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红鳘鱼胶胶原蛋白对D-半乳糖致衰老小鼠皮肤的抗衰老作用研究 被引量:2
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作者 钟碧銮 廖静如 +3 位作者 黄泽敏 姚若然 杜冰 张宇 《日用化学工业(中英文)》 CAS 北大核心 2024年第5期550-557,共8页
以红鳘鱼胶为原料,酸酶法提取胶原蛋白,通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)、氨基酸组成分析等方法进行理化性质分析,并以D-半乳糖建立衰老小鼠模型,探究其对小鼠皮肤含水量、羟脯氨酸含量、皮肤病理形态和抗氧化活性的... 以红鳘鱼胶为原料,酸酶法提取胶原蛋白,通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)、氨基酸组成分析等方法进行理化性质分析,并以D-半乳糖建立衰老小鼠模型,探究其对小鼠皮肤含水量、羟脯氨酸含量、皮肤病理形态和抗氧化活性的影响。结果表明,胶原蛋白由2条α链与1条β链组成,为典型的Ⅰ型胶原蛋白,以甘氨酸、丙氨酸、谷氨酸、脯氨酸为特征氨基酸,分别占总氨基酸含量13.890%,8.601%,7.650%和7.124%,且不含色氨酸;动物实验结果表明,经D-半乳糖造模后,MN组小鼠皮肤粗糙、松弛,皱纹数量增多,相较于CN组皮肤水分含量降低了13.52%,羟脯氨酸含量降低了26.20%,抗氧化能力降低,小鼠皮肤真皮层变薄,胶原纤维、弹性纤维含量降低,部分明显断开;红鳘鱼胶胶原蛋白干预后,能够显著改善由于D-半乳糖造成的小鼠背部皮肤水分流失,增强小鼠皮肤组织氧化应激抵抗力,胶原蛋白组皮肤结构基本恢复,皮肤胶原纤维和弹力纤维含量升高,Ⅰ/Ⅲ型胶原蛋白比例升高了9.79%。综上分析,通过红鳘鱼胶制备的胶原蛋白可延缓D-半乳糖引起的皮肤衰老,可为胶原蛋白在化妆品领域的高值化利用提供依据。 展开更多
关键词 胶原蛋白 电泳 氨基酸组成 D-半乳糖 抗衰老
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Independent component analysis to physical-layer network coding over wireless fading channels
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作者 bing du Xiaoming Tao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2013年第2期196-203,共8页
A new combinational technology is proposed,which is feasible to apply physical-layer network coding(PNC) to wireless fading channels by employing the harmful interference strategically.The key step of PNC is that so... A new combinational technology is proposed,which is feasible to apply physical-layer network coding(PNC) to wireless fading channels by employing the harmful interference strategically.The key step of PNC is that sources broadcast signals simultaneously without orthogonal scheduling.Naturally,the signals overlap in the free space at the receivers.Since the signals from different sources are mutual independent,rooted on this rational assumption,an enhanced joint diagonalization separation named altering row diagonalization(ARD) algorithm is exploited to separate these signals by maximizing the cost function measuring independence among them.This ARD PNC(APNC) methodology provides an innovative way to implement signal-level network coding at the presence of interference and without any priori information about channels in fading environments.In conclusions,the proposed APNC performs well with higher bandwidth utility and lower error rate. 展开更多
关键词 physical-layer network coding (PNC) independentcomponent analysis (ICA) joint diagonalization network coding cooperative communications.
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