This paper derives the variance of the information content and develops its statistical inference method. We describe the relations between information content and sensitivity, specificity, efficiency, prevalence rate...This paper derives the variance of the information content and develops its statistical inference method. We describe the relations between information content and sensitivity, specificity, efficiency, prevalence rate. If sensitivity, specificity and efficiency are fixed, the closer to 0. 5 the prevalence rate is, the more the information content. If prevalence rate and efficiency are fixed, the closer to each other the sensitivity and specificity are, the more the information content. We compare the power of information content method, efficiecy test, Youden's index test and kappa coefficient method. The information content method has higher power than the other methods in most conditions. It is especially sensitive to the difference between two sensitivities. It comes to conclusion that the information content method has more virtues than the other methods mentioned in this paper.展开更多
This paper discusses how the positive and negative predictive values vary withcontrary variations of sensitivity and specificity at a certain disease prevalence.Let thesensitiviy be Se and the specificity be Sp at the...This paper discusses how the positive and negative predictive values vary withcontrary variations of sensitivity and specificity at a certain disease prevalence.Let thesensitiviy be Se and the specificity be Sp at the initial cutoff point,correspondingly Se’and Sp’ at a new cutoff point:A=Se’/Se:B-(1-Sp’)/(1-Sp):C=Sp’/Sp;D=(I-Se’)/(I-Se).Moving the cutoff point from the initial point to the new point,if the contrary variationsof the sensitivity and specificity satisfy the inequality A】B,then the positive predictivevalue increases,otherwise it decreases or remains unchanged.If the variations satisfy theinequality C】D,then the negative prcdictive value increases,otherwise it decreasses or re-mains unchanged.展开更多
Objective: To assess the reliability and validity of the Inpotient Satisfaction Questionnaire (IPSQ) on the basis of a pilot survey. Methods: The subjects were 900 patients discharged from 3 general hospitals in Guang...Objective: To assess the reliability and validity of the Inpotient Satisfaction Questionnaire (IPSQ) on the basis of a pilot survey. Methods: The subjects were 900 patients discharged from 3 general hospitals in Guangzhou. Mail survey was employed. The reliability was evaluated by internal consistency and test-retest reliability. The validity was assessed by content validity and construct validity. Results: The response rates were 30% for the test, 47% for the retest and 93.2% for the total items. High haiability of IPSQ was proved by Cronbach’s a of 0. 92, and no sighficant difference (P = 0. 183) and whereas conspicuous correlation (r = 0. 812, P < 0. 000 1 ) between test and retest were shown. Content validity was supported by factor loading. Convergent and discriminant validity was strongly supported by the fact that the maximum interscale correlation was less than the internal consistency of individual dimension. Conclusion:The IPSQ was reliable and valid.展开更多
The significant decrease in tumor recurrence caused by combined hyperthermia (local water bath) with cryotherapy has previously been shown. This study demonstrated an in vivo additive interaction of local microwave di...The significant decrease in tumor recurrence caused by combined hyperthermia (local water bath) with cryotherapy has previously been shown. This study demonstrated an in vivo additive interaction of local microwave diathermy (hyperthermia, 42±0.5℃, 20 min. ) and liquid nitrogen treatment (cryotherapy,-180℃, 3 min. ) against intraperitoneally implanted sarcoma 180 in ICR mice. Local hyperthermia was produced by applicating 2450 MHz microwave to the region of the tumor without induction of significant whole body hyperthermia.Both hyperthermia and cryotherapy were delivered as a single dose individually on day 1 and day 2. The analysis of the tumor size curves showed that all of the treatments had more significant effect on sarcoma 180 than on the control group (P < 0. 0001 ). The optimal sequence of the combined therapies found in the experiment was cryotherapy→hyperthermia (CH) (P<0. 0001). Weights of the tumors excised from the mice on day 11 showed that the combined therapies (cryotherapy→hyperthermia or hyperthermia→cryotherapy) were more effective on sarcoma 180 than hyperthermia or cryotherapy used alone(P<0.01).展开更多
文摘This paper derives the variance of the information content and develops its statistical inference method. We describe the relations between information content and sensitivity, specificity, efficiency, prevalence rate. If sensitivity, specificity and efficiency are fixed, the closer to 0. 5 the prevalence rate is, the more the information content. If prevalence rate and efficiency are fixed, the closer to each other the sensitivity and specificity are, the more the information content. We compare the power of information content method, efficiecy test, Youden's index test and kappa coefficient method. The information content method has higher power than the other methods in most conditions. It is especially sensitive to the difference between two sensitivities. It comes to conclusion that the information content method has more virtues than the other methods mentioned in this paper.
文摘This paper discusses how the positive and negative predictive values vary withcontrary variations of sensitivity and specificity at a certain disease prevalence.Let thesensitiviy be Se and the specificity be Sp at the initial cutoff point,correspondingly Se’and Sp’ at a new cutoff point:A=Se’/Se:B-(1-Sp’)/(1-Sp):C=Sp’/Sp;D=(I-Se’)/(I-Se).Moving the cutoff point from the initial point to the new point,if the contrary variationsof the sensitivity and specificity satisfy the inequality A】B,then the positive predictivevalue increases,otherwise it decreases or remains unchanged.If the variations satisfy theinequality C】D,then the negative prcdictive value increases,otherwise it decreasses or re-mains unchanged.
文摘Objective: To assess the reliability and validity of the Inpotient Satisfaction Questionnaire (IPSQ) on the basis of a pilot survey. Methods: The subjects were 900 patients discharged from 3 general hospitals in Guangzhou. Mail survey was employed. The reliability was evaluated by internal consistency and test-retest reliability. The validity was assessed by content validity and construct validity. Results: The response rates were 30% for the test, 47% for the retest and 93.2% for the total items. High haiability of IPSQ was proved by Cronbach’s a of 0. 92, and no sighficant difference (P = 0. 183) and whereas conspicuous correlation (r = 0. 812, P < 0. 000 1 ) between test and retest were shown. Content validity was supported by factor loading. Convergent and discriminant validity was strongly supported by the fact that the maximum interscale correlation was less than the internal consistency of individual dimension. Conclusion:The IPSQ was reliable and valid.
文摘The significant decrease in tumor recurrence caused by combined hyperthermia (local water bath) with cryotherapy has previously been shown. This study demonstrated an in vivo additive interaction of local microwave diathermy (hyperthermia, 42±0.5℃, 20 min. ) and liquid nitrogen treatment (cryotherapy,-180℃, 3 min. ) against intraperitoneally implanted sarcoma 180 in ICR mice. Local hyperthermia was produced by applicating 2450 MHz microwave to the region of the tumor without induction of significant whole body hyperthermia.Both hyperthermia and cryotherapy were delivered as a single dose individually on day 1 and day 2. The analysis of the tumor size curves showed that all of the treatments had more significant effect on sarcoma 180 than on the control group (P < 0. 0001 ). The optimal sequence of the combined therapies found in the experiment was cryotherapy→hyperthermia (CH) (P<0. 0001). Weights of the tumors excised from the mice on day 11 showed that the combined therapies (cryotherapy→hyperthermia or hyperthermia→cryotherapy) were more effective on sarcoma 180 than hyperthermia or cryotherapy used alone(P<0.01).
