffer from cross-platform limitation or relatively high programming barrier.However,the Taichi toolkit,which was developed to overcome these difficulties,has been successfully applied to high-performance numerical computations.Based on the class II condensed history simulation scheme with various proton-nucleus interactions,we developed a GPU-accelerated MC engine for proton transport using the Taichi toolkit.Dose distributions in homogeneous and heterogeneous geometries were calculated for 110,160,and 200 MeV protons and were compared with those obtained by full MC simulations using TOPAS.The gamma passing rates were greater than 0.99 and 0.95 with criteria of 2 mm,2%and 1 mm,1%,respectively,in all the benchmark tests.Moreover,the calculation speed was at least 5800 times faster than that of TOPAS,and the number of lines of code was approximately 10 times less than those of CUDA or OpenCL.Our study provides a highly accurate,efficient,and easy-to-use proton dose calculation engine for fast prototyping,beamlet calculation,and education purposes.
基金financially supported by National Natural Science Foundation of China(No.61871176)Key Scientific and Technological Project of Science and Technology Department of Henan Province(No.172102210030,182102110099)+2 种基金Key Scientific Research Project Program of Universities of Henan Province(No.18B520025)Open Fund of Key Laboratory of Grain Information Processing and Control(No.KFJJ-2018-102)supported by Collaborative Innovation Center of Grain Storage and Security of Henan Province
文摘Pests detecting is an important research subject in grain storage field.In the past decades,many edge detection methods have been applied to the edge detection of stored grain pests.Although some of them can realize the stored grain pests detecting,precision and robustness are not good enough.Spectral residual(SR)saliency edge detection defines the logarithmic spectrumof image as novelty part of the image information.The remaining spectrumis converted to the airspace to obtain edge detection results.SR algorithm is completely based on frequency domain processing.It not only can effectively simplify the target detection algorithm,but also can improve the effectiveness of target recognition.The experimental results show that the edge results of stored grain pests detected by SR method are effective and stable.
