{4-[4-p-nitrobenzoyl(thiophenyl) phenyl]} phenyl iodonium hexafluorophosphate(Ⅳ) is synthesized from iodobenzene,p-nitro-benzoic acid and diphenyl sulfide through Friedel-Crafts acylation、substitution reaction and m...{4-[4-p-nitrobenzoyl(thiophenyl) phenyl]} phenyl iodonium hexafluorophosphate(Ⅳ) is synthesized from iodobenzene,p-nitro-benzoic acid and diphenyl sulfide through Friedel-Crafts acylation、substitution reaction and metathesis.It’s structure is identified by UV,1HNMR,MS and IR.The photoinitiability of product is tested.展开更多
以5-溴水杨醛、4-氯苄氯为原料,通过消去、还原及溴化合成了4-溴-2-溴甲基-1-((4-溴苄基)氧)苯(3),以哌啶-4-酮合成了N-烯丙基-N-(4-哌啶基)对氯苯甲酰胺(7),通过(3)、(7)合成了一种新的非肽类小分子化合物CCR5拮抗剂N-烯丙基-N-(1-(5-...以5-溴水杨醛、4-氯苄氯为原料,通过消去、还原及溴化合成了4-溴-2-溴甲基-1-((4-溴苄基)氧)苯(3),以哌啶-4-酮合成了N-烯丙基-N-(4-哌啶基)对氯苯甲酰胺(7),通过(3)、(7)合成了一种新的非肽类小分子化合物CCR5拮抗剂N-烯丙基-N-(1-(5-溴-2-((4-氯苄基)氧基)苄基)-4-哌啶基)-4-氯苯甲酰胺(8),并对该产物进行了1 H NMR、13C NMR及MS表征。展开更多
文摘{4-[4-p-nitrobenzoyl(thiophenyl) phenyl]} phenyl iodonium hexafluorophosphate(Ⅳ) is synthesized from iodobenzene,p-nitro-benzoic acid and diphenyl sulfide through Friedel-Crafts acylation、substitution reaction and metathesis.It’s structure is identified by UV,1HNMR,MS and IR.The photoinitiability of product is tested.
文摘以5-溴水杨醛、4-氯苄氯为原料,通过消去、还原及溴化合成了4-溴-2-溴甲基-1-((4-溴苄基)氧)苯(3),以哌啶-4-酮合成了N-烯丙基-N-(4-哌啶基)对氯苯甲酰胺(7),通过(3)、(7)合成了一种新的非肽类小分子化合物CCR5拮抗剂N-烯丙基-N-(1-(5-溴-2-((4-氯苄基)氧基)苄基)-4-哌啶基)-4-氯苯甲酰胺(8),并对该产物进行了1 H NMR、13C NMR及MS表征。
