摘要
研究老年肺部感染性疾病的治疗措施,探讨左氧氟沙星结合氨溴索的应用效果。选取2022年10月—2024年5月某院收治的98例老年肺部感染性疾病患者为研究对象,采用电脑双盲法将其分为对照组和观察组,每组各49例。对照组采用左氧氟沙星治疗,观察组采用左氧氟沙星联合氨溴索治疗,比较两组患者的治疗效果。结果显示,观察组患者的治疗总有效率高于对照组(P<0.05);观察组患者的发热改善时间、咳嗽减少时间、咳痰减轻时间、肺部啰音消失时间均短于对照组(P<0.05);治疗后,观察组患者的各项炎症反应指标水平均低于对照组(P<0.05);两组患者的不良反应发生情况比较,无统计学差异(P>0.05)。研究发现,在老年肺部感染性疾病患者的临床治疗中,联合应用左氧氟沙星和氨溴索治疗的效果显著且安全性高,不会增加不良反应的发生风险,对患者的临床症状改善及炎症反应减轻具有促进作用,值得推广。
To study the treatment measures for senile pulmonary infectious diseases and explore the application effect of levofloxacin combined with ambroxol.A total of 98 patients with senile pulmonary infectious diseases admitted to a certain hospital from October 2022 to May 2024 were selected as the research subjects.They were divided into a control group and an observation group by the computer double-blind method,with 49 cases in each group.The control group was treated with levofloxacin,and the observation group was treated with levofloxacin combined with ambroxol,and the treatment effects of the two groups of patients were compared.The results showed that the total treatment effective rate of the patients in the observation group was higher than that in the control group(P<0.05);the time for fever improvement,the time for cough reduction,the time for expectoration alleviation,and the time for the disappearance of pulmonary rales in the observation group were all shorter than those in the control group(P<0.05);after treatment,the levels of various inflammatory reaction indexes of the patients in the observation group were all lower than those in the control group(P<0.05);there was no statistically significant difference in the occurrence of adverse reactions between the two groups of patients(P>0.05).The study found that in the clinical treatment of patients with senile pulmonary infectious diseases,the combined application of levofloxacin and ambroxol has a significant effect and high safety,will not increase the risk of adverse reactions,and can promote the improvement of the clinical symptoms and the alleviation of the inflammatory reaction of patients,which is worthy of promotion.
作者
王静
Wang Jing(Department of Pharmacy,The First Rongjun Youfu Hospital of Shandong Province,Jinan,Shandong 250013)
出处
《科技与健康》
2025年第7期89-92,共4页
Technology and Health
关键词
左氧氟沙星
氨溴索
老年
慢性阻塞性肺疾病
肺部感染性疾病
levofloxacin
ambroxol
senile
chronic obstructive pulmonary disease
pulmonary infectious diseases
作者简介
王静(1976-),女,山东省第一荣军优抚医院药剂科主管药师,研究方向为抗感染。
