Eight compounds are isolated from the ferment liquid of mangrove fungus(No.zzf33) by silica gel column chromatography.Their structures are determined to be ramlusin(1),monodictyxanthone(2),8-hydroxy-6-methyl-9-oxo-9H-...Eight compounds are isolated from the ferment liquid of mangrove fungus(No.zzf33) by silica gel column chromatography.Their structures are determined to be ramlusin(1),monodictyxanthone(2),8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester(3),(E)-dec-2-enedioic acid(4),succinic acid(5),urail(6),thymine(7) and nonacosanoic acid(8) on the basis of comprehensive spectroscopic analysis and chemical method.Compounds 1-3 are isolated from Penicillium sp.for the first time.Compound 8 is first found in marine fungus.In the primary bioassay,compound 2 and 3 exhibit high inhibition to hep2 and hepG2 cells lines.展开更多
文摘Eight compounds are isolated from the ferment liquid of mangrove fungus(No.zzf33) by silica gel column chromatography.Their structures are determined to be ramlusin(1),monodictyxanthone(2),8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester(3),(E)-dec-2-enedioic acid(4),succinic acid(5),urail(6),thymine(7) and nonacosanoic acid(8) on the basis of comprehensive spectroscopic analysis and chemical method.Compounds 1-3 are isolated from Penicillium sp.for the first time.Compound 8 is first found in marine fungus.In the primary bioassay,compound 2 and 3 exhibit high inhibition to hep2 and hepG2 cells lines.
