A fully three-dimensional Monte Carlo model for simulation of sculptured thin-film growth is presented. After explaining the model, the simulation results are compared with the corresponding experiments, and encouragi...A fully three-dimensional Monte Carlo model for simulation of sculptured thin-film growth is presented. After explaining the model, the simulation results are compared with the corresponding experiments, and encouraging consistency is proven. The morphology of sculptured thin films is then compared on periodical patterned and bare substrates. It is shown that there are more uniform structures and hence possible better optical properties by fabricating on patterned substrates. Finally, with the aid of computer simulation, we examine the sell-shadowing effect and our theoretical analysis of simulated morphology data deals with the accuracy of this model.展开更多
We demonstrate that thin films with micro/nanometre controllable morphology can be fabricated by the glancing angle deposition （GLAD） technique which is a physical vapour deposition technique. In this technique, the...We demonstrate that thin films with micro/nanometre controllable morphology can be fabricated by the glancing angle deposition （GLAD） technique which is a physical vapour deposition technique. In this technique, there are parameters which determine the morphology of the thin films： the incident angle, ratio of the deposition rate with respect to the substrate rotation rate, nature of the material being deposited, etc. We fabricate the morphology of column, pillar, helices, zigzag and study the parameters which determine morphology by given some examples of SEM.展开更多
胃癌是我国的主要恶性肿瘤之一,其发病率及死亡率在恶性肿瘤中居于首位,严重影响人民的身体健康。近年来,虽然对胃癌的基础理论和临床作了大量的研究,但对胃癌的病因、生物学行为仍处在初步探索阶段,对早期胃癌的诊断还缺少客观化定量指...胃癌是我国的主要恶性肿瘤之一,其发病率及死亡率在恶性肿瘤中居于首位,严重影响人民的身体健康。近年来,虽然对胃癌的基础理论和临床作了大量的研究,但对胃癌的病因、生物学行为仍处在初步探索阶段,对早期胃癌的诊断还缺少客观化定量指标,治疗方法更是匮乏。因此,迫切需要对胃癌作更深入的研究。染色体在数量和结构上的畸变,是公认的一种癌细胞特征。DNA 是染色体的主要物质基础。正常胃粘膜细胞 DNA 含量较恒定,其倍体类型主要表现为二倍体。但由正常细胞经过转化细胞,直至变为癌细胞时。展开更多
Measurement of DNA content and nuclear area by microspectrophotometry was performed in gastric carcinogenesis of three adult wolfdogs induced by N-Ethyl-N’-Nitro-N-Nitrosoguanidine (ENNG) . The mean values and standa...Measurement of DNA content and nuclear area by microspectrophotometry was performed in gastric carcinogenesis of three adult wolfdogs induced by N-Ethyl-N’-Nitro-N-Nitrosoguanidine (ENNG) . The mean values and standard deviations of nuclear DNA and the lesions in the area of different groups were as follows: normal gastric mucosa 10.03±2.30 (arbitrary unit, AU) and 28.76±5.85 (urn2) , atrophic gastritis 12.04 ±3.34 AU and 28.69±8.02μm^2; mild dysplasia 13.52±3.73 AU and 28.23±8.12μm^2; moderate dysplasia 20.88±4.57 AU and 47.58± 10.74μm^2; severe dysplasia 24.01±4.48 AU and 56.64±12.53μm^2; well-differentiated adenocarcinoma 33.07±9.38 AU and 72.99±15.57μm^2, respectively. The nuclear DNA content and nuclear area showed a significant statistical difference between normal gastric mucosa and gastric carcinoma (P【0.01) . The nuclear area of gastric carcinoma increased with DNA content (r =0.73, P【0.01) , and the distribution patterns of DNA content in the histogram showed that diploidy was decreased and polyploidy was increased in cancer. These findings indicated that DNA ploidy patterns and nuclear area could be a useful index in differentiated carcinoma and precancerous lesions.展开更多
文摘A fully three-dimensional Monte Carlo model for simulation of sculptured thin-film growth is presented. After explaining the model, the simulation results are compared with the corresponding experiments, and encouraging consistency is proven. The morphology of sculptured thin films is then compared on periodical patterned and bare substrates. It is shown that there are more uniform structures and hence possible better optical properties by fabricating on patterned substrates. Finally, with the aid of computer simulation, we examine the sell-shadowing effect and our theoretical analysis of simulated morphology data deals with the accuracy of this model.
文摘We demonstrate that thin films with micro/nanometre controllable morphology can be fabricated by the glancing angle deposition （GLAD） technique which is a physical vapour deposition technique. In this technique, there are parameters which determine the morphology of the thin films： the incident angle, ratio of the deposition rate with respect to the substrate rotation rate, nature of the material being deposited, etc. We fabricate the morphology of column, pillar, helices, zigzag and study the parameters which determine morphology by given some examples of SEM.
文摘胃癌是我国的主要恶性肿瘤之一,其发病率及死亡率在恶性肿瘤中居于首位,严重影响人民的身体健康。近年来,虽然对胃癌的基础理论和临床作了大量的研究,但对胃癌的病因、生物学行为仍处在初步探索阶段,对早期胃癌的诊断还缺少客观化定量指标,治疗方法更是匮乏。因此,迫切需要对胃癌作更深入的研究。染色体在数量和结构上的畸变,是公认的一种癌细胞特征。DNA 是染色体的主要物质基础。正常胃粘膜细胞 DNA 含量较恒定,其倍体类型主要表现为二倍体。但由正常细胞经过转化细胞,直至变为癌细胞时。
文摘Measurement of DNA content and nuclear area by microspectrophotometry was performed in gastric carcinogenesis of three adult wolfdogs induced by N-Ethyl-N’-Nitro-N-Nitrosoguanidine (ENNG) . The mean values and standard deviations of nuclear DNA and the lesions in the area of different groups were as follows: normal gastric mucosa 10.03±2.30 (arbitrary unit, AU) and 28.76±5.85 (urn2) , atrophic gastritis 12.04 ±3.34 AU and 28.69±8.02μm^2; mild dysplasia 13.52±3.73 AU and 28.23±8.12μm^2; moderate dysplasia 20.88±4.57 AU and 47.58± 10.74μm^2; severe dysplasia 24.01±4.48 AU and 56.64±12.53μm^2; well-differentiated adenocarcinoma 33.07±9.38 AU and 72.99±15.57μm^2, respectively. The nuclear DNA content and nuclear area showed a significant statistical difference between normal gastric mucosa and gastric carcinoma (P【0.01) . The nuclear area of gastric carcinoma increased with DNA content (r =0.73, P【0.01) , and the distribution patterns of DNA content in the histogram showed that diploidy was decreased and polyploidy was increased in cancer. These findings indicated that DNA ploidy patterns and nuclear area could be a useful index in differentiated carcinoma and precancerous lesions.
