摘要
目的探讨高位硬膜外阻滞(TAE)对冠心病患者心率变异性的影响。方法选取2013年1月~2014年2月我院收治的冠心病患者62例,随机分为对照组和观察组,每组31例,其中对照组采取常规内科治疗,观察组在对照组基础上采取高位硬膜外阻滞治疗。观察比较两组患者的心率变异性情况。结果用药后,对照组患者的LF、HF以及LF/HF变化不明显(P>0.05),观察组患者的LF、HF以及LF/HF均较基础值明显下降(P<0.05)。结论 TAE可相对提高迷走神经张力、阻滞交管神经活性,使冠状血管扩张,改善心肌缺氧情况,从而起到治疗冠心病的作用。
Objective To investigate the effect of high thoracic epidural anesthesia (TEA) on heart rate variability in patients with coronary heart disease. Methods A total of 62 patients with coronary heart disease who were admitted to our hospital from January 2013 to February 2014 were randomized into control group and observation group, with 31 patients in each group. The patients in the control group were given conventional medical treatment, and those in the observation group were given high TEA in addition to the conventional medical treatment. Heart rate variability was observed and compared between the two groups. Results After medication, there were no significant changes in low frequency (LF), high frequency (HF), and LF/HF in the control group (P>0.05), while there were significant reductions in LF, HF, and LF/HF compared with baseline in the observation group (P<0.05). Conclusion TEA can relatively increase vagal tone, block sympathetic nerve activity, dilate the coronary artery, improve myocardial anoxia, and thus achieve the therapeutic effect for coronary heart disease.
出处
《心血管病防治知识（学术版）》
2016年第1期39-40,共2页
Prevention and Treatment of Cardiovascular Disease
关键词
高位硬膜外阻滞
冠心病
心率变异
High thoracic epidural anesthesia
Coronary heart disease
Heart rate variability
