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J005A电磁波屏蔽织物对电磁脉冲辐照后小鼠血脑屏障的影响 被引量:1
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作者 张李燕 郭国祯 +1 位作者 郭鹞 任东青 《辐射研究与辐射工艺学报》 CAS CSCD 北大核心 2005年第2期99-100,共2页
With wide applications of electromagnetic instruments and equipments in medical treatment, scientific re- search and national defense, and daily life items of computers, mobile telephones, and microwave ovens etc, ele... With wide applications of electromagnetic instruments and equipments in medical treatment, scientific re- search and national defense, and daily life items of computers, mobile telephones, and microwave ovens etc, elec- tromagnetic radiations have brought us great benefit. However, there are potential damages with electromagnetic radiations,e.g. the electromagnetic pulse (EMP), which is not ionizing radiation but can cause vibration of atoms or molecules and alter electron energy levels. It has been reported that EMP could decrease the learning and recol- lection ability of mice and rats through inducing metabolic disorder of neurotransmitter in mice brain and affect the brain wave of anesthetized rats. EMP also has some effect on immune, procreation and endocrine system of mice. The integrity of the blood-brain barrier (BBB) was detected in order to observe the effects of J005A electro- magnetic wave shielding textile (JEWST) on bio-effects of EMP. 48 BALB/c male mice were randomly divided into exposure groups and JEWST protection groups (n=6). EMP was generated from a bounded-wave simulator and transmitted into a GTEM cell in which the mice were exposed. The field intensity was 0, 100, 200 and 400 kV m-1, respectively. The integrity of the BBB was determined by a quantitative measurement of Evans blue (EB) dye. The quantity of penetrated EB in brains of the mice increased obviously after exposure to 100, 200and 400 kV m-1 EMP, compared with the control groups (p<0.0 1). In JEWST prevention groups, the quantity of penetrated EB was significantly decreased after exposure compared with the exposure groups. EMPs of 100, 200 and 400 kV m-1 could increase the permeability of BBB in mice. The J005A electromagnetic wave shieldlng textile may prevent BBB from EMP induced BBB injury in mice. 展开更多
关键词 电磁脉冲 J005A电磁波屏蔽织物 血脑屏障
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电离辐射对小鼠小肠和结肠细胞凋亡的影响 被引量:9
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作者 丁桂荣 郭国祯 +3 位作者 田芙蓉 王晋 张李燕 郭鹞 《辐射研究与辐射工艺学报》 EI CAS CSCD 北大核心 2000年第1期63-67,共5页
观察不同剂量r射线照射对小鼠小肠和结肠细胞凋亡水平的影响。60Cor射线全 身照射 BALB/c 小鼠;剂量分别为 1、 6、 12Gy,于照射后 24h内分批取材,常规石蜡包埋, HE染色, Olympus显微镜下观察辐射... 观察不同剂量r射线照射对小鼠小肠和结肠细胞凋亡水平的影响。60Cor射线全 身照射 BALB/c 小鼠;剂量分别为 1、 6、 12Gy,于照射后 24h内分批取材,常规石蜡包埋, HE染色, Olympus显微镜下观察辐射诱导小肠和结肠细胞凋亡的情况。结果表明:正常小鼠小 肠细胞有自发的凋亡现象,平均每个隐窝的凋亡细胞数为0.038±0.059个,结肠在正常情况下没 有细胞凋亡发生;不同剂量r射线照射后小肠隐窝细胞凋亡数目明显增加(p <0.05),其中 1Gy 照射组凋亡峰在照射后 12h明显, 6Gy和 12Gy组分别在照射后 24h和 6h凋亡细胞最多。结 肠未见或偶见凋亡细胞;各照射剂量组及照射后不同时间(照射后 6、 12、 24h)组小肠隐窝细 胞凋亡数较相应结肠组显著增加(p<0.05)。说明在电离辐射的情况下,小肠较结肠能更有效的 清除辐射损伤的细胞,而后者在体内的蓄积可能与以后的肿瘤发生有关。 展开更多
关键词 辐射 小肠 结肠 细胞凋亡 小鼠 肿瘤
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两煤制天然气项目在新疆伊犁开工 被引量:1
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作者 张李燕 《煤炭工程》 北大核心 2009年第12期92-92,共1页
关键词 天然气项目 新疆伊犁 伊犁哈萨克自治州 山东新汶矿业集团 合作开发 电力集团 总投资
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