Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the inju...Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the injury and pathophysiological mechanisms underlying PCAS remain unclear.Experimental animal models are valuable tools for exploring the etiology,pathogenesis,and potential interventions for CA and PCAS.Current CA animal models include electrical induction of ventricular fibrillation(VF),myocardial infarction,high potassium,asphyxia,and hemorrhagic shock.Although these models do not fully replicate the complexity of clinical CA,the mechanistic insights they provide remain highly relevant,including post-CA brain injury(PCABI),post-CA myocardial dysfunction(PAMD),systemic ischaemia/reperfusion injury(IRI),and the persistent precipitating pathology.Summarizing the methods of establishing CA models,the challenges encountered in the modeling process,and the mechanisms of PCAS can provide a foundation for developing standardized CA modeling protocols.展开更多
灾难医学是一门交叉学科,指利用医学、管理、信息、工程等知识,及时为受灾群众提供医疗服务。灾难的频繁发生促使了灾难医学的发展,随着灾难医学相关的研究文献越来越多,采用文献计量学的方法探索灾难医学领域的领先参与者以及热点研究...灾难医学是一门交叉学科,指利用医学、管理、信息、工程等知识,及时为受灾群众提供医疗服务。灾难的频繁发生促使了灾难医学的发展,随着灾难医学相关的研究文献越来越多,采用文献计量学的方法探索灾难医学领域的领先参与者以及热点研究方向,总结灾难医学的发展特点。该文收集了Web of Science Core Collection数据库中与灾难医学相关的1858篇文章,使用Bibliometrix、VOSviewer、CiteSpace分析文献计量指标,包括国家、机构和作者的贡献以及研究热点,结果表明:欧美国家、中国、日本在灾难医学领域有较高的影响力;灾难医学的研究方向多种多样,灾难医学管理这一研究方向的生命力很强,除此以外,还有灾害护理、灾难医学课程教育、心理健康、生理健康、灾后影响、灾难流行病等研究方向。未来,中国灾难医学的发展还需要提高重视程度,加强全球合作,重视科研创新,才能取得长足进步。展开更多
基金supported by the National Key Research and Development Program(2021YFC3002205)the Postgraduate Research and Innovation Program of Tianjin Municipal Education Commission(2022BKY113),China.
文摘Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the injury and pathophysiological mechanisms underlying PCAS remain unclear.Experimental animal models are valuable tools for exploring the etiology,pathogenesis,and potential interventions for CA and PCAS.Current CA animal models include electrical induction of ventricular fibrillation(VF),myocardial infarction,high potassium,asphyxia,and hemorrhagic shock.Although these models do not fully replicate the complexity of clinical CA,the mechanistic insights they provide remain highly relevant,including post-CA brain injury(PCABI),post-CA myocardial dysfunction(PAMD),systemic ischaemia/reperfusion injury(IRI),and the persistent precipitating pathology.Summarizing the methods of establishing CA models,the challenges encountered in the modeling process,and the mechanisms of PCAS can provide a foundation for developing standardized CA modeling protocols.
文摘灾难医学是一门交叉学科,指利用医学、管理、信息、工程等知识,及时为受灾群众提供医疗服务。灾难的频繁发生促使了灾难医学的发展,随着灾难医学相关的研究文献越来越多,采用文献计量学的方法探索灾难医学领域的领先参与者以及热点研究方向,总结灾难医学的发展特点。该文收集了Web of Science Core Collection数据库中与灾难医学相关的1858篇文章,使用Bibliometrix、VOSviewer、CiteSpace分析文献计量指标,包括国家、机构和作者的贡献以及研究热点,结果表明:欧美国家、中国、日本在灾难医学领域有较高的影响力;灾难医学的研究方向多种多样,灾难医学管理这一研究方向的生命力很强,除此以外,还有灾害护理、灾难医学课程教育、心理健康、生理健康、灾后影响、灾难流行病等研究方向。未来,中国灾难医学的发展还需要提高重视程度,加强全球合作,重视科研创新,才能取得长足进步。
