近年来,无需复杂样品前处理、且在开放环境下实现离子化的常压敞开式离子化质谱技术(Ambientionization mass spectrometry,AI-MS)的研制与应用成为质谱学领域的前沿及备受关注的研究方向。该文综述了AI离子源的基本原理、特征与应用进...近年来,无需复杂样品前处理、且在开放环境下实现离子化的常压敞开式离子化质谱技术(Ambientionization mass spectrometry,AI-MS)的研制与应用成为质谱学领域的前沿及备受关注的研究方向。该文综述了AI离子源的基本原理、特征与应用进展,并结合笔者研制的空气动力辅助离子化(Air flow assisted ioniza-tion,AFAI)技术,介绍了气流辅助常压敞开式离子化技术的基本特点及其应用。展望了常压敞开式离子化技术的发展趋势。展开更多
In this paper, the mass spectrometry of three 4,20-double bonded 5/7/6 type taxoids and association of the fragmentation behavior with the hoes and positions of the substituents have been investigated by tandem mass s...In this paper, the mass spectrometry of three 4,20-double bonded 5/7/6 type taxoids and association of the fragmentation behavior with the hoes and positions of the substituents have been investigated by tandem mass spectromecy the results demonstrate that the loss of HOBz is the major mode of decomposition for [M+Na]+ ions of 1 and 2, while [M+H]+ ion of 3 mainly undergoes the decomposition reactions of eliminating one and two HZO molecules. After losses of all AcO and BiO groups and some OH groups, 1 and 2 form fragment ions with stable conjugated systems at ac 237, and 3 at m/z 253.展开更多
文摘In this paper, the mass spectrometry of three 4,20-double bonded 5/7/6 type taxoids and association of the fragmentation behavior with the hoes and positions of the substituents have been investigated by tandem mass spectromecy the results demonstrate that the loss of HOBz is the major mode of decomposition for [M+Na]+ ions of 1 and 2, while [M+H]+ ion of 3 mainly undergoes the decomposition reactions of eliminating one and two HZO molecules. After losses of all AcO and BiO groups and some OH groups, 1 and 2 form fragment ions with stable conjugated systems at ac 237, and 3 at m/z 253.
