摘要
目的:分析重症肺炎患者前降钙素(PCT)的变化,探讨其意义及对预后的影响。方法:收治重症肺炎患者47例,于入院后第1、3、5天及离开ICU前测定PCT值,根据预后将患者分为生存组和死亡组,比较两组患者PCT值变化、急性生理和慢性健康评分(APACHEⅡ评分)、中心静脉血氧饱和度(Scv O2)。结果:死亡组第1天PCT值、APACHE II评分高于生存组,Scv O2低于生存组,但差异均无统计学意义(P>0.05),死亡组和生存组第3、5天及离开ICU前PCT值、APACHEⅡ评分高于生存组,Scv O2低于生存组,差异均有统计学意义(P<0.05),且死亡组PCT值呈进行性上升趋势,生存组呈下降趋势。结论:重症肺炎患者PCT水平与病情严重性有明显相关性,PCT水平对判断其病程发展、预后有一定价值。
Objective:To analyze the procalcitonin(PCT) changes of patients with severe pneumonia,to explore its significance and influence on prognosis.Methods:47 patients with severe pneumonia were selected.The PCT value was measured at the first day,the third day,the fifth day after admission and before leaving ICU.According to prognosis,patients were divided into the survival group and the death group.We compared the changes of PCT value,acute physiology and chronic health score(APACHE score),central venous oxygen saturation(Scv O2) of the two groups.Results:In death group,PCT value,APACHE Ⅱ score at the third day were higher than the survival group,and Scv O2 was less than the survival group,with no significant difference(P>0.05).In the death group and the survival group,the value of PCT and APACHE Ⅱ score at the third day,the fifth day and before leaving ICU were higher than the survival group,and Scv O2 was less than the survival group;the difference was statistically significant(P<0.05).In death group,PCT value was of a rising trend,and the survival group was a downward trend.Conclusion:In patients with severe pneumonia,PCT levels had significant correlation with disease severity,and PCT level was helpful for predicting disease development and prognosis.
出处
《中国社区医师》
2015年第4期109-110,共2页
Chinese Community Doctors
关键词
重症肺炎
前降钙素
预后
Severe pneumonia
Procalcitonin
Prognosis
