摘要
目的评价^(125)I放射性粒子植入保肛治疗不能耐受直肠癌根治术的低位直肠癌的安全性和可行性。方法回顾分析放射性粒子植入保肛治疗的8例经病理证实的不能或不愿接受直肠癌根治术的低位直肠癌患者的临床资料。结果8例低位直肠癌患者在超声引导下顺利安全地完成^(125)I放射性粒子植入手术,术前表现的黏液脓血便、会阴部疼痛、肛门下坠感、排便不净感等临床症状均显著改善,术后患者CEA水平均显著下降。4例复查肠镜、CT见肿瘤消失,所有患者均成功保留肛门功能。术后平均生存时间为32.4个月。结论放射性粒子植入保肛治疗低位直肠癌可有效提高患者的生活质量。
Objective To assess the effectiveness and characteristics of intratumoral radioactive seed im-plantation in low rectal cancer with anal sphincter preservation.Methods Clinical data of 8 patients(not willing or can not to undergo radical resection of rectal carcinoma)with low rectal cancer receiving radioactive seed implan-tation with anal sphincter preservation were retrospectively analyzed.Results All the 8 patients successfully com-pleted intratumoral radioactive seed implantation.Preoperative clinical symptoms of discomfort were significantly improved,and CEA levels decreased significantly.Colonoscopy and CT examination showed that tumor disap-peared in 4 cases,anal function was successfully preserved in all patients.The mean survival time was 32.4 months.Conclusions Intratumoral radioactive seed implantation in low rectal cancer with anal sphincter preser-vation can effectively improve the quality of life of patients.
作者
陶有茂
吕金强
盖保东
Tao Youmao;Lyu Jinqiang;Gai Baodong(Department of Gastrointestinal Colorectal and Anal Surgery,China-Japan Union Hospital of Jilin University,Chang-Chun 130033,China)
出处
《中华内分泌外科杂志》
CAS
2024年第1期94-98,共5页
Chinese Journal of Endocrine Surgery
关键词
低位直肠癌
放射性粒子
保肛手术
Low rectal cancer
Radioactive seeds
Anal preservation surgery
作者简介
通信作者:盖保东,Email:Gaibd@jlu.edu.cn。
