摘要
硫辛酸(lipoic acid, LA)是一种天然存在的二硫醇化合物,是一种高效的抗氧化物质,在畜牧业中备受关注并广泛应用。硫辛酸具有独特的理化性质,可溶于水和脂肪溶剂,在体内扮演着辅酶的角色,参与线粒体能量代谢。近年研究发现,硫辛酸通过多种途径发挥抗氧化功能,包括直接清除自由基、再生其他抗氧化剂和修复氧化损伤等,具有提高畜禽抗炎、抗应激和机体免疫力的潜力。文章综述了硫辛酸的理化性质和抗氧化原理,以期促进畜禽养殖业的健康发展。
Lipoic acid is a naturally occurring dithiol compound and a highly efficient antioxidant,attracting significant attention and wide application in animal husbandry.It possesses unique physicochemical proper-ties,being soluble in both water and fat solvents,and plays a role as a coenzyme in mitochondrial energy metabolism.Recent studies have found that lipoic acid exerts its antioxidant function through multiple path-ways,including directly scavenging free radicals,regenerating other antioxidants,and repairing oxidative damage,thereby demonstrating potential in enhancing anti-inflammatory,anti-stress,and immune-modulatory capabilities of livestock and poultry.The article reviewed the physicochemical properties and antioxidant principles of lipoic acid,with the aim of promoting the healthy development of the livestock and poultry breeding industry.
作者
张子骏
栗文钰
邓诗凡
柯亮亮
张建斌
章贵峰
孙超
蒲蕾
ZHANG Zijun;LI Wenyu;DENG Shifan;KE Liangliang;ZHANG Jianbin;ZHANG Guifeng;SUN Chao;PU Lei(Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry,College of Animal Science and Veterinary Medicine,Tianjin Agricultural University,Tianjin 300384,China;Tianjin Key Laboratory of Green Ecological Feed,Tianjin 301800,China;Beijing Sanyuanhefeng Animal Husbandry Co.,Ltd.,Beijing 102200,China;Tianjin Mu Kaifeng Black Pig Breeding Co.,Ltd.,Tianjin 301900,China)
出处
《饲料工业》
2025年第19期148-153,共6页
Feed Industry
基金
大学生创新创业训练项目[202410061007、202310061006]
海南省重点研发项目[ZDYF2024XDNY271]
天津市科技计划项目[23ZYCGSN00230]
天津市农业产学研“揭榜挂帅”项目[GBGG202427]
天津市生猪产业技术体系创新团队项目[IITTPRS2025006]。
关键词
硫辛酸
二氢硫辛酸
理化性质
抗氧化
信号通路
lipoic acid
dihydrolipoic acid
physicochemical properties
antioxidant
signaling pathway
作者简介
张子骏,研究方向为动物营养与饲料科学;通信作者:蒲蕾,博士,讲师。
