Thifensulfuron was synthesized in two steps by reacting bis(trichloromethyl)carbonate(BTC) as a phosgene substitute with 2 methoxycarbonyl 3 aminosulfonylthiophene(AST) to give an intermediate sulfonylisocynate, which...Thifensulfuron was synthesized in two steps by reacting bis(trichloromethyl)carbonate(BTC) as a phosgene substitute with 2 methoxycarbonyl 3 aminosulfonylthiophene(AST) to give an intermediate sulfonylisocynate, which reacted with 2 amino 4 methoxy 6 methyl 1,3,5 triazine to give thifensulfuron. The optimum reaction conditions were n (AST)∶ n (BTC)=1∶0 56, reaction temperature 120～130 ℃ and reaction time (11±0 5) h. The purity of thifensulfuron obtained was 96 5%(HPLC) in overall yield 93%.展开更多
文摘Thifensulfuron was synthesized in two steps by reacting bis(trichloromethyl)carbonate(BTC) as a phosgene substitute with 2 methoxycarbonyl 3 aminosulfonylthiophene(AST) to give an intermediate sulfonylisocynate, which reacted with 2 amino 4 methoxy 6 methyl 1,3,5 triazine to give thifensulfuron. The optimum reaction conditions were n (AST)∶ n (BTC)=1∶0 56, reaction temperature 120～130 ℃ and reaction time (11±0 5) h. The purity of thifensulfuron obtained was 96 5%(HPLC) in overall yield 93%.
