摘要
目的测定咳嗽变异性哮喘(CVA)患儿呼出气一氧化氮(FeNO)的变化,探讨FeNO在儿童CVA中的诊断价值。方法 2015年1月至2016年10月抚顺矿务局总医院儿科收治CVA患儿30例,为CVA组;同期选取感染后咳嗽(PIC)患儿30例,为PIC组。分别测定两组患儿FeNO和IgE水平。结果两组FeNO、IgE水平均升高,CVA组FeNO水平为(33.23±16.29)×10^(-9) mol/L,显著高于PIC组(19.30±9.87)×10^(-9) mol/L,差异有统计学意义(P<0.01);IgE水平两组比较差异无统计学意义(P>0.05)。结论在儿童慢性咳嗽的诊断中,FeNO可作为辅助诊断CVA的一种检测方法。
Objective To determine the changes of exhaled nitric oxide（FeNO）in children with cough variant asthma（CVA）,and to explore the diagnostic value of FeNO in children＇s CVA.Methods Thirty cases of children with CVA admitted to Pediatric Department of Fushun Mining Administration General Hospital from January 2015 to October 2016 were set as CVA group;30 cases of children with cough（PIC）after infection were selected during the same period and they were set as PIC group.The levels of FeNO and IgE were measured separately in two groups.Results The levels of FeNO and IgE were increased in both groups,The levels in CVA group were（33.23±16.29）×10-9 mol/L,significantly higher than those of the PIC group[（19.30±9.87）×10-9 mol/L],the difference being statistically significant（P〈0.01）.There was no significant difference in IgE levels between the two groups（P〈0.05）.Conclusion In the diagnosis of chronic cough in children,FeNO can be used as a diagnostic method for the diagnosis of CVA.
作者
苏艳琦
王丹
闫昕婕
范雪
SU Yanqi;WANG Dan;YAN Xinjie;FAN Xue(Department of Padiatrics,Fushun Mining Administration General Hospital,Fushun 113008,China)
出处
《中国中西医结合儿科学》
2018年第3期200-202,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
作者简介
通讯作者：苏艳琦（19G8），女，医学硕士，主任医师。研究方向：小儿呼吸系统疾病的诊治及小儿急救，E-mail：fsyq@sina．com.
