摘要
脂肪乳是临床上常用于重症患者肠外营养支持治疗的药物。随着医药事业的发展,脂肪乳已形成了多种不同配方的制剂,其中不同类型的脂肪乳有各自代谢和体内供能的特征,应用适应症也有所不同。除提供营养物质的供应外,脂肪乳在免疫调节、抗炎、抗休克、中毒支持治疗、心肺复苏等方面的作用不断被研究。本文对现有的循证医学证据进行梳理,阐述脂肪乳在中毒危重症患者救治过程中发挥非营养功能的机制及治疗作用,对其在救治中毒危重患者中的价值进行探讨,并为今后脂肪乳非营养功能的应用提供部分参考。
Fat emulsion is a drug commonly used clinically for parenteral nutrition support in critically ill patients.With the development of the pharmaceutical industry,fat emulsion has formed a variety of different formulations,among which different types of fat emulsion have their own metabolic and body energy supply characteristics,and the application indications are also different.In addition to providing the supply of nutrients,the role of fat emulsion in anti-toxicity,immune regulation,anti-inflammatory,anti-shock,cardiopulmonary resuscitation and other aspects has gradually been discovered.This article reviews the existing evidence-based medical evidence and expounds the mechanism and therapeutic role of fat emulsion in the treatment of critically ill patients with poisoning.Its value in the treatment of critically ill patients with poisoning was discussed,and some references were provided for the application of non-nutritional functions of fat emulsion in the future.
作者
董建光
林国东
邱泽武
Dong Jianguang;Lin Guodong;Qiu Zewu(Department of Critical Care Medicine,Tianjin Central Obstetrics and Gynecology Hospital,Tianjin 300100,China;Department of Intensive Medicine,General Hospital of the Southern Theater Command of the Chinese People's Liberation Army,Guangzhou 510010,China;Department of Chemical Injury Treatment,Fifth Medical Center,Chinese People's Liberation Army General Hospital,Beijing 100071,China)
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2024年第1期73-77,共5页
Chinese Journal of Industrial Hygiene and Occupational Diseases
基金
天津市医学重点学科(专科)建设项目(TJYXZDXK-043A)。
关键词
脂肪乳
中毒
危重症
营养
休克
Fat emulsion
Poisoning
Critical illness
Nourishment
Shock
作者简介
通信作者:林国东,E-mail:619323963@qq.com.com。
