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糖尿病下肢动脉硬化闭塞症的介入术后再狭窄机制与中西医防治 被引量:11

Mechanisms of restenosis after interventional surgery in diabetic lower extremity arteriosclerosis obliterans and the prevention and treatment strategy
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摘要 下肢动脉硬化闭塞症是糖尿病常见的慢性并发症之一,其以动脉增厚、变硬、伴有粥样斑块和钙化为病理特征,临床表现为患肢发冷、疼痛、麻木、间歇性跛行,患者趾或足容易发生溃疡或坏死,严重时可致截肢,严重影响糖尿病患者的生存质量和加重患者与社会的经济负担。介入治疗风险低,重复性好,临床效果好,已成为治疗下肢动脉硬化闭塞症的主要手段,但其远期通畅率仍不理想。对介入术后的再次狭窄的预定成为目前有待解决的难题,中西医药物结合为介入后再次狭窄的预防提供了有效的方法。 Lower extremity arteriosclerosis obliterans are one of the common chronic complications of diabetes.The arterialthickening,hardening,associated with atherosclerotic plaque and calcification are pathological features.The clinical manifestations arechills,pain,numbness and intermittent claudication in injured limb,toes or feet of patients prone to ulcers or necrosis,severe amputationcan be caused,seriously impact on the quality of life of patients with diabetes and increase the economic burden of patients and society.Intervention treatment showed low risk,good reproducibility and good clinical effect,has become the main method for lower extremityarteriosclerosis obliterans;but the long-term patency is still not ideal.Restenosis after interventional surgery is becoming a problem to besolved at present.The combination of TCM and western medicine provides an effective method to prevent from stenosis after intervention.
出处 《中医临床研究》 2017年第14期139-142,共4页 Clinical Journal Of Chinese Medicine
关键词 糖尿病 下肢动脉硬化闭塞 介入 再狭窄 中西医防治 Diabetes mellitus Lower extremity arteriosclerosis occlusion Intervention Restenosis The prevention and treatment strategy of the integrative medicine
作者简介 莫兴骊(1984-),女,护师;刘惠娟(1989-),女,住院医师;莫兴骝(1984-),通讯作者,2013级研究生
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