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Cyclic mechanical stretch regulates MMPs and TIMPs expression in corneal fibroblasts
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作者 Chengxing Liu pengfei feng +2 位作者 Xiaona Li Xiaojun Wang Weiyi Chen 《医用生物力学》 EI CAS CSCD 北大核心 2013年第S1期7-8,共2页
Laser in situ keratomileusis(LASIK)is a relatively new ophthalmic procedure in refractive surgery.It involves the use of a microkeratome to create a thin corneal flap followed by excimer laser ablation of the corneal ... Laser in situ keratomileusis(LASIK)is a relatively new ophthalmic procedure in refractive surgery.It involves the use of a microkeratome to create a thin corneal flap followed by excimer laser ablation of the corneal stroma and repositioning of the flap.However,complications are bound to occur when a surgical procedure is performed with increasing frequency.In some cases,serious complications such as keratectasia occurred.Risk factors for corneal keratectasia include a thin cornea at baseline,thick corneal flap,excessive ablation,irregular corneal thickness,diverse ablation rates,preexisting keratoconus or form fruste keratoconus,and high intraocular pressure(IOP)~[1].It is evident from incisional refractive surgery that the cornea is not mechanically inert.The mechanical environment of the central corneal tissue is also altered un- 展开更多
关键词 CORNEAL KERATOMILEUSIS ablation INTRAOCULAR STRETCH altered refractive diverse TIMPS mechanically
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