扫描离子电导显微镜(scanning ion conductance microscopy,SICM)是一种非接触式的扫描探针显微技术(scanning probe microscopy,SPM),可以实现生物样品在近生理条件下的成像。随着技术发展,目前广泛应用于生物医学领域的SICM主要包括两...扫描离子电导显微镜(scanning ion conductance microscopy,SICM)是一种非接触式的扫描探针显微技术(scanning probe microscopy,SPM),可以实现生物样品在近生理条件下的成像。随着技术发展,目前广泛应用于生物医学领域的SICM主要包括两种:跳跃式离子电导显微技术(hopping probe ion conductance microscopy,HPICM)和外加压力模式的SICM。前者可以应用于软的、黏的、对外力或其它机械信号敏感的样品的高分辨成像;后者可以通过探针微管对样品局部施加外力刺激或化学、电学、光学或生物分子等信号,实现对样品动力学性质或相关生理过程局部的原位研究。此外,SICM技术具有良好的开放性,能够越来越多地与其它技术手段联用,极大地丰富了其在生物医学领域的应用,可用于疾病发病机理、药物作用以及临床诊断等的研究。但是,目前SICM时间分辨率较低,这制约了它在生物体系动力学行为方面的研究。展开更多
A novel design of a tunable terahertz switch and band-pass filter using liquid-crystal-filled photonic crystal waveguide is demonstrated. The effects of magnetic field on the photonic bandgaps and transmitting propert...A novel design of a tunable terahertz switch and band-pass filter using liquid-crystal-filled photonic crystal waveguide is demonstrated. The effects of magnetic field on the photonic bandgaps and transmitting properties of a THz wave are investigated by using the plane wave expansion method and finite difference time domain method. The efficient photonic bandgap tuning is predicted such that the two-dimensional liquid-crystal-filled photonie crystal waveguide can serve as a switch and continuously tunable band-pass filter with controlling of the magnetic field.展开更多
文摘扫描离子电导显微镜(scanning ion conductance microscopy,SICM)是一种非接触式的扫描探针显微技术(scanning probe microscopy,SPM),可以实现生物样品在近生理条件下的成像。随着技术发展,目前广泛应用于生物医学领域的SICM主要包括两种:跳跃式离子电导显微技术(hopping probe ion conductance microscopy,HPICM)和外加压力模式的SICM。前者可以应用于软的、黏的、对外力或其它机械信号敏感的样品的高分辨成像;后者可以通过探针微管对样品局部施加外力刺激或化学、电学、光学或生物分子等信号,实现对样品动力学性质或相关生理过程局部的原位研究。此外,SICM技术具有良好的开放性,能够越来越多地与其它技术手段联用,极大地丰富了其在生物医学领域的应用,可用于疾病发病机理、药物作用以及临床诊断等的研究。但是,目前SICM时间分辨率较低,这制约了它在生物体系动力学行为方面的研究。
基金Supported by the National Basic Research Programme of China under Grant No 2007CB310403, the Nation Natural Science Foundation of China under Grant No 60772105 and 10704043, and the Key Programme of the Applied Basic Research of Tianjin under Grant No 7JCZDJC05500.
文摘A novel design of a tunable terahertz switch and band-pass filter using liquid-crystal-filled photonic crystal waveguide is demonstrated. The effects of magnetic field on the photonic bandgaps and transmitting properties of a THz wave are investigated by using the plane wave expansion method and finite difference time domain method. The efficient photonic bandgap tuning is predicted such that the two-dimensional liquid-crystal-filled photonie crystal waveguide can serve as a switch and continuously tunable band-pass filter with controlling of the magnetic field.
