摘要
通过溶胶-凝胶法制备出3种不同粒径的SiO_(2)微球,利用扫描电镜分析了微球的粒径分布情况,SiO_(2)微球粒径分别在140nm、208nm、336nm左右,在一定范围内,硅球的粒径随正硅酸四乙酯(TEOS)/氨水的添加量增加而增大。选取粒径在336nm左右的SiO_(2)微球,使用硅烷偶联剂3-(2,3-环氧丙氧基)丙基三甲氧基硅烷(GPTMS)将壳聚糖(CS)接枝在SiO_(2)微球上,得到SiO_(2)@CS复合微球。通过红外光谱分析、X射线衍射等对微球进行了表征。接枝CS后对SiO_(2)微球的结晶特性没有影响,微球仍为无定形晶体。元素分析结果表明CS的接枝量为1.03%。使用振荡法进行抗菌测试,SiO_(2)@CS复合微球对金黄色葡萄球菌(S.aureus)和大肠杆菌(E.coil)的抑菌率分别为85.52%和47.14%,表明复合微球有一定的抗菌效果。
Three SiO_(2) microspheres with different particle sizes were prepared by sol-gel method.The particle size distribution of the microspheres was analyzed by scanning electron microscopy,and the particle size of SiO_(2) microspheres was about 140nm,208nm and 336nm,respectively.Within a certain range,the particle size of the silicon microspheres increased with the addition of TEOS/ammonia.SiO_(2) microspheres with a particle size of about 336 nm were selected,and the silane coupling agent 3-(2,3-epoxypropoxy)propyltrimethoxysilane(GPTMS)was used to graft chitosan(CS)onto SiO_(2) microspheres to obtain SiO_(2)@CS composite microspheres.The microspheres are characterized by infrared spectroscopy and X-ray diffraction,etc.Grafting chitosan had no effect on the crystallization characteristics of SiO_(2) microspheres,which were still amorphous crystals.The results of elemental analysis showed that the grafting amount of chitosan was 1.03%.The antibacterial test using the oscillation method indicated that the bacteriostatic rates of the SiO_(2)@CS composite microspheres against staphylococcus aureus(S.aureus)and colibacillusis(E.coil)were 85.52% and 47.14%,respectively,indicating that the composite microspheres had a certain antibacterial effect.
作者
金玉珠
刘颖
刘泰佑
张建勋
Jin Yuzhu;Liu Ying;Liu Taiyou;Zhang Jianxun(School of Textile Science and Engineering,Jiangnan University,Wuxi 214122)
出处
《化工新型材料》
CAS
CSCD
北大核心
2023年第11期138-141,共4页
New Chemical Materials
基金
江苏省自然科学基金青年基金项目(BK20190606)
中国博士后科学基金第68批面上资助(2020M681486)。
关键词
二氧化硅
壳聚糖
微球
抗菌材料
SiO_(2)
chitosan
microspheres
antibacterial materials
作者简介
金玉珠(1999-),女,硕士,主要从事疏水、抗菌等功能材料研究,E-mail:jinyuzhuo817@foxmail.com;通讯作者:刘颖(1987-),女,副研究员,主要研究方向为新型抗菌剂制备、纺织品的抗菌、抗紫外等功能性整理及抗菌复合材料制备等,E-mail:liuying@jiangnan.edu.cn。
