目的:系统评价前入路与后入路两种不同手术治疗胸腰椎爆裂性骨折的疗效与安全性。方法:通过检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE等数据库,全面收集前入路与后入路手术治疗腰椎滑脱症的随机、半...目的:系统评价前入路与后入路两种不同手术治疗胸腰椎爆裂性骨折的疗效与安全性。方法:通过检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE等数据库,全面收集前入路与后入路手术治疗腰椎滑脱症的随机、半随机对照试验(RCT,quasi-RCT)结果,并用Rev Man 5.0.2软件进行Meta分析。结果:纳入7个试验共331例患者。前入路和后入路手术治疗胸腰椎爆裂性骨折的侵占程度、Cobb角、Frankel分级及重返工作岗位的患者数比较,差异无统计学意义[MD=-8.02,95%CI(-17.33,0.92),P=0.08;MD=-0.06,95%CI(-0.62,0.51),P=0.84;RD=0.06,95%CI(-0.07,0.19),P=0.38;RD=-0.02,95%CI(-0.16,0.13),P=0.80]。前入路组与后入路组治疗胸腰椎爆裂性骨折的术中出血量、手术时间及手术费用比较,差异有统计学意义[MD=310.67,95%CI(26.38,594.96),P=0.03;MD=17.17,95%CI(5.78,28.57),P=0.003;MD=15.53,95%CI(6.72,24.34),P=0.0006];但两组间的其他不良反应发生率差异无统计学意义。结论:后入路手术治疗胸腰椎爆裂性骨折比前入路手术更有效,能减少术中出血量、手术时间及手术费用。展开更多
目的:系统评价后外侧植骨融合(PLF)与后路椎体间融合(PLIF)两种术式治疗腰椎滑脱症的疗效。方法:计算机检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI;手工检索JBJS,Spine,Euro Spine及中国脊...目的:系统评价后外侧植骨融合(PLF)与后路椎体间融合(PLIF)两种术式治疗腰椎滑脱症的疗效。方法:计算机检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI;手工检索JBJS,Spine,Euro Spine及中国脊柱脊髓杂志、中华骨科学杂志等相关杂志;全面收集PLF与PLIF手术治疗腰椎滑脱症的RCT或非RCT,用Rev Man 5.0.2软件进行Meta分析。结果:纳入11项临床研究,Meta分析结果表明:PLIF组治疗腰椎滑脱症术后总体临床疗效和术后骨性融合率显著优于PLF组[OR=0.50,95%CI(0.28,0.88),P=0.02;OR=0.32,95%CI(0.18,0.57),P<0.000 1]。PLIF组治疗腰椎滑脱症背部疼痛量、术后并发症发生率以及再次手术率显著低于PLF组[MD=0.76,95%CI(0.48,1.04),P<0.00001;OR=2.41,95%CI(1.09,5.34),P=20.03;OR=6.06,95%CI(2.00,18.33),P=0.001]。术中手术出血量和手术时间两组比较,差异无统计学意义[MD=-55.25,95%CI(-427.84,317.34),P=0.77;MD=-19.32,95%CI(-64.98,26.51),P=0.41]。结论:与PLF相比,PLF可显著提高临床疗效和骨性融合率,减少背部疼痛,降低并发症发生率和再次手术率,出血量及手术时间两者无差异。展开更多
目的:通过Meta分析比较益气补血法治疗肿瘤相关性贫血(非化疗相关)患者的有效性与安全性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI;全面收集益气补血法治疗肿瘤相关性贫血(非...目的:通过Meta分析比较益气补血法治疗肿瘤相关性贫血(非化疗相关)患者的有效性与安全性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI;全面收集益气补血法治疗肿瘤相关性贫血(非化疗相关)患者的临床随机对照试验,用Review Manager 5.0软件进行Meta分析。结果:最终纳入13项随机对照临床研究,共计1198例患者。Meta分析结果表明:益气补血法治疗组的血红蛋白水平显著高于对照组[MD=4.57,95%CI(1.38~7.76),P<0.0001,I 2=97%];益气补血法治疗组的总有效率显著高于对照组[RR=1.31,95%CI(1.18~1.46),P<0.0001,I 2=51%];益气补血法治疗组的不良反应发生率与对照组比较,差异无统计学意义[RR=0.54,95%CI(0.29~0.99),P=0.05,I 2=45%]。结论:益气补血法可有效治疗肿瘤相关性贫血(非化疗相关),可提高血红蛋白水平和临床总有效率,治疗效果优于促红细胞生成素(EPO)或铁剂,且不良反应少。展开更多
目的:通过Meta分析研究头孢洛林治疗儿童急性细菌感染性疾病的有效性与安全性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM和CNKI,全面收集头孢洛林治疗儿童急性细菌感染性疾病的临床...目的:通过Meta分析研究头孢洛林治疗儿童急性细菌感染性疾病的有效性与安全性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM和CNKI,全面收集头孢洛林治疗儿童急性细菌感染性疾病的临床随机对照试验,用Review manager 5.0软件进行Meta分析。结果:最终纳入3项随机对照临床研究,共计363例患者。Meta分析结果表明:在临床可评估患者中,头孢洛林组的临床治愈率与对照组相当,治疗结束后(EOT)临床治愈率为92.6%[OR=1.93,95%Cl(0.88~4.25),P=0.1,I 2=0%],随访期结束后(TOC)临床治愈率为90.9%[OR=1.36,95%CI(0.64~2.91),P=0.43,I 2=14%];头孢洛林组的临床治疗失败率与对照组相当,EOT临床治疗失败率为4.1%[OR=0.62,95%CI(0.22~1.76),P=0.37,I 2=0%],TOC临床治疗失败率为4.5%[OR=0.68,95%CI(0.24~1.91),P=0.46,I 2=0%];头孢洛林组治疗期间不良事件(TEAE)发生率与对照组相当[OR=0.81,95%CI(0.37~1.78),P=0.60,I 2=0%],且各种程度的TEAE发生率均与对照组相当;头孢洛林组的药物相关性TEAE发生率和药物相关性严重TEAE发生率均与对照组相当[OR=0.98,95%CI(0.53~1.83),P=0.96,I 2=0%和OR=1.16,95%CI(0.34~3.96),P=0.81,I 2=22%]。结论:头孢洛林治疗儿童急性细菌感染性疾病的临床疗效和安全性较好。展开更多
目的:通过Meta分析研究补充胶原蛋白对缓解骨性关节炎(OA)症状的有效性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI,全面收集补充胶原蛋白对缓解骨性关节炎症状有效性的临床随机...目的:通过Meta分析研究补充胶原蛋白对缓解骨性关节炎(OA)症状的有效性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI,全面收集补充胶原蛋白对缓解骨性关节炎症状有效性的临床随机对照试验,用Review Manager 5.0软件进行Meta分析。结果:最终纳入5项随机对照试验组,共计470例患者;补充胶原蛋白可有效降低骨性关节炎患者西安大略和麦克马斯特大学骨性关节炎(WOMAC)指数评分;亚组分析发现,补充胶原蛋白可有效降低骨性关节炎患者关节僵硬评分,而对疼痛和功能受限无显著缓解作用,差异无统计学意义;补充胶原蛋白可有效降低骨性关节炎患者视觉模拟法(VAS)评分。结论:补充胶原蛋白可有效缓解骨性关节炎患者的症状,降低WOMAC指数评分和VAS评分。展开更多
We report that using asymmetric lattice periods can enhance the quality factor of plasmonic surface lattice resonances(SLRs)in two-dimensional array of metal-insulator-metal nanopillars in asymmetric dielectric enviro...We report that using asymmetric lattice periods can enhance the quality factor of plasmonic surface lattice resonances(SLRs)in two-dimensional array of metal-insulator-metal nanopillars in asymmetric dielectric environment.Simulation results show that by adopting appropriate asymmetric lattice periods,the SLR quality factor can be enhanced by 24%compared with the scenario of symmetric periods.We find that the SLR quality factor is optimized when the resonance wavelength is closest to the Rayleigh cutoff wavelength.We also find that the SLRs effect is polarization sensitive in the proposed structure.We expect this work will advance the engineering of SLRs especially in asymmetric dielectric environments,and will promote their applications in sensing.展开更多
文摘目的:系统评价前入路与后入路两种不同手术治疗胸腰椎爆裂性骨折的疗效与安全性。方法:通过检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE等数据库,全面收集前入路与后入路手术治疗腰椎滑脱症的随机、半随机对照试验(RCT,quasi-RCT)结果,并用Rev Man 5.0.2软件进行Meta分析。结果:纳入7个试验共331例患者。前入路和后入路手术治疗胸腰椎爆裂性骨折的侵占程度、Cobb角、Frankel分级及重返工作岗位的患者数比较,差异无统计学意义[MD=-8.02,95%CI(-17.33,0.92),P=0.08;MD=-0.06,95%CI(-0.62,0.51),P=0.84;RD=0.06,95%CI(-0.07,0.19),P=0.38;RD=-0.02,95%CI(-0.16,0.13),P=0.80]。前入路组与后入路组治疗胸腰椎爆裂性骨折的术中出血量、手术时间及手术费用比较,差异有统计学意义[MD=310.67,95%CI(26.38,594.96),P=0.03;MD=17.17,95%CI(5.78,28.57),P=0.003;MD=15.53,95%CI(6.72,24.34),P=0.0006];但两组间的其他不良反应发生率差异无统计学意义。结论:后入路手术治疗胸腰椎爆裂性骨折比前入路手术更有效,能减少术中出血量、手术时间及手术费用。
文摘目的:系统评价后外侧植骨融合(PLF)与后路椎体间融合(PLIF)两种术式治疗腰椎滑脱症的疗效。方法:计算机检索Pub Med,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI;手工检索JBJS,Spine,Euro Spine及中国脊柱脊髓杂志、中华骨科学杂志等相关杂志;全面收集PLF与PLIF手术治疗腰椎滑脱症的RCT或非RCT,用Rev Man 5.0.2软件进行Meta分析。结果:纳入11项临床研究,Meta分析结果表明:PLIF组治疗腰椎滑脱症术后总体临床疗效和术后骨性融合率显著优于PLF组[OR=0.50,95%CI(0.28,0.88),P=0.02;OR=0.32,95%CI(0.18,0.57),P<0.000 1]。PLIF组治疗腰椎滑脱症背部疼痛量、术后并发症发生率以及再次手术率显著低于PLF组[MD=0.76,95%CI(0.48,1.04),P<0.00001;OR=2.41,95%CI(1.09,5.34),P=20.03;OR=6.06,95%CI(2.00,18.33),P=0.001]。术中手术出血量和手术时间两组比较,差异无统计学意义[MD=-55.25,95%CI(-427.84,317.34),P=0.77;MD=-19.32,95%CI(-64.98,26.51),P=0.41]。结论:与PLF相比,PLF可显著提高临床疗效和骨性融合率,减少背部疼痛,降低并发症发生率和再次手术率,出血量及手术时间两者无差异。
文摘目的:通过Meta分析研究补充胶原蛋白对缓解骨性关节炎(OA)症状的有效性。方法:计算机检索PubMed,EMBASE,Cochrane Central Register of Controlled Trials,MEDLINE,CBM,CNKI,全面收集补充胶原蛋白对缓解骨性关节炎症状有效性的临床随机对照试验,用Review Manager 5.0软件进行Meta分析。结果:最终纳入5项随机对照试验组,共计470例患者;补充胶原蛋白可有效降低骨性关节炎患者西安大略和麦克马斯特大学骨性关节炎(WOMAC)指数评分;亚组分析发现,补充胶原蛋白可有效降低骨性关节炎患者关节僵硬评分,而对疼痛和功能受限无显著缓解作用,差异无统计学意义;补充胶原蛋白可有效降低骨性关节炎患者视觉模拟法(VAS)评分。结论:补充胶原蛋白可有效缓解骨性关节炎患者的症状,降低WOMAC指数评分和VAS评分。
基金the State Key Laboratory of Advanced Optical Communication Systems and Networks,China(Grant No.2019GZKF2).
文摘We report that using asymmetric lattice periods can enhance the quality factor of plasmonic surface lattice resonances(SLRs)in two-dimensional array of metal-insulator-metal nanopillars in asymmetric dielectric environment.Simulation results show that by adopting appropriate asymmetric lattice periods,the SLR quality factor can be enhanced by 24%compared with the scenario of symmetric periods.We find that the SLR quality factor is optimized when the resonance wavelength is closest to the Rayleigh cutoff wavelength.We also find that the SLRs effect is polarization sensitive in the proposed structure.We expect this work will advance the engineering of SLRs especially in asymmetric dielectric environments,and will promote their applications in sensing.
