Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their struc...Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their structures and purities were determined via IR,1H NMR and elemental analysis.The seeded microspheres of polystyrene(about 3 μm) were prepared with dispersion polymerization,and monodisperse hollow chiral polymer microspheres were prepared with two-stage swelling procedure via copolymerization of styrene,divinyl benzene and the chiral monomers synthesized above.The average diameter of the microsphere was about 10 μm.The chiral polymer microspheres were used to be the stationary phase of HPLC.The molar ratio of(S)-α-ethyl hydroxy phenylbutyrate and(R)-α-ethylhydroxy phenylbutyrate were determined via chiral HPLC.The chromatography results showed that the chiral recognition was very higy when using chiral polymer microsphere,prepared by S-10-undecylenoyl(α-phenyl)ethylamide as chiral monomer,as chiral stationary phase of HPLC.展开更多
The title ligand(A) was synthesized through condensation of 2-pyridine aldehydeand L-methyl cysteine hydrochloride. The isomers of (A) were separated by column chromatography. The in-situ prepared catalyst from (A) wi...The title ligand(A) was synthesized through condensation of 2-pyridine aldehydeand L-methyl cysteine hydrochloride. The isomers of (A) were separated by column chromatography. The in-situ prepared catalyst from (A) with [Rh(COD)CI]2 (COD:cyclooctadiene) has been used to catalyze the asymmetric hydrosilylation of acetophenone. The resultsshowed that only the configuration of C4, but not that of C2 affected the optical yield andconfiguration of the products.展开更多
文摘Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their structures and purities were determined via IR,1H NMR and elemental analysis.The seeded microspheres of polystyrene(about 3 μm) were prepared with dispersion polymerization,and monodisperse hollow chiral polymer microspheres were prepared with two-stage swelling procedure via copolymerization of styrene,divinyl benzene and the chiral monomers synthesized above.The average diameter of the microsphere was about 10 μm.The chiral polymer microspheres were used to be the stationary phase of HPLC.The molar ratio of(S)-α-ethyl hydroxy phenylbutyrate and(R)-α-ethylhydroxy phenylbutyrate were determined via chiral HPLC.The chromatography results showed that the chiral recognition was very higy when using chiral polymer microsphere,prepared by S-10-undecylenoyl(α-phenyl)ethylamide as chiral monomer,as chiral stationary phase of HPLC.
文摘The title ligand(A) was synthesized through condensation of 2-pyridine aldehydeand L-methyl cysteine hydrochloride. The isomers of (A) were separated by column chromatography. The in-situ prepared catalyst from (A) with [Rh(COD)CI]2 (COD:cyclooctadiene) has been used to catalyze the asymmetric hydrosilylation of acetophenone. The resultsshowed that only the configuration of C4, but not that of C2 affected the optical yield andconfiguration of the products.
