Atmospheric pressure low-temperature plasma is a promising tool in biomedicine applications including blood coagulation,bacterial inactivation,sterilization,and cancer treatment,due to its high chemical activity and l...Atmospheric pressure low-temperature plasma is a promising tool in biomedicine applications including blood coagulation,bacterial inactivation,sterilization,and cancer treatment,due to its high chemical activity and limited thermal damage.It is of great importance to develop portable plasma sources that are safe to human touch and suitable for outdoor and household operation.In this work,a portable and rechargeable low-temperature plasma spark discharge device(130 mm×80 mm×35 mm,300 g)was designed.The discharge frequency and plume length were optimized by the selection of resistance,capacitance,electrode gap,and ground electrode aperture.Results show that the spark plasma plume is generated with a length of 12 mm and a frequency of 10 Hz at a capacitance of 0.33μF.resistance of 1 MΩ,electrode gap of 2 mm,and ground electrode aperture of 1.5 mm.Biological tests indicate that the plasma produced by this device contains abundant reactive species,which can be applied in plasma biomedicine,including daily sterilization and wound healing.展开更多
A stable and homogeneous well-aligned air microplasma device for application at atmospheric pressure is designed and its electrical and optical characteristics are investigated. Current-voltage measurements and intens...A stable and homogeneous well-aligned air microplasma device for application at atmospheric pressure is designed and its electrical and optical characteristics are investigated. Current-voltage measurements and intensified charge coupled device （ICCD） images show that the well-aligned air microplasma device is able to generate a large-area and homogeneous discharge at the applied voltages ranging from 12 kV to 14 kV, with a repetition frequency of 5 kHz, which is attributed to the diffusion effect of plasma on dielectric surface. Moreover, this well-aligned microplasma device may result in the uniform and large-area surface modification of heat-sensitive PET polymers without damage, such as optimization in hydrophobicity and biocompatibility. In the biomedical field, the utility of this well-aligned microplasma device is further testified. It proves to be very efficient for the large-area and uniform inactivation of E. coli cells with a density of 103/cm2 on LB agar plate culture medium, and inactivation efficiency can reach up to 99% for 2-min treatment.展开更多
In this work,a portable floating-electrode dielectric barrier discharge(FE-DBD)device is designed with a rechargeable battery as the power supply.The characteristics of the FE-DBD with a metal electrode and human hand...In this work,a portable floating-electrode dielectric barrier discharge(FE-DBD)device is designed with a rechargeable battery as the power supply.The characteristics of the FE-DBD with a metal electrode and human hand are studied and compared.The human contact safety is verified by calculating the current through the human body based on the equivalent circuit model.Escherichia coli inactivation experiments confirm the efficacy of the FE-DBD device in the envisaged applications.展开更多
基金supported by National Natural Science Foundation of China(Nos.51677083 and 51377075)Postgraduate Research and Practice Innovation Program of Jiangsu Province(SJCX18_0340)
文摘Atmospheric pressure low-temperature plasma is a promising tool in biomedicine applications including blood coagulation,bacterial inactivation,sterilization,and cancer treatment,due to its high chemical activity and limited thermal damage.It is of great importance to develop portable plasma sources that are safe to human touch and suitable for outdoor and household operation.In this work,a portable and rechargeable low-temperature plasma spark discharge device(130 mm×80 mm×35 mm,300 g)was designed.The discharge frequency and plume length were optimized by the selection of resistance,capacitance,electrode gap,and ground electrode aperture.Results show that the spark plasma plume is generated with a length of 12 mm and a frequency of 10 Hz at a capacitance of 0.33μF.resistance of 1 MΩ,electrode gap of 2 mm,and ground electrode aperture of 1.5 mm.Biological tests indicate that the plasma produced by this device contains abundant reactive species,which can be applied in plasma biomedicine,including daily sterilization and wound healing.
基金supported by the Natural Science Foundation of Fujian Province,China(Grant No.2014J01025)the National Natural Science Foundation of China(Grant No.11275261)+1 种基金the Natural Science Foundation of Guangdong Province,China(Grant No.2015A030313005)the Fund from the Fujian Provincia Key Laboratory for Plasma and Magnetic Resonance,China
文摘A stable and homogeneous well-aligned air microplasma device for application at atmospheric pressure is designed and its electrical and optical characteristics are investigated. Current-voltage measurements and intensified charge coupled device （ICCD） images show that the well-aligned air microplasma device is able to generate a large-area and homogeneous discharge at the applied voltages ranging from 12 kV to 14 kV, with a repetition frequency of 5 kHz, which is attributed to the diffusion effect of plasma on dielectric surface. Moreover, this well-aligned microplasma device may result in the uniform and large-area surface modification of heat-sensitive PET polymers without damage, such as optimization in hydrophobicity and biocompatibility. In the biomedical field, the utility of this well-aligned microplasma device is further testified. It proves to be very efficient for the large-area and uniform inactivation of E. coli cells with a density of 103/cm2 on LB agar plate culture medium, and inactivation efficiency can reach up to 99% for 2-min treatment.
基金supported by National Natural Science Foundation of China(Nos.51907088,51677019)。
文摘In this work,a portable floating-electrode dielectric barrier discharge(FE-DBD)device is designed with a rechargeable battery as the power supply.The characteristics of the FE-DBD with a metal electrode and human hand are studied and compared.The human contact safety is verified by calculating the current through the human body based on the equivalent circuit model.Escherichia coli inactivation experiments confirm the efficacy of the FE-DBD device in the envisaged applications.
