It is estimated that approximately one in ten people over the age of 80 may suffer from cardiac amyloidosis(CA),a disease in which various aging-related factors,such as increased oxidative stress,can promote abnormal ...It is estimated that approximately one in ten people over the age of 80 may suffer from cardiac amyloidosis(CA),a disease in which various aging-related factors,such as increased oxidative stress,can promote abnormal protein folding and the formation of amyloid deposits in the heart.Over the long term,this tends to impair cardiac function,increasing the risk of developing cardiac conduction disorders,atrial fibrillation,thromboembolic events,heart failure(HF),and/or ventricular dysfunction.^([1,2])展开更多
文摘It is estimated that approximately one in ten people over the age of 80 may suffer from cardiac amyloidosis(CA),a disease in which various aging-related factors,such as increased oxidative stress,can promote abnormal protein folding and the formation of amyloid deposits in the heart.Over the long term,this tends to impair cardiac function,increasing the risk of developing cardiac conduction disorders,atrial fibrillation,thromboembolic events,heart failure(HF),and/or ventricular dysfunction.^([1,2])