摘要
目的:分析冠心病患者临床检验中血清胆红素与尿酸的诊断价值。方法:选取2022年3月—2023年3月大化瑶族自治县人民医院收治的冠心病患者48例作为研究对象,设定为观察组,同时选取体检中心健康人群48例作为对照组。比较两组受检者血清胆红素(包括直接胆红素、间接胆红素、血清总胆红素)和尿酸水平,观察组4个亚组(Gensini≤1分组,Gensini 2~19分组,Gensini 20~40分组和Gensini>40组)的血清胆红素和尿酸水平,血清胆红素联合尿酸的诊断效能。结果:观察组直接胆红素、间接胆红素和血清总胆红素水平低于对照组,尿酸水平高于对照组,差异有统计学意义(P<0.001);Gensini分值越高,观察组直接胆红素、间接胆红素和血清总胆红素水平呈逐渐下降趋势,尿酸呈上升趋势,差异有统计学意义(P<0.05);血清胆红素联合尿酸诊断的灵敏度和特异度均高于血清胆红素和尿酸单一诊断,差异有统计学意义(P<0.05)。结论:血清胆红素和尿酸水平在冠心病的诊断中具有一定参考价值,建议临床可以将二者联合检测作为冠心病临床检验指标。
Objective:To analyze the diagnostic value of serum bilirubin and uric acid in clinical tests of patients with coronary heart disease.Methods:Forty-eight cases of coronary heart disease patients admitted to Dahua Yao Autonomous County People's Hospital from March 2022 to March 2023 were selected as the study subjects and set as the observation group,while forty-eight cases of healthy people in the physical examination center were selected as the control group.Comparison of serum bilirubin(including direct bilirubin,indirect bilirubin,total serum bilirubin)and uric acid levels between the two groups of subjects,serum bilirubin and uric acid levels in four subgroups of the observation group(Gensini≤1 group,Gensini 2-19 group,Gensini 20-40 group and Gensini>40 group),diagnostic efficacy of serum bilirubin combined with uric acid.Results:The levels of direct bilirubin,indirect bilirubin and total serum bilirubin in the observation group were lower than those in the control group,and the levels of uric acid were higher than those in the control group,and the difference was statistically significant(P<0.001);The higher the Gensini score,the gradual decreasing trend of direct bilirubin,indirect bilirubin and serum total bilirubin levels and the increasing trend of uric acid in the observation group,and the difference was statistically significant(P<0.05);The sensitivity and specificity of serum bilirubin combined with uric acid diagnosis were higher than that of serum bilirubin and uric acid single diagnosis,and the difference was statistically significant(P<0.05).Conclusion:Serum bilirubin and uric acid levels have certain reference value in the diagnosis of coronary heart disease,and it is suggested that the clinic can use the combined detection of the two as a clinical test index for coronary heart disease.
作者
向柏
Xiang Bai(Dahua Yao Autonomous County People's Hospital,Hechi 530800,Guangxi Zhuang Autonomous Region,China)
出处
《中外医药研究》
2023年第18期147-149,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
血清胆红素
尿酸
冠心病
Serum bilirubin
Uric acid
Coronary heart disease
