A new compound was synthesized with 1,2,3 trimethoxybenzene as the starting material, followed by acylation of Friedel Crafts, bromination reaction, the nucleophilic N substitution of imidazole . For 2 bromo 1 (2,3,4 ...A new compound was synthesized with 1,2,3 trimethoxybenzene as the starting material, followed by acylation of Friedel Crafts, bromination reaction, the nucleophilic N substitution of imidazole . For 2 bromo 1 (2,3,4 trimethoxyphenyl)ethanone in DMF,2 (1H imidazol 1 yl) 1 (2,3,4 trimethoxyphenyl) ethanone was obtained in yield of 62 7%. It was obtained that the best reaction condition which the molar ratio of bromo compound to imidazole will be 1∶5 and the reaction time will be 8 h under low temperature or room temperature. The structure of the product was confirmed by elemental analysis, 1H NMR and IR spectrum analysis.展开更多
The components extracted by petroleum ether from a Chinese herb - Rabdosina Serra(Maxim.) Hara were separated and detectedby GAS CHROMATOGRAPH ELECTRON IONIZATION DETECTOR. Their structures were searched and identifie...The components extracted by petroleum ether from a Chinese herb - Rabdosina Serra(Maxim.) Hara were separated and detectedby GAS CHROMATOGRAPH ELECTRON IONIZATION DETECTOR. Their structures were searched and identified by HPNBS75K data base and proved that there are fifteen known compounds in this herb.展开更多
The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halog...The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.展开更多
A facile and efficient diastereoselective synthesis of 7 epi γ eudesmol starting from(-) dihydrocarvone has been carried out in 5 steps at the first time. [WT5HZ]
文摘A new compound was synthesized with 1,2,3 trimethoxybenzene as the starting material, followed by acylation of Friedel Crafts, bromination reaction, the nucleophilic N substitution of imidazole . For 2 bromo 1 (2,3,4 trimethoxyphenyl)ethanone in DMF,2 (1H imidazol 1 yl) 1 (2,3,4 trimethoxyphenyl) ethanone was obtained in yield of 62 7%. It was obtained that the best reaction condition which the molar ratio of bromo compound to imidazole will be 1∶5 and the reaction time will be 8 h under low temperature or room temperature. The structure of the product was confirmed by elemental analysis, 1H NMR and IR spectrum analysis.
文摘The components extracted by petroleum ether from a Chinese herb - Rabdosina Serra(Maxim.) Hara were separated and detectedby GAS CHROMATOGRAPH ELECTRON IONIZATION DETECTOR. Their structures were searched and identified by HPNBS75K data base and proved that there are fifteen known compounds in this herb.
文摘The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.
文摘A facile and efficient diastereoselective synthesis of 7 epi γ eudesmol starting from(-) dihydrocarvone has been carried out in 5 steps at the first time. [WT5HZ]
