摘要
我国是胃癌高发国家,开展大规模人群筛查对实现胃癌的早期诊疗具有重要意义。当前的实践经验表明,筛查方法和模式的选择与目标人群依从性、筛查覆盖率及病变检出率密切相关。目前成熟的胃癌筛查方法包括血清学检查、胃镜检查、液体活检等,筛查模式涵盖了以胃镜普查为主的“一步法策略”和血清学检查与胃镜检查组合的“序贯式策略”。本文回顾分析当前主要胃癌筛查方法和模式的特点及性能,并借鉴其他癌种筛查方法的优势提出胃癌筛查的潜在策略,以期为胃癌筛查的可行路径提供参考,进一步助力我国胃癌筛查规范化建设。
As China is a country with high incidence of gastric cancer,it is of great signi ficance to actively carry out mass screening at the population level for early diagnosis and treatment of gastric cancer.Current practical experience shows that the selection of screening methods and patterns is closely related to the compliance of the target population,screening coverage and lesion detection rate.Currently,mature gastric cancer screening methods include serologic examination,gastroscopy,liquid biopsy,etc.,while screening patterns include“one-step strategy”based on gastroscopy and“sequential strategy”combining serologic examination and gastroscopy.The purpose of this paper is to review the current mainstream status of gastric cancer screening methods and patterns,and to draw on the potential advantages of other cancer screening methods,with a view to providing reference for the exploration of feasible pathways for gastric cancer screening,and further contributing to the standardization of gastric cancer screening in China.
作者
仇祎凡
周显祝
李兆申
杜奕奇
QIU Yifan;ZHOU Xianzhu;LI Zhaoshen;DU Yiqi(Department of Gastroenterology,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China)
出处
《海军军医大学学报》
2025年第10期1336-1343,共8页
Academic Journal of Naval Medical University
基金
“四大慢病”国家科技重大专项(2025ZD05453004)
国家自然科学基金(82470594,82504509)
上海市加强公共卫生体系建设三年行动计划(2023-2025年)重点学科建设项目(GWVI-11.1-21).
关键词
胃肿瘤
筛查方法
筛查模式
序贯式筛查
gastric neoplasms
screening methods
screening patterns
sequential screening
作者简介
仇祎凡.E-mail:qiuyifan123@outlook.com;通信作者:杜奕奇.E-mail:duyiqi@hotmail.com。