目的分析人工智能(artificial intelligence,AI)应用于老年人跌倒的研究热点和趋势,以期为我国老年跌倒研究提供思路。方法在Web of Science与中国知网中检索AI应用于老年人跌倒的相关文献,使用Excel分析发文趋势、CiteSpace对关键词进...目的分析人工智能(artificial intelligence,AI)应用于老年人跌倒的研究热点和趋势,以期为我国老年跌倒研究提供思路。方法在Web of Science与中国知网中检索AI应用于老年人跌倒的相关文献,使用Excel分析发文趋势、CiteSpace对关键词进行可视化分析。结果最终获得515篇英文文献、96篇中文文献。年发文量总体呈上升趋势。研究热点显示AI在老年人跌倒预测、检测及预防方面备受关注。结论近年来AI应用于老年人跌倒的研究热度持续增加,我国在该领域的发展滞后于国外。未来可在把握国际热点基础上,深化护理与AI领域合作,探索适宜我国国情的老年人精准跌倒预防与管理策略。展开更多
Gut microbiota plays a crucial role in the pathophysiology of depression.This study aimed to explore the antidepressant effect of mature whole Citrus aurantium fruit extract(FEMC)in the chronic unpredictable mild stre...Gut microbiota plays a crucial role in the pathophysiology of depression.This study aimed to explore the antidepressant effect of mature whole Citrus aurantium fruit extract(FEMC)in the chronic unpredictable mild stress(CUMS)model.The behavioral tests were applied to assess antidepressant effect and 16S rRNA sequencing was used to analyze the changes of gut microbiota.The results showed that the major components of FEMC were naringin and neohesperidin and significantly increased the sucrose preference index of the mice.FEMC also could reduce the feeding latency in an open field test and the rest time in a novelty suppressed feeding test.In addition,FEMC could increase CUMS-induced reduction in the levels of BDNF,PSD95,and SYN in the hippocampus.Moreover,FEMC intervention slightly decreased the ratio of Firmicutes to Bacteroidota.Meanwhile,FEMC reduced the abundance of the Prevotellaceae_Ga6A1_group,[Ruminococcus]_torques_group,which have been reported to be closely related to inflammation.Bioinformatics analysis revealed that mitogen-activated protein kinase(MAPK)signaling pathway and lipopolysaccharide biosynthesis were involved in the anti-inflammatory effect of FEMC in the CUMS animal model.Finally,the ELISA results showed that FEMC could significantly reduce the expression of pro-inflammatory cytokines IL-6 and TNF-αin the serum of depressive mice.Our results suggest FEMC can am eliorate depressive behavior by i nhibiting gut microbiota-mediated inflammation in mice.展开更多
文章通过三维模拟平台,对汽车起重机的吊装作业进行了仿真模拟。使用地理信息系统(geographic information system, GIS)和建筑信息模型(building information modeling, BIM)技术建立了汽车起重机模型,对吊装操作进行了拆解计算,实现...文章通过三维模拟平台,对汽车起重机的吊装作业进行了仿真模拟。使用地理信息系统(geographic information system, GIS)和建筑信息模型(building information modeling, BIM)技术建立了汽车起重机模型,对吊装操作进行了拆解计算,实现了对吊装过程的精确模拟。考虑到安全距离限制,计算合适的安全站位区域,通过分析仿真模拟结果和出具吊装分析报告,为实际吊装作业提供了科学依据和指导,完成了吊装作业模拟仿真流程设计,实现了对吊装作业的高效预演。展开更多
文摘目的分析人工智能(artificial intelligence,AI)应用于老年人跌倒的研究热点和趋势,以期为我国老年跌倒研究提供思路。方法在Web of Science与中国知网中检索AI应用于老年人跌倒的相关文献,使用Excel分析发文趋势、CiteSpace对关键词进行可视化分析。结果最终获得515篇英文文献、96篇中文文献。年发文量总体呈上升趋势。研究热点显示AI在老年人跌倒预测、检测及预防方面备受关注。结论近年来AI应用于老年人跌倒的研究热度持续增加,我国在该领域的发展滞后于国外。未来可在把握国际热点基础上,深化护理与AI领域合作,探索适宜我国国情的老年人精准跌倒预防与管理策略。
基金supported by the National Key Research and Development Program of China(2022YFD2100804)the Natural Science Foundation of ChangSha(kq2202334)+1 种基金Agricultural Science and Technology Innovation Fund project of Hunan Province(2022CX02,2023CX23)Science and Technology Innovation&Entrepreneur Team of Hunan Kanglu Bio-medicine.
文摘Gut microbiota plays a crucial role in the pathophysiology of depression.This study aimed to explore the antidepressant effect of mature whole Citrus aurantium fruit extract(FEMC)in the chronic unpredictable mild stress(CUMS)model.The behavioral tests were applied to assess antidepressant effect and 16S rRNA sequencing was used to analyze the changes of gut microbiota.The results showed that the major components of FEMC were naringin and neohesperidin and significantly increased the sucrose preference index of the mice.FEMC also could reduce the feeding latency in an open field test and the rest time in a novelty suppressed feeding test.In addition,FEMC could increase CUMS-induced reduction in the levels of BDNF,PSD95,and SYN in the hippocampus.Moreover,FEMC intervention slightly decreased the ratio of Firmicutes to Bacteroidota.Meanwhile,FEMC reduced the abundance of the Prevotellaceae_Ga6A1_group,[Ruminococcus]_torques_group,which have been reported to be closely related to inflammation.Bioinformatics analysis revealed that mitogen-activated protein kinase(MAPK)signaling pathway and lipopolysaccharide biosynthesis were involved in the anti-inflammatory effect of FEMC in the CUMS animal model.Finally,the ELISA results showed that FEMC could significantly reduce the expression of pro-inflammatory cytokines IL-6 and TNF-αin the serum of depressive mice.Our results suggest FEMC can am eliorate depressive behavior by i nhibiting gut microbiota-mediated inflammation in mice.
文摘文章通过三维模拟平台,对汽车起重机的吊装作业进行了仿真模拟。使用地理信息系统(geographic information system, GIS)和建筑信息模型(building information modeling, BIM)技术建立了汽车起重机模型,对吊装操作进行了拆解计算,实现了对吊装过程的精确模拟。考虑到安全距离限制,计算合适的安全站位区域,通过分析仿真模拟结果和出具吊装分析报告,为实际吊装作业提供了科学依据和指导,完成了吊装作业模拟仿真流程设计,实现了对吊装作业的高效预演。
