In the present experiment,fructose-1,6-diphosphate（FDP）and captopril（Cap）wereadded to the cold potassium cardioplegia solution and the levels of malondialdehyde（MDA）,cre-atine phosphokinase MB（CPK-MB）,thrombox...In the present experiment,fructose-1,6-diphosphate（FDP）and captopril（Cap）wereadded to the cold potassium cardioplegia solution and the levels of malondialdehyde（MDA）,cre-atine phosphokinase MB（CPK-MB）,thromboxane B（TXB<sub>2</sub>）and 6-keto-PGF<sub>1α</sub> in plasma weremeasured during open-heart surgery.Quantitative study of myocardial ultrastructure and obser-vation of cardiac resuscitation were also undertaken.The findings suggested that FDP,especiallywhen combined with Cap could significantly strengthen the protective effects of cold potassiumcardioplegia solution on ischemic myocardium.展开更多
Nine cases of congenital subaortic stenosis (SAS) associated with ventricular septal defect(VSD)were reported. The age ranged from 6 to 14 years. Under extracorporeal circulation, excision of the subaortic septum was ...Nine cases of congenital subaortic stenosis (SAS) associated with ventricular septal defect(VSD)were reported. The age ranged from 6 to 14 years. Under extracorporeal circulation, excision of the subaortic septum was performed in 8 cases, an extracardiac valve conduit from apex of left ventricle to aorta was established in another patient with tunnel-type of SAS. The VSD was repaired with patch in 7 cases. sutured in other 2. The operation was successful. The precardiac murmurs disappeared postoperatively and the symptoms relieved remarkably.Following up the patients for 3 to 97 months , the curative effect was satisfactory. The pathoanatomic characters of the congenital cardiac malformations of SAS associated with VSD were analysed, its diagnosis and surgical treatment were discussed briefly.展开更多
基金The project was supported by the National Natural Science Foundation of China No.3880772
文摘In the present experiment,fructose-1,6-diphosphate（FDP）and captopril（Cap）wereadded to the cold potassium cardioplegia solution and the levels of malondialdehyde（MDA）,cre-atine phosphokinase MB（CPK-MB）,thromboxane B（TXB<sub>2</sub>）and 6-keto-PGF<sub>1α</sub> in plasma weremeasured during open-heart surgery.Quantitative study of myocardial ultrastructure and obser-vation of cardiac resuscitation were also undertaken.The findings suggested that FDP,especiallywhen combined with Cap could significantly strengthen the protective effects of cold potassiumcardioplegia solution on ischemic myocardium.
文摘Nine cases of congenital subaortic stenosis (SAS) associated with ventricular septal defect(VSD)were reported. The age ranged from 6 to 14 years. Under extracorporeal circulation, excision of the subaortic septum was performed in 8 cases, an extracardiac valve conduit from apex of left ventricle to aorta was established in another patient with tunnel-type of SAS. The VSD was repaired with patch in 7 cases. sutured in other 2. The operation was successful. The precardiac murmurs disappeared postoperatively and the symptoms relieved remarkably.Following up the patients for 3 to 97 months , the curative effect was satisfactory. The pathoanatomic characters of the congenital cardiac malformations of SAS associated with VSD were analysed, its diagnosis and surgical treatment were discussed briefly.
