摘要
持续推进以安全、有效、经济、适当为基本原则的合理用药工作,是完善临床药品使用管理、优化医疗卫生资源配置的重要手段。药物经济学旨在将量化药品价值思维引入医疗卫生决策,系统、科学地比较分析不同医药技术所产生的经济成本和健康产出,进而形成所需的优选方案,旨在提高医药资源配置的整体效率,实现健康结果改善最大化。该文聚焦药品合理使用问题,阐述以药物经济学基础理论和研究方法为指导原则的药物经济学评价、真实世界治疗现状研究、用药模式与疾病负担因果分析,如何助力药品遴选、促进药品规范使用、完善药品上市后临床用药模式。同时,针对当前药物经济学研究面临的数据质量有待提升、研究设计不完善等问题,该文提出了针对性的建议,旨在助力药物经济学证据向更高质量的方向发展,为合理用药实践提供更加坚实的科学依据。
Continuously promoting the rational use of medicines based on the principles of safety,efficacy,economics,and appropriateness is an important approach to improve clinical management of medicines and optimize the allocation of health resources.Pharmacoeconomics aims to integrate the concept of quantifying the value of medicines into healthcare decisions,thus systematically and scientifically comparing and analyzing the economic costs and health returns of pharmaceutical technologies.It facilitates the formulation of the optimal strategy for decision-making and improvement of the overall efficiency of healthcare resource allocation.Focusing on the issue of rational use of drugs,this review explained how pharmacoeconomic evaluation,real-world treatment status research,medication use patterns and disease burden causal analysis based on the guiding principles of basic theories and research methods of pharmacoeconomics assist drug selection,promote standardized use of drugs,and improve the clinical use model of drugs after they are launched on the market.Targeting on current pharmacoeconomics research issues like insufficient data quality and imperfect study design,this review put forward targeted suggestions and solid scientific basis to help the pharmacoeconomics evidence develop in a higher quality direction and provide guidance for the practice of rational drug use.
作者
吴晶
甘磊
白雪霏
WU Jing;GAN Lei;BAI Xuefei(School of Pharmaceutical Science and Technology,Faculty of Medicine,Tianjin University,Tianjin 300072,China;Center for Social Science Survey and Data,Tianjin University,Tianjin 300072,China)
出处
《中国医院药学杂志》
北大核心
2025年第5期485-488,共4页
Chinese Journal of Hospital Pharmacy
关键词
合理用药
药物经济学
真实世界研究
因果分析
rational use of medicines
pharmacoeconomics
real-world study
causal analysis
作者简介
吴晶,女,博士,博士生导师,天津大学医学部药物科学与技术学院党委书记,教授。主要研究方向:卫生经济学与药物经济学。近5年发表英文论文(SSCI&SCI)40余篇,中文论文30余篇,主持国家自然科学基金3项,天津市自然科学基金2项,主编和副主编《药物经济学》教材4部、合著《基本药物制度:理论与实践》。《中国药物经济学评价指南》(2020)、《中国药物经济学评价指南导读》(2022)主要执笔者。主要社会兼职包括中国药学会药物经济学专业委员会主任委员、中国研究型医院学会药物经济学专业委员会副主任委员、天津市医疗保险研究会副会长、天津市药学会药物经济学专业委员会主任委员等。研究方向:卫生经济学与卫生政策评估。
