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静脉麻醉药物与细胞焦亡的研究现状

Research Status of Intravenous Anesthetic Drugs and Cell Pyroptosis
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摘要 舒适医疗逐步被大众认可,无论是手术麻醉、术后镇痛治疗还是镇静镇痛检查,麻醉药物的应用必不可少。疾病、感染、器官低灌注、缺血再灌注等情况均会导致细胞焦亡,焦亡表现为一系列的炎性级联反应,对机体的伤害性显而易见。那么,静脉麻醉药物是导致焦亡产生的原因之一亦或是加剧细胞焦亡,还是可产生有益影响?本着这样的疑惑,对静脉麻醉药物与细胞焦亡相关的研究现状进行以下概括。 Comfort medical care has gradually been recognized by the public. Whether it is surgical anesthesia, postoperative analgesia treatment or sedation and analgesia examination, the application of anesthetic drugs is essential. Diseases, infections, organ hypoperfusion, ischemia and reperfusion can all lead to pyrolysis of cells. Pyrolysis is manifested as a series of inflammatory cascades, which are obviously harmful to the body. So, is intravenous anesthetic drugs one of the causes of pyroptosis or aggravate pyroptosis, or can they have beneficial effects? Based on this doubt, the current research status of intravenous anesthetic drugs and cell pyroptosis is summarized below.
作者 高李娜
出处 《临床医学进展》 2025年第8期570-576,共7页 Advances in Clinical Medicine

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