By the reactlon of (substituted silyl )methanethiols with 1-chloromethyl-2, 8, 9-tri-oxa- 5-aza-1-silabicyclo [3. 3, 3] undecane, eleven novel organosilicon compounds were syn-thesized. Their structures were confirmed...By the reactlon of (substituted silyl )methanethiols with 1-chloromethyl-2, 8, 9-tri-oxa- 5-aza-1-silabicyclo [3. 3, 3] undecane, eleven novel organosilicon compounds were syn-thesized. Their structures were confirmed by 1H NMR, MS and elementary analysis. A rare rearrangement breakdown pattern was found ln their mass spectra. Preliminary bioassay re-sults showed these compounds have some antitumor activity.展开更多
文摘By the reactlon of (substituted silyl )methanethiols with 1-chloromethyl-2, 8, 9-tri-oxa- 5-aza-1-silabicyclo [3. 3, 3] undecane, eleven novel organosilicon compounds were syn-thesized. Their structures were confirmed by 1H NMR, MS and elementary analysis. A rare rearrangement breakdown pattern was found ln their mass spectra. Preliminary bioassay re-sults showed these compounds have some antitumor activity.
