1,2-Bis(4-hydroxy-3-methoxyphenyl)ethane,a by-product formed from synthesis reaction of vanillyl nonanoate,is separated by silica-gel column chromatography and characterized by 1HNMR,13CNMR and MS.
In this fig,natural capsinoids was synthesised from capsaicinoids by lipase-catalysis in acetone.The optimal reaction conditions as follows:50mmol vanillyl alcohol and 75mmol methyl nonanoate in 1 mL of acetone contai...In this fig,natural capsinoids was synthesised from capsaicinoids by lipase-catalysis in acetone.The optimal reaction conditions as follows:50mmol vanillyl alcohol and 75mmol methyl nonanoate in 1 mL of acetone containing 0.1%～0.3% of water(V/V) in the presence of 20 mg lipase.Under the conditions,at 30℃,more than 60% of yield was achived after 9 h.The corresponding fatty acid methyl ester of capsaicinoids was obtained by menthanolysis of nature capsaicin in HCl methanol and then the capsinoids was gained by the lipase-catalyzed esterfication of vanillyl alcohol with corresponding fatty acid methyl ester in acetone.The products was purified by silica gel column chromatography and characterized including capsiate,dihydrocapsiate and nordihydrocapsiate in the compound by1HNMR and MS.展开更多
文摘1,2-Bis(4-hydroxy-3-methoxyphenyl)ethane,a by-product formed from synthesis reaction of vanillyl nonanoate,is separated by silica-gel column chromatography and characterized by 1HNMR,13CNMR and MS.
文摘In this fig,natural capsinoids was synthesised from capsaicinoids by lipase-catalysis in acetone.The optimal reaction conditions as follows:50mmol vanillyl alcohol and 75mmol methyl nonanoate in 1 mL of acetone containing 0.1%～0.3% of water(V/V) in the presence of 20 mg lipase.Under the conditions,at 30℃,more than 60% of yield was achived after 9 h.The corresponding fatty acid methyl ester of capsaicinoids was obtained by menthanolysis of nature capsaicin in HCl methanol and then the capsinoids was gained by the lipase-catalyzed esterfication of vanillyl alcohol with corresponding fatty acid methyl ester in acetone.The products was purified by silica gel column chromatography and characterized including capsiate,dihydrocapsiate and nordihydrocapsiate in the compound by1HNMR and MS.
