目的·分析主动脉缩窄(coarctation of the aorta,CoA)端侧吻合纠治术后患儿的神经系统预后。方法·收集2017年1月1日至2021年12月31日于上海交通大学医学院附属上海儿童医学中心行CoA端侧吻合纠治术患儿的手术及神经系统随访资...目的·分析主动脉缩窄(coarctation of the aorta,CoA)端侧吻合纠治术后患儿的神经系统预后。方法·收集2017年1月1日至2021年12月31日于上海交通大学医学院附属上海儿童医学中心行CoA端侧吻合纠治术患儿的手术及神经系统随访资料,包括磁共振成像(magnetic resonance imaging,MRI)和Griffiths精神发育量表评分。根据Griffiths精神发育量表的分量表评分,评估患儿神经系统各方面预后情况。通过比较MRI和Griffiths精神发育量表评分结果正常与异常患儿的临床资料,分析2种检查结果之间的相关性,以及检查结果与患儿是否实施体外循环(cardiopulmonary bypass,CPB)及CPB方式的相关性。结果·纳入单纯或合并简单心内畸形的CoA患儿27例。有MRI检查结果者25例,其中检查结果异常者5例(20.0%);有Griffiths精神发育量表评分者26例,其中评分异常的患儿21例(80.77%),包括听力-语言评分异常18例、表现评分异常12例。MRI和Griffiths精神发育量表检查结果异常与是否实施CPB无相关性(P=0.341,P=1.000)。MRI检查结果和Griffiths精神发育量表评分显示,在接受CPB的病例中,中低温组神经系统预后无异常的患儿占所有无异常者的比例较高,分别为80.00%与100.00%。结论·CoA端侧吻合纠治术后患儿发生神经系统异常的比例较高,其中影响较大的是听力-语言和表现能力;CPB不是直接引起神经系统预后不良的危险因素,在中低温下实施可能有利于保护神经系统。展开更多
The preferential oxidation of CO(CO-PROX)reaction is a cost-effective method for eliminating trace amounts of CO from the fuel H2.Pt-based catalysts have been extensively studied for COPROX,with their activity influen...The preferential oxidation of CO(CO-PROX)reaction is a cost-effective method for eliminating trace amounts of CO from the fuel H2.Pt-based catalysts have been extensively studied for COPROX,with their activity influenced by the morphology of the support.Hydrothermal synthesis was employed to produce different morphologies ofγ-Al_(2)O_(3):flower-likeγ-Al_(2)O_(3)(f)exposing(110)crystal faces,sheet-likeγ-Al_(2)O_(3)(s)revealing(100)crystal faces,and rod-likeγ-Al_(2)O_(3)(r)displaying(111)crystal faces,followed by loading PtCo nanoparticles.The exposed crystal faces of the support impact the alloying degree of the PtCo nanoparticles,and an increase in the alloying degree correlates with enhanced catalyst reactivity.Pt_(3)Co intermetallic compounds were identified onγ-Al_(2)O_(3)(f)exposing(110)crystal faces,and PtCo/γ-Al_(2)O_(3)(f)showed high catalytic activity in the CO-PROX reaction,achieving 100%CO conversion across a broad temperature range of 50−225°C.In contrast,only partial alloying of PtCo was observed onγ-Al_(2)O_(3)(s).Furthermore,no alloying between Pt and Co occurred in PtCo/γ-Al_(2)O_(3)(r),resulting in a reaction rate at 50°C that was merely 11%of that of PtCo/γ-Al_(2)O_(3)(f).The formation of Pt3Co intermetallic compounds led to a more oxidized state of Pt,which significantly diminished the adsorption of CO on Pt and augmented the active oxygen species,thereby facilitating the selective oxidation of CO.展开更多
For space-borne gravitational wave detection missions based on the heterodyne interferometry principle,tilt-to-length(TTL)coupling noise is an important optical noise source,significantly influencing the accuracy of t...For space-borne gravitational wave detection missions based on the heterodyne interferometry principle,tilt-to-length(TTL)coupling noise is an important optical noise source,significantly influencing the accuracy of the measurement system.We present a method for analyzing TTL coupling noise under the joint influence of multiple factors.An equivalent simulated optical bench for the test mass interferometer was designed,and Gaussian beam tracing was adopted to simulate beam propagation.By simulating the interference signal,it can analyze the impact of various factors on the TTL coupling noise,including positional,beam parameters,detector parameters,and signal definition factors.On this basis,a random parameter space composed of multiple influential factors was constructed within a range satisfying the analysis requirement,and the corresponding simulation results from random sampling were evaluated via variance-based global sensitivity analysis.The calculated results of the main and total effect indexes show that the test mass rotation angle and the piston effect(lateral)significantly influence the TTL coupling noise in the test mass interferometer.The analysis provides a qualitative reference for designing and optimizing space-borne laser interferometry systems.展开更多
文摘目的·分析主动脉缩窄(coarctation of the aorta,CoA)端侧吻合纠治术后患儿的神经系统预后。方法·收集2017年1月1日至2021年12月31日于上海交通大学医学院附属上海儿童医学中心行CoA端侧吻合纠治术患儿的手术及神经系统随访资料,包括磁共振成像(magnetic resonance imaging,MRI)和Griffiths精神发育量表评分。根据Griffiths精神发育量表的分量表评分,评估患儿神经系统各方面预后情况。通过比较MRI和Griffiths精神发育量表评分结果正常与异常患儿的临床资料,分析2种检查结果之间的相关性,以及检查结果与患儿是否实施体外循环(cardiopulmonary bypass,CPB)及CPB方式的相关性。结果·纳入单纯或合并简单心内畸形的CoA患儿27例。有MRI检查结果者25例,其中检查结果异常者5例(20.0%);有Griffiths精神发育量表评分者26例,其中评分异常的患儿21例(80.77%),包括听力-语言评分异常18例、表现评分异常12例。MRI和Griffiths精神发育量表检查结果异常与是否实施CPB无相关性(P=0.341,P=1.000)。MRI检查结果和Griffiths精神发育量表评分显示,在接受CPB的病例中,中低温组神经系统预后无异常的患儿占所有无异常者的比例较高,分别为80.00%与100.00%。结论·CoA端侧吻合纠治术后患儿发生神经系统异常的比例较高,其中影响较大的是听力-语言和表现能力;CPB不是直接引起神经系统预后不良的危险因素,在中低温下实施可能有利于保护神经系统。
基金supported by the National Natural Science Foundation of China(22376063,21976057)the Fund of the National Engineering Laboratory for Mobile Source Emission Control Technology(NELMS2020A05)Fundamental Research Funds for the Central Universities.
文摘The preferential oxidation of CO(CO-PROX)reaction is a cost-effective method for eliminating trace amounts of CO from the fuel H2.Pt-based catalysts have been extensively studied for COPROX,with their activity influenced by the morphology of the support.Hydrothermal synthesis was employed to produce different morphologies ofγ-Al_(2)O_(3):flower-likeγ-Al_(2)O_(3)(f)exposing(110)crystal faces,sheet-likeγ-Al_(2)O_(3)(s)revealing(100)crystal faces,and rod-likeγ-Al_(2)O_(3)(r)displaying(111)crystal faces,followed by loading PtCo nanoparticles.The exposed crystal faces of the support impact the alloying degree of the PtCo nanoparticles,and an increase in the alloying degree correlates with enhanced catalyst reactivity.Pt_(3)Co intermetallic compounds were identified onγ-Al_(2)O_(3)(f)exposing(110)crystal faces,and PtCo/γ-Al_(2)O_(3)(f)showed high catalytic activity in the CO-PROX reaction,achieving 100%CO conversion across a broad temperature range of 50−225°C.In contrast,only partial alloying of PtCo was observed onγ-Al_(2)O_(3)(s).Furthermore,no alloying between Pt and Co occurred in PtCo/γ-Al_(2)O_(3)(r),resulting in a reaction rate at 50°C that was merely 11%of that of PtCo/γ-Al_(2)O_(3)(f).The formation of Pt3Co intermetallic compounds led to a more oxidized state of Pt,which significantly diminished the adsorption of CO on Pt and augmented the active oxygen species,thereby facilitating the selective oxidation of CO.
文摘For space-borne gravitational wave detection missions based on the heterodyne interferometry principle,tilt-to-length(TTL)coupling noise is an important optical noise source,significantly influencing the accuracy of the measurement system.We present a method for analyzing TTL coupling noise under the joint influence of multiple factors.An equivalent simulated optical bench for the test mass interferometer was designed,and Gaussian beam tracing was adopted to simulate beam propagation.By simulating the interference signal,it can analyze the impact of various factors on the TTL coupling noise,including positional,beam parameters,detector parameters,and signal definition factors.On this basis,a random parameter space composed of multiple influential factors was constructed within a range satisfying the analysis requirement,and the corresponding simulation results from random sampling were evaluated via variance-based global sensitivity analysis.The calculated results of the main and total effect indexes show that the test mass rotation angle and the piston effect(lateral)significantly influence the TTL coupling noise in the test mass interferometer.The analysis provides a qualitative reference for designing and optimizing space-borne laser interferometry systems.
