目的评估早期促进肠道蠕动对早产儿喂养耐受性的改善效果。方法选取2014年5月—2015年6月上海市儿童医院新生儿科早产儿病房患儿123例,入选104例。根据入院日期将入选病例方便分为对照组50例及观察组54例,两组在胎龄、出生体质量、1 min...目的评估早期促进肠道蠕动对早产儿喂养耐受性的改善效果。方法选取2014年5月—2015年6月上海市儿童医院新生儿科早产儿病房患儿123例,入选104例。根据入院日期将入选病例方便分为对照组50例及观察组54例,两组在胎龄、出生体质量、1 min及5 min Apgar评分等方面基线一致。对照组采用静脉营养联合经肠道早产儿液体配方乳喂养,观察组在此基础上增加每日一次的腹部按摩。通过比较两组胎粪排尽时间、恢复至出生体质量时间、经肠道内喂养每日摄入热卡达到501.6 k J/kg(全肠道喂养)的时间,来评估早产儿喂养耐受情况。结果观察组患儿胎粪排尽时间明显短于对照组,差异有统计学意义(F=11.542,P<0.001);恢复至出生体质量时间明显短于对照组,差异有统计学意义(F=7.76,P=0.006);经肠道内喂养达到每日摄入热卡501.6 k J/kg时间短于对照组,差异有统计学意义(F=6.547,P<0.01)。结论对早产儿进行腹部按摩的干预方法能显著减少早产儿喂养不耐受情况的发生,对早产儿的生长发育具有促进意义。展开更多
Large-scale non-thermal plasmas generated by nanosecond-pulse discharges have been used in various applications, including surface treatment, biomedical treatment, flow con- trol etc. In this paper, atmospheric-pressu...Large-scale non-thermal plasmas generated by nanosecond-pulse discharges have been used in various applications, including surface treatment, biomedical treatment, flow con- trol etc. In this paper, atmospheric-pressure diffuse discharge was produced by a homemade nanosecond-pulse generator with a full width at half maximum of 100 ns and a rise time of 70 ns. In order to increase the discharge area, multi-needle electrodes with a 3~3 array were designed. The electrical characteristics of the diffuse discharge array and optical images were investigated by the voltage-current waveforms and discharge images. The experimental results showed that the intensity of diffuse discharges in the center was significantly weaker than those at the margins, resulting in an inhomogeneous spatial uniformity in the diffuse discharge array. Simulation of the electric field showed that the inhomogeneous spatial uniformity was caused by the non-uniform distribution of the electric field in the diffuse discharge array. Moreover, the spatial uniformity of the diffuse discharge array could be improved by increasing the length of the needle in the centre of the array. Finally, the experimental results confirmed the simulation results, and the spatial uniformity of the nanosecond-pulse diffuse discharge array was significantly improved.展开更多
文摘目的评估早期促进肠道蠕动对早产儿喂养耐受性的改善效果。方法选取2014年5月—2015年6月上海市儿童医院新生儿科早产儿病房患儿123例,入选104例。根据入院日期将入选病例方便分为对照组50例及观察组54例,两组在胎龄、出生体质量、1 min及5 min Apgar评分等方面基线一致。对照组采用静脉营养联合经肠道早产儿液体配方乳喂养,观察组在此基础上增加每日一次的腹部按摩。通过比较两组胎粪排尽时间、恢复至出生体质量时间、经肠道内喂养每日摄入热卡达到501.6 k J/kg(全肠道喂养)的时间,来评估早产儿喂养耐受情况。结果观察组患儿胎粪排尽时间明显短于对照组,差异有统计学意义(F=11.542,P<0.001);恢复至出生体质量时间明显短于对照组,差异有统计学意义(F=7.76,P=0.006);经肠道内喂养达到每日摄入热卡501.6 k J/kg时间短于对照组,差异有统计学意义(F=6.547,P<0.01)。结论对早产儿进行腹部按摩的干预方法能显著减少早产儿喂养不耐受情况的发生,对早产儿的生长发育具有促进意义。
基金supported by National Natural Science Foundation of China(Nos.51222701,51477164)the National Basic Research Program of China(No.2014CB239505-3)
文摘Large-scale non-thermal plasmas generated by nanosecond-pulse discharges have been used in various applications, including surface treatment, biomedical treatment, flow con- trol etc. In this paper, atmospheric-pressure diffuse discharge was produced by a homemade nanosecond-pulse generator with a full width at half maximum of 100 ns and a rise time of 70 ns. In order to increase the discharge area, multi-needle electrodes with a 3~3 array were designed. The electrical characteristics of the diffuse discharge array and optical images were investigated by the voltage-current waveforms and discharge images. The experimental results showed that the intensity of diffuse discharges in the center was significantly weaker than those at the margins, resulting in an inhomogeneous spatial uniformity in the diffuse discharge array. Simulation of the electric field showed that the inhomogeneous spatial uniformity was caused by the non-uniform distribution of the electric field in the diffuse discharge array. Moreover, the spatial uniformity of the diffuse discharge array could be improved by increasing the length of the needle in the centre of the array. Finally, the experimental results confirmed the simulation results, and the spatial uniformity of the nanosecond-pulse diffuse discharge array was significantly improved.