摘要
Due to the COVID-19 pandemic,many rapid antimicrobial agents have developed intensively.Carbon dots(CDs),a new type of carbon-based nanomaterials,shows great potential against emerging infectious diseases and antimicrobial-resistant infections due to their unique optical properties,excellent biocompatibility,and easy surface modification.With the definition of the CDs structure and properties,synthesis,and characteristic technology improvement,the research on the CDs as antimicrobial agents has made significant progress.However,the lack of high repeatable and exact preparation methods,and the regular antimicrobial activity make it far from practical application.In this review,we summarize the most recent progress and challenges of CDs antimicrobial.First,an overview of the characteristics and properties is given,and the advantage of CDs applied to antimicrobial is further discussed.Then,it focuses on research progress on antimicrobial mechanisms under different conditions,the critical factors affecting their antimicrobial activity,and the practical antimicrobial applications.Finally,the main challenges and future research perspectives of antimicrobial CDs are proposed.
基金
supported by the Beijing Municipal High-Level Innovative Team Building Program(No.IDHT20180504)
the Beijing Outstanding Young Scientists Program(No.BJJWZYJH01201910005017)
the National Natural Science Foundation of China(Nos.21872001,51801006,and 21805004)
the Key Project of the National Natural Science Foundation of China(Nos.21936001 and 21801092)
the Beijing Natural Science Foundation(No.2192005)
the Beijing Municipal Science and Natural Science Fund Project(No.KM201910005016).
作者简介
Correspondence:Zaicheng Sun,Department of Chemistry and Biology,Beijing Key Laboratory for Green Catalysis and Separation,Center of Excellence for Environmental Safety and Biological Effects,Beijing University of Technology,100 Pingleyuan,Beijing 100124,China.Email:sunzc@bjut.edu.cn;Pengfei Li is a PhD student at Beijing Key Laboratory for Green Catalysis and Separation,Department of Chemistry and Chemical Engineering,Beijing University of Technology.His current research interests focus on the fluorescence mechanism of CDs and the antimicrobial application of CDs;Zaicheng Sun received his PhD degree in Chemistry from Changchun Institute of Applied Chemistry,CAS.After that,he started to work as an AvH research fellow at Marburg University in Germany.Followed by a research associate at UW,UDel,and UNM.He took the professor position at Changchun Institute of Optics,Fine Mechanics and Physics,CAS in 2010.He is currently a professor in the Department of Chemistry and Biology,Beijing University of Technology.His research focuses on the rational design of photocatalyst with high charge separation efficiency and fluorescent carbon dots with tunable emission and their applications.
