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Basic roles of key molecules connected with NMDAR signaling pathway on regulating learning and memory and synaptic plasticity 被引量:18
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作者 Hui Wang rui-yun peng 《Journal of Medical Colleges of PLA(China)》 CAS 2016年第4期212-218,共7页
With key roles in essential brain functions ranging from the long-term potentiation(LTP) to synaptic plasticity,the N-methyl-D-aspartic acid receptor(NMDAR) can be considered as one of the fundamental glutamate recept... With key roles in essential brain functions ranging from the long-term potentiation(LTP) to synaptic plasticity,the N-methyl-D-aspartic acid receptor(NMDAR) can be considered as one of the fundamental glutamate receptors in the central nervous system.The role of NMDA R was first identified in synaptic plasticity and has been extensively studied.Some molecules,such as Ca^(2+),postsynaptic density 95(PSD-95),calcium/calmodulin-dependent protein kinase II(Ca MK II),protein kinase A(PKA),mitogen-activated protein kinase(MAPK) and cyclic adenosine monophosphate(c AMP) responsive element binding protein(CREB),are of special importance in learning and memory.This review mainly focused on the new research of key molecules connected with learning and memory,which played important roles in the NMDAR signaling pathway. 展开更多
关键词 N-methyl-D-aspartic acid receptors Long-term potentiation Synaptic plasticity Learning and memory
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Advances in the biological effects of terahertz wave radiation 被引量:7
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作者 Li Zhao Yan-Hui Hao rui-yun peng 《Journal of Medical Colleges of PLA(China)》 CAS 2014年第3期173-176,共4页
The terahertz(THz) band lies between microwave and infrared rays in wavelength and consists of non-ionizing radiation. Both domestic and foreign research institutions, including the army, have attached considerable im... The terahertz(THz) band lies between microwave and infrared rays in wavelength and consists of non-ionizing radiation. Both domestic and foreign research institutions, including the army, have attached considerable importance to the research and development of THz technology because this radiation exhibits both photon-like and electron-like properties, which grant it considerable application value and potential. With the rapid development of THz technology and related applications, studies of the biological effects of THz radiation have become a major focus in the field of life sciences. Research in this field has only just begun, both at home and abroad. In this paper, research progress with respect to THz radiation, including its biological effects, mechanisms and methods of protection, will be reviewed. 展开更多
关键词 TERAHERTZ RADIATION BIOLOGICAL EFFECTS PROGRESS
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Research progress in the effects of terahertz waves on biomacromolecules 被引量:5
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作者 Liu Sun Li Zhao rui-yun peng 《Military Medical Research》 SCIE CSCD 2022年第1期63-70,共8页
With the rapid development of terahertz technologies,basic research and applications of terahertz waves in biomedicine have attracted increasing attention.The rotation and vibrational energy levels of biomacromolecule... With the rapid development of terahertz technologies,basic research and applications of terahertz waves in biomedicine have attracted increasing attention.The rotation and vibrational energy levels of biomacromolecules fall in the energy range of terahertz waves;thus,terahertz waves might interact with biomacromolecules.Therefore,terahertz waves have been widely applied to explore features of the terahertz spectrum of biomacromolecules.However,the effects of terahertz waves on biomacromolecules are largely unexplored.Although some progress has been reported,there are still numerous technical barriers to clarifying the relation between terahertz waves and biomacromolecules and to realizing the accurate regulation of biological macromolecules by terahertz waves.Therefore,further investigations should be conducted in the future.In this paper,we reviewed terahertz waves and their biomedical research advantages,applications of terahertz waves on biomacromolecules and the effects of terahertz waves on biomacromolecules.These findings will provide novel ideas and methods for the research and application of terahertz waves in the biomedical field. 展开更多
关键词 Terahertz waves BIOMACROMOLECULES EFFECT REVIEW
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Establishment of injury models in studies of biological effects induced by microwave radiation 被引量:4
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作者 Yun-Fei Lai Hao-Yu Wang rui-yun peng 《Military Medical Research》 SCIE CSCD 2021年第2期253-272,共20页
Microwave radiation has been widely used in various fields,such as communication,industry,medical treatment,and military applications.Microwave radiation may cause injuries to both the structures and functions of vari... Microwave radiation has been widely used in various fields,such as communication,industry,medical treatment,and military applications.Microwave radiation may cause injuries to both the structures and functions of various organs,such as the brain,heart,reproductive organs,and endocrine organs,which endanger human health.Therefore,it is both theoretically and clinically important to conduct studies on the biological effects induced by microwave radiation.The successful establishment of injury models is of great importance to the reliability and reproducibility of these studies.In this article,we review the microwave exposure conditions,subjects used to establish injury models,the methods used for the assessment of the injuries,and the indicators implemented to evaluate the success of injury model establishment in studies on biological effects induced by microwave radiation. 展开更多
关键词 Microwave radiation Injury model Biological effects METHODS Biological indicators REVIEW
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Biological effects and mechanisms of shortwave radiation: a review 被引量:7
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作者 Chao Yu rui-yun peng 《Military Medical Research》 SCIE CAS 2018年第1期79-84,共6页
With the increasing knowledge of shortwave radiation,it is widely used in wireless communications,radar observations,industrial manufacturing,and medical treatments.Despite of the benefits from shortwave,these wide ap... With the increasing knowledge of shortwave radiation,it is widely used in wireless communications,radar observations,industrial manufacturing,and medical treatments.Despite of the benefits from shortwave,these wide applications expose humans to the risk of shortwave electromagnetic radiation,which is alleged to cause potential damage to biological systems.This review focused on the exposure to shortwave electromagnetic radiation,considering in vitro,in vivo and epidemiological results that have provided insight into the biological effects and mechanisms of shortwave.Additionally,some protective measures and suggestions are discussed here in the hope of obtaining more benefits from shortwave with fewer health risks. 展开更多
关键词 Shortwave Electromagnetic radiation Biological effects
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Effects and mechanisms of a microcurrent dressing on skin wound healing: a review 被引量:5
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作者 Chao Yu Zong-Qian Hu rui-yun peng 《Journal of Medical Colleges of PLA(China)》 CAS 2014年第3期177-185,共9页
The variety of wound types has resulted in a wide range of wound dressings, with new products frequently being introduced to target different aspects of the wound healing process. The ideal wound dressing should achie... The variety of wound types has resulted in a wide range of wound dressings, with new products frequently being introduced to target different aspects of the wound healing process. The ideal wound dressing should achieve rapid healing at a reasonable cost, with minimal inconvenience to the patient. Microcurrent dressing, a novel wound dressing with inherent electric activity, can generate low-level microcurrents at the device-wound contact surface in the presence of moisture and can provide an advanced wound healing solution for managing wounds. This article offers a review of the effects and mechanisms of the microcurrent dressing on the healing of skin wounds. 展开更多
关键词 Microcurrent dressing Electric stimulation Skin wound healing
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Effects of microwave radiation on brain energy metabolism and related mechanisms 被引量:2
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作者 Yan-Hui Hao Li Zhao rui-yun peng 《Journal of Medical Colleges of PLA(China)》 CAS 2014年第4期235-243,共9页
With the rapid development of electronic technologies, anxiety regarding the potential health hazards induced by microwave radiation(MW) has been growing in recent years. The brain is one of the most sensitive target ... With the rapid development of electronic technologies, anxiety regarding the potential health hazards induced by microwave radiation(MW) has been growing in recent years. The brain is one of the most sensitive target organs for microwave radiation, where mitochondrial injury occurs earlier and more severely than in other organs. Energy metabolism disorders do play an important role during the process of microwave radiation-induced brain damage. In this paper, we will review the biological effects of microwave radiation, the features of brain energy supply and consumption and the effects of microwave radiation on mitochondrial energy metabolism and potential related mechanisms. 展开更多
关键词 Microwave radiation BRAIN Energy metabolism MITOCHONDRIA MECHANISMS
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