The rat vertebral and common carotid arteries were obstructed to cause bilateralhemispheric ischemia.Vasoactive intestinal peptide(VIP)in the rat cerebral cortex following 10~60min of ischemia was analysed by radioim...The rat vertebral and common carotid arteries were obstructed to cause bilateralhemispheric ischemia.Vasoactive intestinal peptide(VIP)in the rat cerebral cortex following 10~60min of ischemia was analysed by radioimmunoassay(RIA).The results showed that the levels ofVIP were significantly lower in the ischemic animals than controls(P【0.01).The distribution andmetabolism of VIP in the cerebral cortex and the probable mechanism during ischemia are dis-cussed.展开更多
文摘The rat vertebral and common carotid arteries were obstructed to cause bilateralhemispheric ischemia.Vasoactive intestinal peptide(VIP)in the rat cerebral cortex following 10~60min of ischemia was analysed by radioimmunoassay(RIA).The results showed that the levels ofVIP were significantly lower in the ischemic animals than controls(P【0.01).The distribution andmetabolism of VIP in the cerebral cortex and the probable mechanism during ischemia are dis-cussed.